Targeting Strategies for Renal Cell Carcinoma: From Renal Cancer Cells to Renal Cancer Stem Cells (Q28078154)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27891093%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

review article

1 reference

title

Targeting Strategies for Renal Cell Carcinoma: From Renal Cancer Cells to Renal Cancer Stem Cells (English)

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27891093%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

main subject

neoplastic stem cells

1 reference

1 reference

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27891093%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

Guixian Zhao

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27891093%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

Gang Shu

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27891093%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

Wei Zhao

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27891093%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

Zhi-Xiang Yuan

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27891093%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

Hua-Lin Fu

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27891093%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

language of work or name

1 reference

10 November 2016

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27891093%20AND%20SRC:MED&resulttype=core&format=json

Frontiers in Pharmacology

28 March 2020

published in

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27891093%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27891093%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

page(s)

423

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27891093%20AND%20SRC:MED&resulttype=core&format=json

Drug Delivery Using Nanoparticles for Cancer Stem-Like Cell Targeting

28 March 2020

cites work

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20 March 2017

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20 March 2017

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20 March 2017

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CD44: from adhesion molecules to signalling regulators

20 March 2017

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Cancer stem cells in solid tumours: accumulating evidence and unresolved questions

20 March 2017

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Aldehyde dehydrogenase 1 identifies cells with cancer stem cell-like properties in a human renal cell carcinoma cell line

20 March 2017

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Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells

20 March 2017

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Efficacy of everolimus in advanced renal cell carcinoma: a double-blind, randomised, placebo-controlled phase III trial

7 April 2017

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Efficacy of the nanoparticle-drug conjugate CRLX101 in combination with bevacizumab in metastatic renal cell carcinoma: results of an investigator-initiated phase I-IIa clinical trial

7 April 2017

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Preclinical effects of CRLX101, an investigational camptothecin-containing nanoparticle drug conjugate, on treating glioblastoma multiforme via apoptosis and antiangiogenesis

29 September 2017

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Anti-tumor effect via passive anti-angiogenesis of PEGylated liposomes encapsulating doxorubicin in drug resistant tumors.

29 September 2017

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A phase 1 study of buparlisib and bevacizumab in patients with metastatic renal cell carcinoma progressing on vascular endothelial growth factor-targeted therapies

29 September 2017

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A Randomized, Open-Label Phase 2 Study of the CXCR4 Inhibitor LY2510924 in Combination with Sunitinib Versus Sunitinib Alone in Patients with Metastatic Renal Cell Carcinoma (RCC).

29 September 2017

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Synergistic roles of p53 and HIF1α in human renal cell carcinoma-cell apoptosis responding to the inhibition of mTOR and MDM2 signaling pathways

29 September 2017

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Infiltration of tumor-associated macrophages is involved in CD44 expression in clear cell renal cell carcinoma

29 September 2017

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PI3K/Akt/mTOR and Ras/Raf/MEK/ERK signaling pathways inhibitors as anticancer agents: Structural and pharmacological perspectives

29 September 2017

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Dnajb8, a Member of the Heat Shock Protein 40 Family Has a Role in the Tumor Initiation and Resistance to Docetaxel but Is Dispensable for Stress Response

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Targeting CD133(+) laryngeal carcinoma cells with chemotherapeutic drugs and siRNA against ABCG2 mediated by thermo/pH-sensitive mesoporous silica nanoparticles

29 September 2017

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Downregulation of cancer stem cell properties via mTOR signaling pathway inhibition by rapamycin in nasopharyngeal carcinoma

29 September 2017

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Inactivation of bone morphogenetic protein 2 may predict clinical outcome and poor overall survival for renal cell carcinoma through epigenetic pathways

29 September 2017

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PIK3R1 negatively regulates the epithelial-mesenchymal transition and stem-like phenotype of renal cancer cells through the AKT/GSK3β/CTNNB1 signaling pathway

29 September 2017

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Future perspectives for mTOR inhibitors in renal cell cancer treatment

29 September 2017

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DCLK1 is a broadly dysregulated target against epithelial-mesenchymal transition, focal adhesion, and stemness in clear cell renal carcinoma

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Endoglin for targeted cancer treatment

29 September 2017

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29 September 2017

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The chemokine system, and its CCR5 and CXCR4 receptors, as potential targets for personalized therapy in cancer

29 September 2017

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29 September 2017

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29 September 2017

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PKI-587 and sorafenib alone and in combination on inhibition of liver cancer stem cell proliferation

29 September 2017

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Targeted therapy aimed at cancer stem cells: Wilms' tumor as an example

29 September 2017

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CXC chemokine receptor 4 is essential for maintenance of renal cell carcinoma-initiating cells and predicts metastasis.

