PEDF: a multifaceted neurotrophic factor (Q28191537)

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6 November 2019

review article

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title

PEDF: a multifaceted neurotrophic factor (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12894238%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12894238%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

Joyce Tombran-Tink

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6 November 2019

language of work or name

English

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publication date

1 August 2003

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Nature Reviews Neuroscience

6 November 2019

published in

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6 November 2019

volume

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6 November 2019

issue

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6 November 2019

page(s)

628-636

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PEDF: a pigment epithelium-derived factor with potent neuronal differentiative activity

6 November 2019

cites work

1 reference

Expression, secretion, and age-related downregulation of pigment epithelium-derived factor, a serpin with neurotrophic activity

31 March 2020

1 reference

Sequence and expression analysis of bovine pigment epithelium-derived factor

31 March 2020

1 reference

Identification of pigment epithelium-derived factor in the interphotoreceptor matrix of bovine eyes

31 March 2020

1 reference

Molecular aspects of vertebrate retinal development.

31 March 2020

1 reference

Loss of the antiangiogenic pigment epithelium-derived factor in patients with angiogenic eye disease.

31 March 2020

1 reference

Crystal structure of human PEDF, a potent anti-angiogenic and neurite growth-promoting factor

31 March 2020

1 reference

Isolation, purification, and characterization of a collagen-associated serpin, caspin, produced by murine colon adenocarcinoma cells

31 March 2020

1 reference

Mapping the type I collagen-binding site on pigment epithelium-derived factor. Implications for its antiangiogenic activity

31 March 2020

1 reference

Pigment epithelium-derived factor (PEDF) binds to glycosaminoglycans: analysis of the binding site.

31 March 2020

1 reference

Pigment epithelium-derived factor (PEDF) protects motor neurons from chronic glutamate-mediated neurodegeneration

31 March 2020

1 reference

The neurotrophic factors in non-neuronal tissues

31 March 2020

1 reference

Localization of the gene for pigment epithelium-derived factor (PEDF) to chromosome 17p13.1 and expression in cultured human retinoblastoma cells

31 March 2020

1 reference

Pigment epithelium-derived factor: neurotrophic activity and identification as a member of the serine protease inhibitor gene family

31 March 2020

1 reference

Identification of the neuroprotective molecular region of pigment epithelium-derived factor and its binding sites on motor neurons.

31 March 2020

1 reference

Pigment epithelium-derived factor behaves like a noninhibitory serpin. Neurotrophic activity does not require the serpin reactive loop

31 March 2020

1 reference

Binding of pigment epithelium-derived factor (PEDF) to retinoblastoma cells and cerebellar granule neurons. Evidence for a PEDF receptor.

31 March 2020

1 reference

NFkappaB activation is required for the neuroprotective effects of pigment epithelium-derived factor (PEDF) on cerebellar granule neurons

31 March 2020

1 reference

Inducer-stimulated Fas targets activated endothelium for destruction by anti-angiogenic thrombospondin-1 and pigment epithelium-derived factor

31 March 2020

1 reference

NF-kappaB signals induce the expression of c-FLIP.

31 March 2020

1 reference

The caspase-8 inhibitor FLIP promotes activation of NF-kappaB and Erk signaling pathways

31 March 2020

1 reference

Tumor necrosis factors alpha and beta protect neurons against amyloid beta-peptide toxicity: evidence for involvement of a kappa B-binding factor and attenuation of peroxide and Ca2+ accumulation.

31 March 2020

1 reference

Inhibition of NF-kappaB potentiates amyloid beta-mediated neuronal apoptosis

31 March 2020

1 reference

Activation of NF-?B protects hippocampal neurons against oxidative stress-induced apoptosis: Evidence for induction of manganese superoxide dismutase and suppression of peroxynitrite production and protein tyrosine nitration

31 March 2020

1 reference

Nuclear factor-kappaB mediates the cell survival-promoting action of activity-dependent neurotrophic factor peptide-9

31 March 2020

1 reference

High constitutive NF-kappaB activity mediates resistance to oxidative stress in neuronal cells.

31 March 2020

1 reference

NF-kappaB functions as both a proapoptotic and antiapoptotic regulatory factor within a single cell type

31 March 2020

1 reference

Regulation of FasL by NF-κB and AP-1 in Fas-dependent Thymineless Death of Human Colon Carcinoma Cells

31 March 2020

1 reference

Neuroprotection by aspirin and sodium salicylate through blockade of NF-kappaB activation.

31 March 2020

1 reference

Differential induction of NF-kappaB activity and neural cell death by antidepressants in vitro

31 March 2020

1 reference

Induction of NF-kappaB activity during haloperidol-induced oxidative toxicity in clonal hippocampal cells: suppression of NF-kappaB and neuroprotection by antioxidants.

