Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist (Q24628686)

0 references

Takami Yurugi-Kobayashi

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Mitsunori Shiroishi

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Tetsuji Okada

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Tatsuya Haga

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Takuya Kobayashi

Structure of the human histamine H1 receptor complex with doxepin

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language of work or name

English

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publication date

23 February 2012

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published in

Nature

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volume

482

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issue

7386

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page(s)

547-51

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cites work

1 reference

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Structure of a nanobody-stabilized active state of the β(2) adrenoceptor

7 April 2017

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Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists

7 April 2017

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The 2.6 angstrom crystal structure of a human A2A adenosine receptor bound to an antagonist

7 April 2017

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Crystal Structures of a Cysteine-modified Mutant in Loop D of Acetylcholine-binding Protein

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3345277

Structure of the Human Dopamine D3 Receptor in Complex with a D2/D3 Selective Antagonist

7 April 2017

1 reference

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Crystal structures of the choline/acetylcholine substrate-binding protein ChoX from Sinorhizobium meliloti in the liganded and unliganded-closed states

7 April 2017

1 reference

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Structure of a beta1-adrenergic G-protein-coupled receptor

7 April 2017

1 reference

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Crystal structure of rhodopsin: A G protein-coupled receptor

7 April 2017

1 reference

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Phasercrystallographic software

7 April 2017

1 reference

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Solving structures of protein complexes by molecular replacement with Phaser

7 April 2017

1 reference

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GPCR engineering yields high-resolution structural insights into beta2-adrenergic receptor function

7 April 2017

1 reference

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Crystallizing membrane proteins using lipidic mesophases

7 April 2017

1 reference

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A robust bulk-solvent correction and anisotropic scaling procedure

7 April 2017

1 reference

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Evaluation of the Pichia pastoris expression system for the production of GPCRs for structural analysis

26 May 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3345277

Muscarinic acetylcholine receptors: mutant mice provide new insights for drug development

27 September 2017

1 reference

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Scanning mutagenesis studies of the M1 muscarinic acetylcholine receptor

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3345277

Cation-pi interactions in ligand recognition and catalysis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3345277

Site-directed mutagenesis of the putative human muscarinic M2 receptor binding site

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3345277

Mutational analysis of muscarinic acetylcholine receptors: structural basis of ligand/receptor/G protein interactions

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3345277

Rhodopsin and bacteriorhodopsin: structure-function relationships

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3345277

Cloning, sequencing and expression of complementary DNA encoding the muscarinic acetylcholine receptor

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3345277

Cloning of the gene and cDNA for mammalian beta-adrenergic receptor and homology with rhodopsin

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3345277

Muscarinic receptor subtypes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3345277

Structural insights into substrate traffic and inhibition in acetylcholinesterase

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3345277

Activation of a GTP-binding protein and a GTP-binding-protein-coupled receptor kinase (beta-adrenergic-receptor kinase-1) by a muscarinic receptor m2 mutant lacking phosphorylation sites

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3345277

Optimisation of protein expression and establishment of the Wave Bioreactor for Baculovirus/insect cell culture

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3345277

Functional role in ligand binding and receptor activation of an asparagine residue present in the sixth transmembrane domain of all muscarinic acetylcholine receptors

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3345277

Affinity chromatography of the muscarinic acetylcholine receptor

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3345277

Purification of the muscarinic acetylcholine receptor from porcine brain

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3345277

Functional reconstitution of purified muscarinic receptors and inhibitory guanine nucleotide regulatory protein

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3345277

Allosteric modulation of muscarinic acetylcholine receptors

30 May 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10753

The structure of the third intracellular loop of the muscarinic acetylcholine receptor M2 subtype

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10753

Roof and floor of the muscarinic binding pocket: variations in the binding modes of orthosteric ligands.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10753

Conformation of ligands bound to the muscarinic acetylcholine receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10753

Processing of X-ray diffraction data collected in oscillation mode

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10753

Alanine-scanning mutagenesis of transmembrane domain 6 of the M(1) muscarinic acetylcholine receptor suggests that Tyr381 plays key roles in receptor function

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22278061

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NATURE10753

1 reference

Dimensions Publication ID

1031262339

0 references

Fatcat ID

release_qgopuho5p5hc7n5w3p3ajj25hi

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/qgopuho5p5hc7n5w3p3ajj25hi

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

1 reference

PubMed publication ID

22278061

1 reference