29 September 2017

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Targeting the PI3K/AKT/mTOR signaling pathway in glioblastoma: novel therapeutic agents and advances in understanding

29 September 2017

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The Role of chemokine receptor CXCR4 in breast cancer metastasis

29 September 2017

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The isolation and characterization of renal cancer initiating cells from human Wilms' tumour xenografts unveils new therapeutic targets

29 September 2017

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In vivo inhibition of bone morphogenetic protein-2 on breast cancer cell growth

29 September 2017

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Tyrosine kinase inhibitors: views of selectivity, sensitivity, and clinical performance

29 September 2017

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High expression of CXCR4, CXCR7 and SDF-1 predicts poor survival in renal cell carcinoma

29 September 2017

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Interleukin-15 is a major regulator of the cell-microenvironment interactions in human renal homeostasis.

29 September 2017

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Silencing of CXCR4 by RNA interference inhibits cell growth and metastasis in human renal cancer cells

29 September 2017

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CD133 as a biomarker for putative cancer stem cells in solid tumours: limitations, problems and challenges

29 September 2017

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High-level expression of stem cell marker CD133 in clear cell renal cell carcinoma with favorable prognosis

29 September 2017

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Antibody-drug conjugates: using monoclonal antibodies for delivery of cytotoxic payloads to cancer cells.

29 September 2017

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A phase I first-in-human study of TRC105 (Anti-Endoglin Antibody) in patients with advanced cancer

29 September 2017

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The microRNA-17-92 family of microRNA clusters in development and disease

29 September 2017

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Human renal cancer stem cells

29 September 2017

1 reference

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HSP DNAJB8 controls tumor-initiating ability in renal cancer stem-like cells.

29 September 2017

1 reference

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CXCR7: a novel tumor endothelial marker in renal cell carcinoma

29 September 2017

1 reference

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Antitumor effect of the mTOR inhibitor everolimus in combination with trastuzumab on human breast cancer stem cells in vitro and in vivo

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103413

High CXCR4 expression correlates with sunitinib poor response in metastatic renal cancer.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103413

Interleukin-15 plays a central role in human kidney physiology and cancer through the γc signaling pathway.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103413

Antiangiogenic therapy for advanced renal cell carcinoma: management of treatment-related toxicities

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103413

BMP-2 inhibits tumor growth of human renal cell carcinoma and induces bone formation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103413

Phase I trial of everolimus plus sorafenib for patients with advanced renal cell cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103413

Molecular aspects of renal cell carcinoma: a review

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103413

MicroRNA regulation of cancer stem cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103413

Pharmacogenomics and cancer stem cells: a changing landscape?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103413

The cancer stem cell: premises, promises and challenges

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103413

Safety (toxicity), pharmacokinetics, immunogenicity, and impact on elements of the normal immune system of recombinant human IL-15 in rhesus macaques

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103413

Isolation and characterization of progenitor-like cells from human renal proximal tubules

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103413

The therapy of kidney cancer with biomolecular drugs.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103413

Endoglin-Targeted Cancer Therapy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103413

Selective targeting of neuroblastoma tumour-initiating cells by compounds identified in stem cell-based small molecule screens

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103413

EAU guidelines on renal cell carcinoma: the 2010 update

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103413

Characterizing cancer cells with cancer stem cell-like features in 293T human embryonic kidney cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103413

Interleukin-21: updated review of Phase I and II clinical trials in metastatic renal cell carcinoma, metastatic melanoma and relapsed/refractory indolent non-Hodgkin's lymphoma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103413

Hyaluronan-CD44 Interactions in Cancer: Paradoxes and Possibilities

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103413

Differential destruction of stem cells: implications for targeted cancer stem cell therapy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103413

