Structural Basis for Molecular Recognition at Serotonin Receptors (Q27676926)

John D McCorvy

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Bryan L. Roth

Bryan L Roth

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Gye Won Han

Gye Won Han

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Eyal Vardy

Eyal Vardy

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Chenghai Zhang

Chenghai Zhang

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Wei Liu

Wei Liu

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author name string

Chong Wang

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Yi Jiang

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Jinming Ma

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Xi-Ping Huang

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Xiang Gao

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X Edward Zhou

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Huaiyu Yang

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Linlin Yang

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H Eric Xu

Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist

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language of work or name

English

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publication date

3 May 2013

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published in

Science

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volume

340

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issue

6132

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page(s)

610-4

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cites work

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20 March 2017

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Molecular determinants for the interaction of the valvulopathic anorexigen norfenfluramine with the 5-HT2B receptor

20 March 2017

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Evidence for possible involvement of 5-HT(2B) receptors in the cardiac valvulopathy associated with fenfluramine and other serotonergic medications

20 March 2017

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International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (Serotonin)

20 March 2017

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Structural Features for Functional Selectivity at Serotonin Receptors

20 March 2017

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Structure of the Human Dopamine D3 Receptor in Complex with a D2/D3 Selective Antagonist

22 April 2017

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Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists

22 April 2017

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Toward the structural genomics of complexes: Crystal structure of a PE/PPE protein complex from Mycobacterium tuberculosis

22 April 2017

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22 April 2017

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29 September 2017

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Current and prospective pharmacological targets in relation to antimigraine action

29 September 2017

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Discovery and structure-activity relationship of (1R)-8-chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine (Lorcaserin), a selective serotonin 5-HT2C receptor agonist for the treatment of obesity

29 September 2017

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Serotonin receptors represent highly favorable molecular targets for cognitive enhancement in schizophrenia and other disorders

29 September 2017

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29 September 2017

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A single point mutation increases the affinity of serotonin 5-HT1D alpha, 5-HT1D beta, 5-HT1E and 5-HT1F receptors for beta-adrenergic antagonists

29 September 2017

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A single amino-acid difference confers major pharmacological variation between human and rodent 5-HT1B receptors

29 September 2017

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Migraine: pathophysiology, pharmacology, treatment and future trends.

2 June 2018

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Anorexogen-related cardiac valvulopathy

27 November 2018

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Pharmaceutical approval update

27 November 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/23519210

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Species differences in the pharmacology of the 5-hydroxytryptamine2 receptor: structurally specific differentiation by ergolines and tryptamines

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23519210

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Assessment of the roles of serines 5.43(239) and 5.46(242) for binding and potency of agonist ligands at the human serotonin 5-HT2A receptor

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23519210

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Phasercrystallographic software

1 reference

20 May 2022

https://opencitations.net/index/coci/api/v1/citations/10.1107/S0021889807021206

Epik: a software program for pK( a ) prediction and protonation state generation for drug-like molecules

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Identifiers

DOI

10.1126/SCIENCE.1232807

1 reference

ADS bibcode

2013Sci...340..610W

0 references

1 reference

1 reference

PubMed publication ID

23519210

1 reference