Loss of cadherin-binding proteins β-catenin and plakoglobin in the heart leads to gap junction remodeling and arrhythmogenesis (Q28257671)

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English	Loss of cadherin-binding proteins β-catenin and plakoglobin in the heart leads to gap junction remodeling and arrhythmogenesis	scientific article

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instance of

scholarly article

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title

Loss of cadherin-binding proteins β-catenin and plakoglobin in the heart leads to gap junction remodeling and arrhythmogenesis (English)

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main subject

cell biology

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author

Erhe Gao

series ordinal

3

object named as

Erhe Gao

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author name string

David Swope

series ordinal

1

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Lan Cheng

series ordinal

2

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Jifen Li

series ordinal

4

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Glenn L Radice

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5

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language of work or name

English

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publication date

March 2012

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published in

Molecular and Cellular Biology

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volume

32

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issue

6

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page(s)

1056-67

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cites work

Restrictive loss of plakoglobin in cardiomyocytes leads to arrhythmogenic cardiomyopathy

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20 March 2017

Alterations in adhesion junction precede gap junction remodelling during the development of heart failure in cardiomyopathic hamsters

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20 March 2017

Cortactin is required for N-cadherin regulation of Kv1.5 channel function

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20 March 2017

Cardiac tissue-restricted deletion of plakoglobin results in progressive cardiomyopathy and activation of {beta}-catenin signaling

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20 March 2017

Stabilised beta-catenin in postnatal ventricular myocardium leads to dilated cardiomyopathy and premature death

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20 March 2017

Comprehensive desmosome mutation analysis in north americans with arrhythmogenic right ventricular dysplasia/cardiomyopathy

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20 March 2017

Plakoglobin is required for effective intermediate filament anchorage to desmosomes

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PubMed Central

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20 March 2017

A novel dominant mutation in plakoglobin causes arrhythmogenic right ventricular cardiomyopathy

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PubMed Central

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20 March 2017

alpha-E-catenin inactivation disrupts the cardiomyocyte adherens junction, resulting in cardiomyopathy and susceptibility to wall rupture

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PubMed Central

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20 March 2017

Suppression of canonical Wnt/beta-catenin signaling by nuclear plakoglobin recapitulates phenotype of arrhythmogenic right ventricular cardiomyopathy

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PubMed Central

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20 March 2017

Ultrastructural evidence of intercalated disc remodelling in arrhythmogenic right ventricular cardiomyopathy: an electron microscopy investigation on endomyocardial biopsies

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PubMed Central

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20 March 2017

The beta-catenin/T-cell factor/lymphocyte enhancer factor signaling pathway is required for normal and stress-induced cardiac hypertrophy

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PubMed Central

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20 March 2017

The area composita of adhering junctions connecting heart muscle cells of vertebrates. I. Molecular definition in intercalated disks of cardiomyocytes by immunoelectron microscopy of desmosomal proteins

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PubMed Central

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20 March 2017

Induced deletion of the N-cadherin gene in the heart leads to dissolution of the intercalated disc structure

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PubMed Central

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20 March 2017

Conduction slowing and sudden arrhythmic death in mice with cardiac-restricted inactivation of connexin43

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PubMed Central

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20 March 2017

Embryonic heart and skin defects in mice lacking plakoglobin

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PubMed Central

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20 March 2017

Targeted mutation of plakoglobin in mice reveals essential functions of desmosomes in the embryonic heart

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PubMed Central

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20 March 2017

Structural basis of cell-cell adhesion by cadherins

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PubMed Central

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20 March 2017

A unique and specific interaction between alphaT-catenin and plakophilin-2 in the area composita, the mixed-type junctional structure of cardiac intercalated discs

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PubMed Central

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20 March 2017

Desmosomal localization of beta-catenin in the skin of plakoglobin null-mutant mice

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PubMed Central

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20 March 2017

Phosphatase-Resistant Gap Junctions Inhibit Pathological Remodeling and Prevent Arrhythmias

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PubMed Central

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29 September 2017

The cardiac desmosome and arrhythmogenic cardiomyopathies: from gene to disease.

