Adrenaline-activated structure of β2-adrenoceptor stabilized by an engineered nanobody (Q27680016)

object named as

Aashish Manglik

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author name string

Andrew C Kruse

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Michael D Enos

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K Christopher Garcia

N-Terminal T4 Lysozyme Fusion Facilitates Crystallization of a G Protein Coupled Receptor

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language of work or name

English

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publication date

24 October 2013

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published in

Nature

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volume

502

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issue

7472

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page(s)

575-9

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cites work

1 reference

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Stabilized G protein binding site in the structure of constitutively active metarhodopsin-II

20 March 2017

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Crystal structure of the β2 adrenergic receptor-Gs protein complex

20 March 2017

1 reference

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Agonist-bound adenosine A2A receptor structures reveal common features of GPCR activation

20 March 2017

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Structure of an agonist-bound human A2A adenosine receptor

20 March 2017

1 reference

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The structural basis for agonist and partial agonist action on a β(1)-adrenergic receptor

20 March 2017

1 reference

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Structure and function of an irreversible agonist-β(2) adrenoceptor complex

20 March 2017

1 reference

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Structure of a nanobody-stabilized active state of the β(2) adrenoceptor

20 March 2017

1 reference

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Structure of a beta1-adrenergic G-protein-coupled receptor

20 March 2017

1 reference

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Towards automated crystallographic structure refinement with phenix.refine

20 March 2017

1 reference

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Phasercrystallographic software

20 March 2017

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Coot: model-building tools for molecular graphics

20 March 2017

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Crystallizing membrane proteins using lipidic mesophases

20 March 2017

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Molecular signatures of G-protein-coupled receptors

7 April 2017

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The dynamic process of β(2)-adrenergic receptor activation

29 September 2017

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Highly conserved tyrosine stabilizes the active state of rhodopsin

29 September 2017

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Conformational thermostabilization of the beta1-adrenergic receptor in a detergent-resistant form

29 September 2017

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A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein

29 September 2017

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Isolating and engineering human antibodies using yeast surface display

29 September 2017

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A new yeast display vector permitting free scFv amino termini can augment ligand binding affinities

29 September 2017

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The forgotten serine. A critical role for Ser-2035.42 in ligand binding to and activation of the beta 2-adrenergic receptor.

29 September 2017

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Amino and carboxyl terminal modifications to facilitate the production and purification of a G protein-coupled receptor

29 September 2017

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Conserved Tyr223(5.58) plays different roles in the activation and G-protein interaction of rhodopsin.

2 June 2018

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Impact of the DRY motif and the missing "ionic lock" on constitutive activity and G-protein coupling of the human histamine H4 receptor

27 November 2018

1 reference

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Identification of two serine residues involved in agonist activation of the beta-adrenergic receptor

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24056936

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Processing of X-ray diffraction data collected in oscillation mode

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24056936

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NATURE12572

1 reference

Dimensions Publication ID

1049108516

0 references

1 reference

1 reference

PubMed publication ID

24056936

1 reference