Parkinson's disease-associated mutant VPS35 causes mitochondrial dysfunction by recycling DLP1 complexes (Q28115112)

3 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26618722%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

title

Parkinson's disease-associated mutant VPS35 causes mitochondrial dysfunction by recycling DLP1 complexes (English)

2 references

3 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26618722%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

1 reference

mitochondrion-derived vesicle

1 reference

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:0099073

mitochondrial membrane scission site

1 reference

Gene Ontology release 2020-05-02

1 reference

GOA release 2020-03-11

VPS35 retromer complex component

1 reference

GOA release 2020-03-11

1 reference

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26618722%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26618722%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26618722%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Wenzhang Wang

2 references

3 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26618722%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Xinglong Wang

2 references

3 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26618722%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Hisashi Fujioka

2 references

3 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26618722%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Charles Hoppel

2 references

3 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26618722%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Jun Liu

2 references

3 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26618722%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Xiongwei Zhu

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26618722%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

language of work or name

English

0 references

publication date

30 November 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26618722%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

2 references

3 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26618722%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

2 references

3 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26618722%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

2 references

3 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26618722%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

page(s)

54-63

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26618722%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

1 March 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4826611/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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LRRK2 regulates mitochondrial dynamics and function through direct interaction with DLP1

20 March 2017

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1 reference

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Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

20 March 2017

1 reference

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1 reference

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A mutation in VPS35, encoding a subunit of the retromer complex, causes late-onset Parkinson disease

20 March 2017

1 reference

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20 March 2017

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Mechanism of neuroprotective mitochondrial remodeling by PKA/AKAP1

20 March 2017

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Parkin and PINK1 function in a vesicular trafficking pathway regulating mitochondrial quality control

20 March 2017

1 reference

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A Novel Dynamin-like Protein Associates with Cytoplasmic Vesicles and Tubules of the Endoplasmic Reticulum in Mammalian Cells

20 March 2017

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Mitochondrial defects and oxidative stress in Alzheimer disease and Parkinson disease

20 March 2017

1 reference

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PINK1-phosphorylated mitofusin 2 is a Parkin receptor for culling damaged mitochondria

20 March 2017

1 reference

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Impaired balance of mitochondrial fission and fusion in Alzheimer's disease

20 March 2017

1 reference

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Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin

20 March 2017

1 reference

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Disturbed mitochondrial dynamics and neurodegenerative disorders

7 April 2017

1 reference

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A new pathway for mitochondrial quality control: mitochondrial-derived vesicles

29 September 2017

1 reference

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Retromer binding to FAM21 and the WASH complex is perturbed by the Parkinson disease-linked VPS35(D620N) mutation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826611

Mutation in VPS35 associated with Parkinson's disease impairs WASH complex association and inhibits autophagy

29 September 2017

1 reference

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Parkinson's disease-linked mutations in VPS35 induce dopaminergic neurodegeneration

29 September 2017

1 reference

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29 September 2017

1 reference

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The Vps35 D620N mutation linked to Parkinson's disease disrupts the cargo sorting function of retromer

29 September 2017

1 reference

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Microglial beclin 1 regulates retromer trafficking and phagocytosis and is impaired in Alzheimer's disease

29 September 2017

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29 September 2017

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Reconstitution of mitochondria derived vesicle formation demonstrates selective enrichment of oxidized cargo

29 September 2017

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A multi-centre clinico-genetic analysis of the VPS35 gene in Parkinson disease indicates reduced penetrance for disease-associated variants

29 September 2017

1 reference

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29 September 2017

1 reference

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29 September 2017

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Parkinson's disease-associated DJ-1 mutations impair mitochondrial dynamics and cause mitochondrial dysfunction

29 September 2017

1 reference

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

1 reference

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Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics

29 September 2017

1 reference

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Vps35 mediates vesicle transport between the mitochondria and peroxisomes

29 September 2017

1 reference

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Translocation of SenP5 from the nucleoli to the mitochondria modulates DRP1-dependent fission during mitosis

29 September 2017

1 reference

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29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826611

Amyloid-beta overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826611

Dynamin-like protein 1 reduction underlies mitochondrial morphology and distribution abnormalities in fibroblasts from sporadic Alzheimer's disease patients

29 September 2017

1 reference

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Chemical inhibition of the mitochondrial division dynamin reveals its role in Bax/Bak-dependent mitochondrial outer membrane permeabilization

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826611

Mitochondrial fusion and fission in mammals

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826611

The mitochondrial elongation factors MIEF1 and MIEF2 exert partially distinct functions in mitochondrial dynamics.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826611

Frequency of the D620N mutation in VPS35 in Parkinson disease

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826611

A vesicular transport pathway shuttles cargo from mitochondria to lysosomes.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826611

Control of mitochondrial integrity in Parkinson's disease

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826611

Intra- and intermolecular domain interactions of the C-terminal GTPase effector domain of the multimeric dynamin-like GTPase Drp1.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826611

Identification of VPS35 mutations replicated in French families with Parkinson disease

27 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/26618722

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A stable lead by modification of Sato's method

1 reference

https://pubmed.ncbi.nlm.nih.gov/26618722

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NM.3983

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26618722%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26618722%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26618722%20AND%20SRC:MED&resulttype=core&format=json