Functional interaction of beta-catenin with the transcription factor LEF-1 (Q28286884)

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Language	Label	Description	Also known as
English	Functional interaction of beta-catenin with the transcription factor LEF-1	scientific article

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scholarly article

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Functional interaction of beta-catenin with the transcription factor LEF-1 (English)

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beta-catenin-TCF complex

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Gene Ontology release 2020-05-02

Gene Ontology ID

author name string

J Behrens

1

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J P von Kries

2

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M Kühl

3

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L Bruhn

4

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D Wedlich

5

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R Grosschedl

6

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W Birchmeier

7

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language of work or name

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publication date

15 August 1996

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382

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6592

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638-42

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E-cadherin and APC compete for the interaction with beta-catenin and the cytoskeleton

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The roles of catenins in the cadherin-mediated cell adhesion: functional analysis of E-cadherin-alpha catenin fusion molecules

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A homolog of the armadillo protein in Drosophila (plakoglobin) associated with E-cadherin

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A repeating amino acid motif shared by proteins with diverse cellular roles

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dishevelled and armadillo act in the wingless signalling pathway in Drosophila

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Embryonic axis induction by the armadillo repeat domain of beta-catenin: evidence for intracellular signaling

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LEF-1, a gene encoding a lymphoid-specific protein with an HMG domain, regulates T-cell receptor alpha enhancer function [corrected]

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A thymus-specific member of the HMG protein family regulates the human T cell receptor C alpha enhancer

1 reference

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Assembly and function of a TCR alpha enhancer complex is dependent on LEF-1-induced DNA bending and multiple protein-protein interactions

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A novel genetic system to detect protein-protein interactions

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The nuclear localization signal of lymphoid enhancer factor-1 is recognized by two differentially expressed Srp1-nuclear localization sequence receptor proteins

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Plakoglobin: a protein common to different kinds of intercellular adhering junctions

1 reference

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The HMG domain of lymphoid enhancer factor 1 bends DNA and facilitates assembly of functional nucleoprotein structures

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Structural basis for DNA bending by the architectural transcription factor LEF-1

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Fos-Jun heterodimers and Jun homodimers bend DNA in opposite orientations: implications for transcription factor cooperativity

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Lef1 expression is activated by BMP-4 and regulates inductive tissue interactions in tooth and hair development

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Ectopic expression of the proto-oncogene int-1 in Xenopus embryos leads to duplication of the embryonic axis.

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Overexpression of cadherins and underexpression of beta-catenin inhibit dorsal mesoderm induction in early Xenopus embryos

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A new member of the frizzled family from Drosophila functions as a Wingless receptor

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Regulation of intracellular beta-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein

1 reference

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LEF-1 contains an activation domain that stimulates transcription only in a specific context of factor-binding sites.

1 reference

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based on heuristic

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The hLEF/TCF-1 alpha HMG protein contains a context-dependent transcriptional activation domain that induces the TCR alpha enhancer in T cells

1 reference

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Bending of DNA by gene-regulatory proteins: construction and use of a DNA bending vector

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Functional messenger RNAs are produced by SP6in vitrotranscription of cloned cDNAs

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Dominant negative expression of a cytoplasmically deleted mutant of XB/U-cadherin disturbs mesoderm migration during gastrulation in Xenopus laevis

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