Structural Insight into the Mechanisms of Wnt Signaling Antagonism by Dkk (Q27650747)

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8 January 2020

title

Structural insight into the mechanisms of Wnt signaling antagonism by Dkk (English)

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8 January 2020

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8 January 2020

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8 January 2020

Lijun Chen

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8 January 2020

Ke Wang

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8 January 2020

Youming Shao

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8 January 2020

Xiaofeng Li

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8 January 2020

Jufang Shan

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8 January 2020

Dianqing Wu

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8 January 2020

language of work or name

English

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publication date

3 June 2008

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Journal of Biological Chemistry

8 January 2020

number of pages

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based on heuristic

inferred from page(s)

published in

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8 January 2020

volume

283

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8 January 2020

issue

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8 January 2020

page(s)

23364-23370

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Direct binding of the PDZ domain of Dishevelled to a conserved internal sequence in the C-terminal region of Frizzled

8 January 2020

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20 March 2017

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20 March 2017

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Regulation of Wnt/LRP signaling by distinct domains of Dickkopf proteins

20 March 2017

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Second cysteine-rich domain of Dickkopf-2 activates canonical Wnt signaling pathway via LRP-6 independently of dishevelled

20 March 2017

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Head inducer Dickkopf-1 is a ligand for Wnt coreceptor LRP6

20 March 2017

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Novel mechanism of Wnt signalling inhibition mediated by Dickkopf-1 interaction with LRP6/Arrow

20 March 2017

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Structural basis of the recognition of the dishevelled DEP domain in the Wnt signaling pathway

20 March 2017

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Functional and structural diversity of the human Dickkopf gene family

20 March 2017

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A structural homologue of colipase in black mamba venom revealed by NMR floating disulphide bridge analysis

20 March 2017

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20 March 2017

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20 March 2017

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20 March 2017

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Protein structure comparison by alignment of distance matrices

20 March 2017

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Kremen2 modulates Dickkopf2 activity during Wnt/LRP6 signaling

20 March 2017

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Kremen proteins are Dickkopf receptors that regulate Wnt/beta-catenin signalling

20 March 2017

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Colipase: structure and interaction with pancreatic lipase

20 March 2017

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Assessment of CAPRI predictions in rounds 3-5 shows progress in docking procedures

20 March 2017

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LRP6 expression promotes cancer cell proliferation and tumorigenesis by altering beta-catenin subcellular distribution

20 March 2017

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20 March 2017

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20 March 2017

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7 April 2017

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Function and biological roles of the Dickkopf family of Wnt modulators

7 April 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Folding of the N-terminal, ligand-binding region of integrin alpha-subunits into a beta-propeller domain

29 September 2017

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Derivation of rules for comparative protein modeling from a database of protein structure alignments

29 September 2017

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Disulphide bridges in globular proteins

29 September 2017

1 reference

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Efficient analysis of protein 2D NMR spectra using the software packageEASY

29 September 2017

1 reference

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Characterization of the Kremen-binding site on Dkk1 and elucidation of the role of Kremen in Dkk-mediated Wnt antagonism

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2517007

Dishevelled proteins lead to two signaling pathways. Regulation of LEF-1 and c-Jun N-terminal kinase in mammalian cells

2 June 2018

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2 June 2018

Identifiers

DOI

10.1074/JBC.M802375200

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18524778%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

1 reference

2 references

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8 January 2020

PubMed publication ID

18524778

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18524778%20AND%20SRC:MED&resulttype=core&format=json