31 March 2020

1 reference

NF-kappa B-dependent Fas ligand expression

31 March 2020

1 reference

Activation-dependent transcriptional regulation of the human Fas promoter requires NF-kappaB p50-p65 recruitment

31 March 2020

1 reference

Regulation of fas-ligand expression during activation-induced cell death in T lymphocytes via nuclear factor kappaB.

31 March 2020

1 reference

T cell activation-induced and HIV tat-enhanced CD95(APO-1/Fas) ligand transcription involves NF-kappaB

31 March 2020

1 reference

Pigment epithelium-derived factor is a survival factor for cerebellar granule cells in culture

31 March 2020

1 reference

Pigment epithelium-derived factor promotes the survival and differentiation of developing spinal motor neurons

31 March 2020

1 reference

Multiple growth factors, cytokines, and neurotrophins rescue photoreceptors from the damaging effects of constant light

31 March 2020

1 reference

Photoreceptor outer segment development in Xenopus laevis: influence of the pigment epithelium

31 March 2020

1 reference

Pigment epithelium-derived factor supports normal development of photoreceptor neurons and opsin expression after retinal pigment epithelium removal

31 March 2020

1 reference

Pigment epithelium-derived factor delays the death of photoreceptors in mouse models of inherited retinal degenerations

31 March 2020

1 reference

Pigment epithelium derived factor as a neuroprotective agent against ischemic retinal injury

31 March 2020

1 reference

Pigment epithelium-derived factor supports normal Müller cell development and glutamine synthetase expression after removal of the retinal pigment epithelium

31 March 2020

1 reference

Pigment epithelium-derived factor (PEDF) has direct effects on the metabolism and proliferation of microglia and indirect effects on astrocytes

31 March 2020

1 reference

Pedf (Pigment epithelium-derived Factor) promotes increase and maturation of pigment granules in pigment epithelial cells in neonatal albino rat retinal cultures

31 March 2020

1 reference

Pigment epithelium-derived factor: a potent inhibitor of angiogenesis

31 March 2020

1 reference

Pigment epithelium-derived factor in the vitreous is low in diabetic retinopathy and high in rhegmatogenous retinal detachment

31 March 2020

1 reference

Pigment epithelium-derived factor is deficient in the vitreous of patients with choroidal neovascularization due to age-related macular degeneration.

31 March 2020

1 reference

Inverse levels of pigment epithelium-derived factor and vascular endothelial growth factor in the vitreous of eyes with rhegmatogenous retinal detachment and proliferative vitreoretinopathy

31 March 2020

1 reference

Novel mechanism for age-related macular degeneration: an equilibrium shift between the angiogenesis factors VEGF and PEDF.

31 March 2020

1 reference

Unbalanced vitreous levels of pigment epithelium-derived factor and vascular endothelial growth factor in diabetic retinopathy

31 March 2020

1 reference

Unbalanced expression of VEGF and PEDF in ischemia-induced retinal neovascularization

31 March 2020

1 reference

Upregulation of pigment epithelium-derived factor after laser photocoagulation

31 March 2020

1 reference

Pigment epithelium-derived factor is elevated in CSF of patients with amyotrophic lateral sclerosis

31 March 2020

1 reference

Identification of Proteins Differentially Expressed in Quiescent and Proliferatively Senescent Fibroblast Cultures

31 March 2020

1 reference

Regulation of EPC-1/PEDF in normal human fibroblasts is posttranscriptional.

31 March 2020

1 reference

Extension of cell life-span and telomere length in animals cloned from senescent somatic cells

31 March 2020

1 reference

Intratumoral gene therapy of malignant brain tumor in a rat model with angiostatin delivered by adeno-associated viral (AAV) vector

31 March 2020

1 reference

Anti-angiogenic treatment strategies for malignant brain tumors

31 March 2020

1 reference

Combined effects of radiotherapy and angiostatin gene therapy in glioma tumor model

31 March 2020

1 reference

Adeno-associated virus type-2 expression of pigmented epithelium-derived factor or Kringles 1-3 of angiostatin reduce retinal neovascularization

31 March 2020

1 reference

Autologous transplantation of genetically modified iris pigment epithelial cells: a promising concept for the treatment of age-related macular degeneration and other disorders of the eye.

31 March 2020

1 reference

Cyclin-dependent kinase 4 and cyclin D1 are required for excitotoxin-induced neuronal cell death in vivo.

31 March 2020

1 reference

Neurons in Alzheimer disease emerge from senescence

31 March 2020

1 reference

Cdc2 phosphorylation of BAD links the cell cycle to the cell death machinery

31 March 2020

1 reference

Cycling at the interface between neurodevelopment and neurodegeneration

31 March 2020

1 reference

Pigment epithelium–derived factor regulates the vasculature and mass of the prostate and pancreas

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NRN1176

2 references

Consolidated OpenCitations Corpus – April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12894238%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

6 November 2019

1026909827

0 references

1 reference

Consolidated OpenCitations Corpus – April 2017

2 references

Consolidated OpenCitations Corpus – April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12894238%20AND%20SRC:MED&resulttype=core&format=json