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PubMed Central

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29 September 2017

Arrhythmogenic cardiomyopathy: etiology, diagnosis, and treatment

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PubMed Central

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29 September 2017

Limited forward trafficking of connexin 43 reduces cell-cell coupling in stressed human and mouse myocardium

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PubMed Central

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29 September 2017

N-cadherin haploinsufficiency affects cardiac gap junctions and arrhythmic susceptibility.

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PubMed Central

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29 September 2017

Desmosomes: new perspectives on a classic

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PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295003

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29 September 2017

Microtubule plus-end-tracking proteins target gap junctions directly from the cell interior to adherens junctions

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PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295003

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29 September 2017

Dysregulation of cell adhesion proteins and cardiac arrhythmogenesis

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PubMed Central

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29 September 2017

Adhesion molecules: why they are important to the electrophysiologist

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PubMed Central

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29 September 2017

Identification of a deletion in plakoglobin in arrhythmogenic right ventricular cardiomyopathy with palmoplantar keratoderma and woolly hair (Naxos disease).

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PubMed Central

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29 September 2017

Wnt-1 regulation of connexin43 in cardiac myocytes

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PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295003

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29 September 2017

Selective monoclonal antibody recognition and cellular localization of an unphosphorylated form of connexin43.

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PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295003

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29 September 2017

Gene recombination in postmitotic cells. Targeted expression of Cre recombinase provokes cardiac-restricted, site-specific rearrangement in adult ventricular muscle in vivo.

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PubMed Central

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29 September 2017

Cardiac abnormalities in familial palmoplantar keratosis

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PubMed Central

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29 September 2017

A uniform enzymatic method for dissociation of myocytes from hearts and stomachs of vertebrates.

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PubMed Central

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2 June 2018

Load-Reducing Therapy Prevents Development of Arrhythmogenic Right Ventricular Cardiomyopathy in Plakoglobin-Deficient Mice

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PubMed Central

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27 November 2018

A new diagnostic test for arrhythmogenic right ventricular cardiomyopathy

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PubMed Central

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27 November 2018

Age- and Training-Dependent Development of Arrhythmogenic Right Ventricular Cardiomyopathy in Heterozygous Plakoglobin-Deficient Mice

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PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295003

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27 November 2018

The area composita of adhering junctions connecting heart muscle cells of vertebrates. II. Colocalizations of desmosomal and fascia adhaerens molecules in the intercalated disk

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PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295003

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27 November 2018

Cardiac-Specific Loss of N-Cadherin Leads to Alteration in Connexins With Conduction Slowing and Arrhythmogenesis

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PubMed Central

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27 November 2018

Temporally regulated and tissue-specific gene manipulations in the adult and embryonic heart using a tamoxifen-inducible Cre protein

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PubMed Central

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27 November 2018

Effects of diminished expression of connexin43 on gap junction number and size in ventricular myocardium

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PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295003

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27 November 2018

Use of telemetry to record electrocardiogram and heart rate in freely moving mice.

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PubMed Central

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27 November 2018

Mechanisms underlying conduction slowing and arrhythmogenesis in nonischemic dilated cardiomyopathy

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https://pubmed.ncbi.nlm.nih.gov/22252313

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced content of connexin43 gap junctions in ventricular myocardium from hypertrophied and ischemic human hearts

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/22252313

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Remodeling of myocyte gap junctions in arrhythmogenic right ventricular cardiomyopathy due to a deletion in plakoglobin (Naxos disease)

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stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/22252313

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Upregulation of gamma-catenin compensates for the loss of beta-catenin in adult cardiomyocytes

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/22252313

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Arrhythmogenic right ventricular cardiomyopathy

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/22252313

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Arrhythmogenic cardiomyopathy and abnormalities of cell-to-cell coupling

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stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/22252313

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

DOI

10.1128/MCB.06188-11

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PMC publication ID

3295003

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PubMed publication ID

22252313

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