A multimodal RAGE-specific inhibitor reduces amyloid β-mediated brain disorder in a mouse model of Alzheimer disease (Q28261647)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22406537%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

title

A multimodal RAGE-specific inhibitor reduces amyloid β-mediated brain disorder in a mouse model of Alzheimer disease (English)

1 reference

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25 January 2020

0 references

1 reference

advanced glycosylation end-product specific receptor

1 reference

Amyloid beta precursor protein

1 reference

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

1 reference

Advanced glycosylation end product-specific receptor

1 reference

1 reference

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25 January 2020

1 reference

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25 January 2020

1 reference

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25 January 2020

1 reference

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25 January 2020

Rashid Deane

1 reference

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25 January 2020

Itender Singh

1 reference

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25 January 2020

Abhay P Sagare

1 reference

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25 January 2020

Robert D Bell

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22406537%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Nathan T Ross

1 reference

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25 January 2020

Barbra LaRue

1 reference

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25 January 2020

Sheldon Perry

1 reference

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25 January 2020

Nicole Paquette

1 reference

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25 January 2020

Richard J Deane

1 reference

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25 January 2020

Meenakshisundaram Thiyagarajan

1 reference

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25 January 2020

Troy Zarcone

1 reference

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25 January 2020

Berislav V Zlokovic

1 reference

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25 January 2020

language of work or name

English

0 references

publication date

12 March 2012

1 reference

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Journal of Clinical Investigation

25 January 2020

published in

1 reference

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25 January 2020

volume

122

1 reference

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25 January 2020

issue

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25 January 2020

page(s)

1377-1392

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describes a project that uses

25 January 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3314449/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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29 September 2017

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29 September 2017

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29 September 2017

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2 June 2018

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2 June 2018

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2 June 2018

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2 June 2018

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2 June 2018

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AGEs/RAGE complex upregulates BACE1 via NF-κB pathway activation

27 November 2018

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27 November 2018

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27 November 2018

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27 November 2018

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27 November 2018

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27 November 2018

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27 November 2018

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27 November 2018

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Studies of Abeta pharmacodynamics in the brain, cerebrospinal fluid, and plasma in young (plaque-free) Tg2576 mice using the gamma-secretase inhibitor N2-[(2S)-2-(3,5-difluorophenyl)-2-hydroxyethanoyl]-N1-[(7S)-5-methyl-6-oxo-6,7-dihydro-5H-dibenzo[

27 November 2018

1 reference

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RAGE mediates amyloid-beta peptide transport across the blood-brain barrier and accumulation in brain

27 November 2018

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27 November 2018

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27 November 2018

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Involvement of microglial receptor for advanced glycation endproducts (RAGE) in Alzheimer's disease: identification of a cellular activation mechanism.

27 November 2018

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27 November 2018

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27 November 2018

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Non-enzymatically glycated tau in Alzheimer's disease induces neuronal oxidant stress resulting in cytokine gene expression and release of amyloid beta-peptide.

27 November 2018

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27 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/22406537

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Evidence for a lactate transport system in the sarcolemmal membrane of the perfused rabbit heart: kinetics of unidirectional influx, carrier specificity and effects of glucagon

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22406537

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1172/JCI58642

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22406537%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22406537%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

PubMed publication ID

22406537

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22406537%20AND%20SRC:MED&resulttype=core&format=json