Characterization of the Hoechst 33342 side population from normal and malignant human renal epithelial cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103413

Endoglin (CD105): a marker of tumor vasculature and potential target for therapy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103413

Intrinsic epithelial cells repair the kidney after injury

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103413

Novel SN-38-incorporated polymeric micelle, NK012, strongly suppresses renal cancer progression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103413

Do stem cells exist in the adult kidney?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103413

Hit 'em where they live: targeting the cancer stem cell niche

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103413

CD133+ renal progenitor cells contribute to tumor angiogenesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103413

Trafficking of normal stem cells and metastasis of cancer stem cells involve similar mechanisms: pivotal role of the SDF-1-CXCR4 axis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103413

Isolation of renal progenitor cells from adult human kidney

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103413

Cytokines in cancer pathogenesis and cancer therapy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103413

The essential roles of the chemokine SDF-1 and its receptor CXCR4 in human stem cell homing and repopulation of transplanted immune-deficient NOD/SCID and NOD/SCID/B2m(null) mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103413

IL-15, a survival factor for kidney epithelial cells, counteracts apoptosis and inflammation during nephritis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103413

Interleukins. Clinical pharmacology and therapeutic use.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103413

ROS links glucose metabolism to breast cancer stem cell and EMT phenotype

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103413

Resident stem cells and renal carcinoma

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103413

Opposing microRNA families regulate self-renewal in mouse embryonic stem cells

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103413

The Heidelberg classification of renal cell tumours

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5103413

Complete remission with tyrosine kinase inhibitors in renal cell carcinoma.

20 June 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2016.00423

Cancer risk after use of recombinant bone morphogenetic protein-2 for spinal arthrodesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2016.00423

Sequential use of the tyrosine kinase inhibitors sorafenib and sunitinib in metastatic renal cell carcinoma: a retrospective outcome analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2016.00423

Pharmacodynamic and pharmacogenomic study of the nanoparticle conjugate of camptothecin CRLX101 for the treatment of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2016.00423

Isolation and Characterization of Kidney-Derived Stem Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2016.00423

Cancer stem-like cell marker CD44 promotes bone metastases by enhancing tumorigenicity, cell motility, and hyaluronan production

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2016.00423

PI3K/mTOR dual inhibitor VS-5584 preferentially targets cancer stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2016.00423

Sustained inhibition of cMET-VEGFR2 signaling using liposome-mediated delivery increases efficacy and reduces toxicity in kidney cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2016.00423

Temsirolimus in metastatic renal cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2016.00423

Randomized phase III trial of temsirolimus and bevacizumab versus interferon alfa and bevacizumab in metastatic renal cell carcinoma: INTORACT trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2016.00423

Cancer statistics for Hispanics/Latinos, 2015.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2016.00423

Endoglin (CD105) expression in human renal cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2016.00423

Differentiation Therapy: Targeting Human Renal Cancer Stem Cells with Interleukin 15

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2016.00423

Identification of a tumor-initiating stem cell population in human renal carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2016.00423

CXCR4 expression in patients with high-risk locally advanced renal cell carcinoma can independently predict increased risk of disease progression and poor overall survival

21 January 2018

1 reference

12 December 2020

Clinical significances and prognostic value of cancer stem-like cells markers and vasculogenic mimicry in renal cell carcinoma

1 reference

12 December 2020

Prognostic role of CD44 cell adhesion molecule expression in primary and metastatic renal cell carcinoma: a clinicopathologic study of 125 cases

1 reference

12 December 2020

CD133 immunohistochemical expression predicts progression and cancer-related death in renal cell carcinoma

1 reference

12 December 2020

Studies evaluating the antitumor activity and toxicity of interleukin-15, a new T cell growth factor: comparison with interleukin-2

1 reference

12 December 2020

Constitutive and IFN-gamma regulated expression of IL-7 and IL-15 in human renal cell cancer

1 reference

12 December 2020

Identifiers

DOI

10.3389/FPHAR.2016.00423

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27891093%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27891093%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

PubMed publication ID

27891093

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27891093%20AND%20SRC:MED&resulttype=core&format=json