Hsp90 phosphorylation, Wee1 and the cell cycle (Q28284142)

12 December 2020

Global proteomic profiling of phosphopeptides using electron transfer dissociation tandem mass spectrometry.

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12 December 2020

Phosphorylation analysis of 90 kDa heat shock protein within the cytosolic arylhydrocarbon receptor complex

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12 December 2020

Human Wee1 kinase inhibits cell division by phosphorylating p34cdc2 exclusively on Tyr15

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12 December 2020

Hsp90 charged-linker truncation reverses the functional consequences of weakened hydrophobic contacts in the N domain

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12 December 2020

Incapacitating the evolutionary capacitor: Hsp90 modulation of disease

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12 December 2020

Signaling networks assembled by oncogenic EGFR and c-Met

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12 December 2020

Protein kinase A-dependent translocation of Hsp90 alpha impairs endothelial nitric-oxide synthase activity in high glucose and diabetes

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12 December 2020

Two human 90-kDa heat shock proteins are phosphorylated in vivo at conserved serines that are phosphorylated in vitro by casein kinase II.

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12 December 2020

Heat shock increases turnover of 90 kDa heat shock protein phosphate groups in HeLa cells

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12 December 2020

Post-translational modification of heat-shock protein 90: impact on chaperone function

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12 December 2020

A proteomic screen identified stress-induced chaperone proteins as targets of Akt phosphorylation in mesangial cells

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12 December 2020

Properties of Saccharomyces cerevisiae wee1 and its differential regulation of p34CDC28 in response to G1 and G2 cyclins

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12 December 2020

ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage

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12 December 2020

Conformational dynamics of the molecular chaperone Hsp90 in complexes with a co-chaperone and anticancer drugs

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12 December 2020

Investigating the protein-protein interactions of the yeast Hsp90 chaperone system by two-hybrid analysis: potential uses and limitations of this approach

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12 December 2020

Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer

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12 December 2020

Conservation of mechanisms controlling entry into mitosis: budding yeast wee1 delays entry into mitosis and is required for cell size control

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12 December 2020

Identification and structural characterization of the ATP/ADP-binding site in the Hsp90 molecular chaperone

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12 December 2020

Hydroxamic acid analogue histone deacetylase inhibitors attenuate estrogen receptor-alpha levels and transcriptional activity: a result of hyperacetylation and inhibition of chaperone function of heat shock protein 90.

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12 December 2020

Hsp90 phosphorylation is linked to its chaperoning function. Assembly of the reovirus cell attachment protein

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12 December 2020

The Hsp90 molecular chaperone: an open and shut case for treatment

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12 December 2020

Hsp90 as a capacitor for morphological evolution

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12 December 2020

Update on Hsp90 inhibitors in clinical trial.

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12 December 2020

S-nitrosylation of Hsp90 promotes the inhibition of its ATPase and endothelial nitric oxide synthase regulatory activities

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12 December 2020

ATP binding and hydrolysis are essential to the function of the Hsp90 molecular chaperone in vivo

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12 December 2020

The large conformational changes of Hsp90 are only weakly coupled to ATP hydrolysis

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12 December 2020

Domain mapping studies reveal that the M domain of hsp90 serves as a molecular scaffold to regulate Akt-dependent phosphorylation of endothelial nitric oxide synthase and NO release

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12 December 2020

The 90-kDa heat shock protein, HSP90, binds and protects casein kinase II from self-aggregation and enhances its kinase activity.

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12 December 2020

Control of Swe1p degradation by the morphogenesis checkpoint

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12 December 2020

High Affinity Binding of Hsp90 Is Triggered by Multiple Discrete Segments of Its Kinase Clients

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12 December 2020

A multidimensional chromatography technology for in-depth phosphoproteome analysis

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12 December 2020

Modulating molecular chaperone Hsp90 functions through reversible acetylation.

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12 December 2020

The human double-stranded DNA-activated protein kinase phosphorylates the 90-kDa heat-shock protein, hsp90 alpha at two NH2-terminal threonine residues

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12 December 2020

Heat shock protein 90: the cancer chaperone

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12 December 2020

Inhibition of apoptosome formation by suppression of Hsp90beta phosphorylation in tyrosine kinase-induced leukemias

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12 December 2020

Hsp90 chaperone complexes are required for the activity and stability of yeast protein kinases Mik1, Wee1 and Swe1.

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12 December 2020

Species-dependent ensembles of conserved conformational states define the Hsp90 chaperone ATPase cycle

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12 December 2020

Hsp90 and co-chaperones twist the functions of diverse client proteins

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12 December 2020

Spatially and kinetically resolved changes in the conformational dynamics of the Hsp90 chaperone machine

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12 December 2020

Swe1Wee1-dependent tyrosine phosphorylation of Hsp90 regulates distinct facets of chaperone function

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12 December 2020

Phosphorylation-independent inhibition of Cdc28p by the tyrosine kinase Swe1p in the morphogenesis checkpoint

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12 December 2020

Crystal structure of an Hsp90-nucleotide-p23/Sba1 closed chaperone complex

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12 December 2020

The charged linker region is an important regulator of Hsp90 function

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12 December 2020

Phosphorylation and hsp90 binding mediate heat shock stabilization of p53

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12 December 2020

The morphogenesis checkpoint: how yeast cells watch their figures

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12 December 2020

Phosphorylation and oligomerization states of native pig brain HSP90 studied by mass spectrometry

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12 December 2020

Functional proteomics identifies targets of phosphorylation by B-Raf signaling in melanoma

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12 December 2020

The Hsp90 chaperone machinery

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12 December 2020

Global, in vivo, and site-specific phosphorylation dynamics in signaling networks

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12 December 2020

Tyrosine phosphorylation of HSP90 within the P2X7 receptor complex negatively regulates P2X7 receptors

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12 December 2020

A role for Hsp90 in cell cycle control: Wee1 tyrosine kinase activity requires interaction with Hsp90.

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12 December 2020

The 90-kilodalton peptide of the heme-regulated eIF-2 alpha kinase has sequence similarity with the 90-kilodalton heat shock protein

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12 December 2020

The identification of Wos2, a p23 homologue that interacts with Wee1 and Cdc2 in the mitotic control of fission yeasts

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12 December 2020

A systematic MS-based approach for identifying in vitro substrates of PKA and PKG in rat uteri

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12 December 2020

Dissection of the ATP-induced conformational cycle of the molecular chaperone Hsp90.

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12 December 2020

A quantitative atlas of mitotic phosphorylation

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12 December 2020

Navigating the chaperone network: an integrative map of physical and genetic interactions mediated by the hsp90 chaperone

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12 December 2020

The phosphatase Ppt1 is a dedicated regulator of the molecular chaperone Hsp90

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12 December 2020

Src-mediated phosphorylation of Hsp90 in response to vascular endothelial growth factor (VEGF) is required for VEGF receptor-2 signaling to endothelial NO synthase.

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12 December 2020

Wee1-dependent mechanisms required for coordination of cell growth and cell division

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12 December 2020

Evidence for an epigenetic mechanism by which Hsp90 acts as a capacitor for morphological evolution.

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12 December 2020

Systematic identification of pathways that couple cell growth and division in yeast

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12 December 2020

Possible role for serine/threonine phosphorylation in the regulation of the heteroprotein complex between the hsp90 stress protein and the pp60v-src tyrosine kinase

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12 December 2020