RAGE mediates amyloid-beta peptide transport across the blood-brain barrier and accumulation in brain (Q44479225)

3 December 2017

title

RAGE mediates amyloid-beta peptide transport across the blood-brain barrier and accumulation in brain (English)

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advanced glycosylation end-product specific receptor

3 December 2017

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positive regulation of endothelin production

GOA release 2020-03-11

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Advanced glycosylation end product-specific receptor

GOA release 2020-03-11

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GOA release 2020-03-11

Don L Armstrong

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Peter Nawroth

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3 December 2017

Ann Marie Schmidt

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3 December 2017

Rashid Deane

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3 December 2017

Shi Du Yan

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3 December 2017

Ram Kumar Submamaryan

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3 December 2017

Barbara LaRue

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3 December 2017

Suzana Jovanovic

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3 December 2017

Elizabeth Hogg

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3 December 2017

Deborah Welch

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3 December 2017

Lawrence Manness

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3 December 2017

Chang Lin

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3 December 2017

Jin Yu

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3 December 2017

Hong Zhu

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3 December 2017

Jorge Ghiso

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3 December 2017

Blas Frangione

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3 December 2017

Alan Stern

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3 December 2017

Bernd Arnold

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3 December 2017

Birgit Liliensiek

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3 December 2017

Florence Hofman

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3 December 2017

Mark Kindy

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3 December 2017

David Stern

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3 December 2017

Berislav Zlokovic

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3 December 2017

language of work or name

English

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publication date

1 July 2003

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3 December 2017

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3 December 2017

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3 December 2017

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3 December 2017

page(s)

907-913

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Clearing the brain's amyloid cobwebs

3 December 2017

cites work

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7 January 2021

RAGE and amyloid-beta peptide neurotoxicity in Alzheimer's disease

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7 January 2021

Atlantic forest extinctions

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7 January 2021

Clearance of Alzheimer's amyloid-ss(1-40) peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier

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7 January 2021

Clearance of amyloid beta-peptide from brain: transport or metabolism?

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7 January 2021

Brain clearance of Alzheimer's amyloid-beta40 in the squirrel monkey: a SPECT study in a primate model of cerebral amyloid angiopathy

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7 January 2021

Brain to plasma amyloid-beta efflux: a measure of brain amyloid burden in a mouse model of Alzheimer's disease

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7 January 2021

Plaque-associated disruption of CSF and plasma amyloid-beta (Abeta) equilibrium in a mouse model of Alzheimer's disease

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7 January 2021

Circulating amyloid-beta peptide crosses the blood-brain barrier in aged monkeys and contributes to Alzheimer's disease lesions

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7 January 2021

Blood-brain barrier transport of circulating Alzheimer's amyloid beta

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7 January 2021

Passage of human amyloid beta-protein 1-40 across the murine blood-brain barrier

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7 January 2021

Blood-brain barrier uptake of the 40 and 42 amino acid sequences of circulating Alzheimer's amyloid beta in guinea pigs

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7 January 2021

Glycoprotein 330/megalin: probable role in receptor-mediated transport of apolipoprotein J alone and in a complex with Alzheimer disease amyloid beta at the blood-brain and blood-cerebrospinal fluid barriers

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7 January 2021

Isoform‐Specific Effects of Apolipoproteins E2, E3, and E4 on Cerebral Capillary Sequestration and Blood‐Brain Barrier Transport of Circulating Alzheimer's Amyloid β

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7 January 2021

Receptor-mediated transport of human amyloid beta-protein 1-40 and 1-42 at the blood-brain barrier

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7 January 2021

Targeting alzheimer amyloid plaques in vivo

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7 January 2021

Substitution at codon 22 reduces clearance of Alzheimer's amyloid-beta peptide from the cerebrospinal fluid and prevents its transport from the central nervous system into blood

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7 January 2021

Immunization with a nontoxic/nonfibrillar amyloid-beta homologous peptide reduces Alzheimer's disease-associated pathology in transgenic mice

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7 January 2021

Novel therapeutic approach for the treatment of Alzheimer's disease by peripheral administration of agents with an affinity to beta-amyloid.

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7 January 2021

Serum insulin-like growth factor I regulates brain amyloid-beta levels

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7 January 2021

RAGE mediates a novel proinflammatory axis: a central cell surface receptor for S100/calgranulin polypeptides

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7 January 2021

Receptor-dependent cell stress and amyloid accumulation in systemic amyloidosis

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7 January 2021

Human blood-brain barrier receptors for Alzheimer's amyloid-beta 1- 40. Asymmetrical binding, endocytosis, and transcytosis at the apical side of brain microvascular endothelial cell monolayer

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7 January 2021

Age-dependent changes in brain, CSF, and plasma amyloid (beta) protein in the Tg2576 transgenic mouse model of Alzheimer's disease.

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7 January 2021

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

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7 January 2021

Plaque-independent disruption of neural circuits in Alzheimer's disease mouse models

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7 January 2021

Central role of RAGE-dependent neointimal expansion in arterial restenosis

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7 January 2021

TGF-beta1 promotes microglial amyloid-beta clearance and reduces plaque burden in transgenic mice.

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7 January 2021

Mechanisms underlying the vascular activity of beta-amyloid protein fragment (beta A(4)25-35) at the level of skin microvasculature

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7 January 2021

SOD1 rescues cerebral endothelial dysfunction in mice overexpressing amyloid precursor protein

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7 January 2021

Intraneuronal Alzheimer abeta42 accumulates in multivesicular bodies and is associated with synaptic pathology

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7 January 2021

Soluble beta-amyloid peptides mediate vasoactivity via activation of a pro-inflammatory pathway.

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7 January 2021

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7 January 2021

Effects of TNF-α on the Production of Vasoactive Substances by Cerebral Endothelial and Smooth Muscle Cells in Culture

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7 January 2021

Effect of recombinant human tumor necrosis factor-alpha on cerebral oxygen uptake, cerebrospinal fluid lactate, and cerebral blood flow in the rabbit: role of nitric oxide

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7 January 2021

Endothelin 1 transcription is controlled by nuclear factor-kappaB in AGE-stimulated cultured endothelial cells

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7 January 2021

Advanced glycation end products (AGEs) on the surface of diabetic erythrocytes bind to the vessel wall via a specific receptor inducing oxidant stress in the vasculature: a link between surface-associated AGEs and diabetic complications

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7 January 2021

Receptor-mediated endothelial cell dysfunction in diabetic vasculopathy. Soluble receptor for advanced glycation end products blocks hyperpermeability in diabetic rats

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7 January 2021

Alterations in cerebral blood flow and glucose utilization in mice overexpressing the amyloid precursor protein

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7 January 2021

Quantitative measurement of local cerebral blood flow in the anesthetized mouse using intraperitoneal [14C]iodoantipyrine injection and final arterial heart blood sampling

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7 January 2021

Identifiers

DOI

10.1038/NM890

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3 December 2017

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