Induction of neurite outgrowth in PC12 cells by alpha -phenyl-N-tert-butylnitron through activation of protein kinase C and the Ras-extracellular signal-regulated kinase pathway (Q28204706)

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scientific article (publication date: 31 August 2001)

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English	Induction of neurite outgrowth in PC12 cells by alpha -phenyl-N-tert-butylnitron through activation of protein kinase C and the Ras-extracellular signal-regulated kinase pathway	scientific article (publication date: 31 August 2001)

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9 November 2019

Induction of neurite outgrowth in PC12 cells by alpha -phenyl-N-tert-butylnitron through activation of protein kinase C and the Ras-extracellular signal-regulated kinase pathway (English)

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9 November 2019

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9 November 2019

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M Tsuji

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9 November 2019

M Kuwabara

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3 July 2001

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9 November 2019

Journal of Biological Chemistry

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9 November 2019

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9 November 2019

35

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9 November 2019

32779-32785

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9 November 2019

Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor

1 reference

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Mouse semaphorin H induces PC12 cell neurite outgrowth activating Ras-mitogen-activated protein kinase signaling pathway via Ca(2+) influx.

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Characterization of a novel fungal protein, p15, which induces neuronal differentiation of PC12 cells

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The trk Proto-Oncogene Product: a Signal Transducing Receptor for Nerve Growth Factor

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Tyrosine phosphorylation and tyrosine kinase activity of the trk proto-oncogene product induced by NGF.

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Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases

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Guanine-nucleotide-releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling

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Evidence for a Ras-dependent extracellular signal-regulated protein kinase (ERK) cascade

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ras mediates nerve growth factor receptor modulation of three signal-transducing protein kinases: MAP kinase, Raf-1, and RSK

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Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells

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Reversal of age-related increase in brain protein oxidation, decrease in enzyme activity, and loss in temporal and spatial memory by chronic administration of the spin-trapping compound N-tert-butyl-alpha-phenylnitrone.

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The Free Radical Trapping Agent N-Tert.-Butyl-α-Phenylnitrone (PBN) Attenuates Cerebral Ischaemic Injury in Gerbils

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Requirement of p38 mitogen-activated protein kinase for neuronal differentiation in PC12 cells

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Neurotrophins induce release of neurotrophins by the regulated secretory pathway

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Trk receptors use redundant signal transduction pathways involving SHC and PLC-gamma 1 to mediate NGF responses

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Activation of mitogen-activated protein kinase by H2O2. Role in cell survival following oxidant injury

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Neurite outgrowth induced by a synthetic peptide ligand of neural cell adhesion molecule requires fibroblast growth factor receptor activation

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The molecular heterogeneity of protein kinase C and its implications for cellular regulation

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Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C

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Protein kinase C isozymes that mediate enhancement of neurite outgrowth by ethanol and phorbol esters in PC12 cells.

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Nerve growth factor-induced neuronal differentiation of PC12 pheochromocytoma cells: lack of inhibition by a tumor promoter

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Suppression of nerve growth factor-induced neuronal differentiation of PC12 cells. N-acetylcysteine uncouples the signal transduction from ras to the mitogen-activated protein kinase cascade.

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Interactions of superoxide anion with enzyme radicals: kinetics of reaction with lysozyme tryptophan radicals and corresponding effects on tyrosine electron transfer

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The cysteine-rich regions of the regulatory domains of Raf and protein kinase C as retinoid receptors

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Redox regulation of cell signalling

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The selective and inducible activation of endogenous PI 3-kinase in PC12 cells results in efficient NGF-mediated survival but defective neurite outgrowth

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Inhibition of MAP Kinase Kinase Blocks the Differentiation of PC-12 Cells Induced by Nerve Growth Factor

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Specific activation of the p38 mitogen-activated protein kinase signaling pathway and induction of neurite outgrowth in PC12 cells by bone morphogenetic protein-2

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21 January 2018

The 38-amino-acid form of pituitary adenylate cyclase-activating polypeptide induces neurite outgrowth in PC12 cells that is dependent on protein kinase C and extracellular signal-regulated kinase but not on protein kinase A, nerve growth factor rec

1 reference

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21 January 2018

Ras is essential for nerve growth factor- and phorbol ester-induced tyrosine phosphorylation of MAP kinases

1 reference

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21 January 2018

Expression of cytokines and activation of transcription factors in lipopolysaccharide-administered rats and their inhibition by phenyl N-tert-butylnitrone (PBN)

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Phenyl N-tert-butylnitrone provides protection from endotoxin shock through amplified production of the anti-inflammatory cytokine interleukin-10

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Identifiers

10.1074/JBC.M101403200

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11438521%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11438521%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

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