Dual modes of modification of hepatitis A virus 3C protease by a serine-derived beta-lactone: selective crystallization and formation of a functional catalytic triad in the active site (Q34467806)

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English	Dual modes of modification of hepatitis A virus 3C protease by a serine-derived beta-lactone: selective crystallization and formation of a functional catalytic triad in the active site	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

2 August 2017

Dual modes of modification of hepatitis A virus 3C protease by a serine-derived beta-lactone: selective crystallization and formation of a functional catalytic triad in the active site (English)

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Europe PubMed Central

PubMed publication ID

2 August 2017

Hepatitis A virus

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inferred from title

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inferred from title

John Christopher Vederas

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John C Vederas

6

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author name string

Jiang Yin

1

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Europe PubMed Central

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2 August 2017

Ernst M Bergmann

2

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Europe PubMed Central

PubMed publication ID

2 August 2017

Maia M Cherney

3

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Europe PubMed Central

PubMed publication ID

2 August 2017

Manjinder S Lall

4

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Europe PubMed Central

PubMed publication ID

2 August 2017

Rajendra P Jain

5

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Europe PubMed Central

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2 August 2017

Michael N G James

7

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Europe PubMed Central

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2 August 2017

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publication date

14 October 2005

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Europe PubMed Central

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2 August 2017

Journal of Molecular Biology

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Europe PubMed Central

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2 August 2017

354

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Europe PubMed Central

PubMed publication ID

2 August 2017

4

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Europe PubMed Central

PubMed publication ID

2 August 2017

854-871

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Europe PubMed Central

PubMed publication ID

2 August 2017

Dengue virus NS3 serine protease. Crystal structure and insights into interaction of the active site with substrates by molecular modeling and structural analysis of mutational effects

1 reference

https://pubmed.ncbi.nlm.nih.gov/16288920

12 December 2020

based on heuristic

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Poliovirus RNA synthesis utilizes an RNP complex formed around the 5'-end of viral RNA.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16288920

12 December 2020

based on heuristic

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Structure of arterivirus nsp4. The smallest chymotrypsin-like proteinase with an alpha/beta C-terminal extension and alternate conformations of the oxyanion hole

1 reference

https://pubmed.ncbi.nlm.nih.gov/16288920

12 December 2020

based on heuristic

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ESPript: analysis of multiple sequence alignments in PostScript

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https://pubmed.ncbi.nlm.nih.gov/16288920

12 December 2020

based on heuristic

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Coronavirus main proteinase (3CLpro) structure: basis for design of anti-SARS drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/16288920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deduction of the 3C proteinases' fold

1 reference

https://pubmed.ncbi.nlm.nih.gov/16288920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Main-chain bond lengths and bond angles in protein structures

1 reference

https://pubmed.ncbi.nlm.nih.gov/16288920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional Dissection of a Poliovirus cis -Acting Replication Element [PV- cre (2C)]: Analysis of Single- and Dual- cre Viral Genomes and Proteins That Bind Specifically to PV- cre RNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/16288920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aromatic rings act as hydrogen bond acceptors

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https://pubmed.ncbi.nlm.nih.gov/16288920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serine and threonine beta-lactones: a new class of hepatitis A virus 3C cysteine proteinase inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/16288920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemical and genetic studies of the initiation of human rhinovirus 2 RNA replication: identification of a cis-replicating element in the coding sequence of 2A(pro).

1 reference

https://pubmed.ncbi.nlm.nih.gov/16288920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple sequence alignment with hierarchical clustering

1 reference

https://pubmed.ncbi.nlm.nih.gov/16288920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The CCP4 suite: programs for protein crystallography

1 reference

https://pubmed.ncbi.nlm.nih.gov/16288920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

XtalView/Xfit--A versatile program for manipulating atomic coordinates and electron density

1 reference

https://pubmed.ncbi.nlm.nih.gov/16288920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficient anisotropic refinement of macromolecular structures using FFT

1 reference

https://pubmed.ncbi.nlm.nih.gov/16288920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Refined X-ray crystallographic structure of the poliovirus 3C gene product 1 1Edited By D. Rees

1 reference

https://pubmed.ncbi.nlm.nih.gov/16288920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic evidence for an interaction between a picornaviral cis-acting RNA replication element and 3CD protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/16288920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure of human rhinovirus 3C protease reveals a trypsin-like polypeptide fold, RNA-binding site, and means for cleaving precursor polyprotein

1 reference

https://pubmed.ncbi.nlm.nih.gov/16288920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Substitutions in the protease (3Cpro) gene of poliovirus can suppress a mutation in the 5' noncoding region

1 reference

https://pubmed.ncbi.nlm.nih.gov/16288920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Picornaviral 3C cysteine proteinases have a fold similar to chymotrypsin-like serine proteinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/16288920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural basis for the substrate specificity of tobacco etch virus protease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16288920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The crystal structure of hepatitis C virus NS3 proteinase reveals a trypsin-like fold and a structural zinc binding site

1 reference

https://pubmed.ncbi.nlm.nih.gov/16288920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The refined crystal structure of the 3C gene product from hepatitis A virus: specific proteinase activity and RNA recognition

1 reference

https://pubmed.ncbi.nlm.nih.gov/16288920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. 2. Peptide structure-activity studies.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16288920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Why does threonine, and not serine, function as the active site nucleophile in proteasomes?

1 reference

https://pubmed.ncbi.nlm.nih.gov/16288920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Processing of X-ray diffraction data collected in oscillation mode

1 reference

https://pubmed.ncbi.nlm.nih.gov/16288920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepatitis A virus proteinase 3C binding to viral RNA: correlation with substrate binding and enzyme dimerization.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16288920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interactions of viral protein 3CD and poly(rC) binding protein with the 5' untranslated region of the poliovirus genome

1 reference

https://pubmed.ncbi.nlm.nih.gov/16288920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cleavage specificity of purified recombinant hepatitis A virus 3C proteinase on natural substrates.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16288920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The picornaviral 3C proteinases: cysteine nucleophiles in serine proteinase folds

1 reference

https://pubmed.ncbi.nlm.nih.gov/16288920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

wARP: improvement and extension of crystallographic phases by weighted averaging of multiple-refined dummy atomic models

1 reference

https://pubmed.ncbi.nlm.nih.gov/16288920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The lipase inhibitor tetrahydrolipstatin binds covalently to the putative active site serine of pancreatic lipase

1 reference

https://pubmed.ncbi.nlm.nih.gov/16288920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthesis and evaluation of keto-glutamine analogues as inhibitors of hepatitis A virus 3C proteinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/16288920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Solution structure of a consensus stem-loop D RNA domain that plays important roles in regulating translation and replication in enteroviruses and rhinoviruses

1 reference

https://pubmed.ncbi.nlm.nih.gov/16288920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Improved methods for building protein models in electron density maps and the location of errors in these models

1 reference

https://pubmed.ncbi.nlm.nih.gov/16288920

12 December 2020

based on heuristic

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A novel enantioselective synthetic route to omuralide analogues with the potential for species selectivity in proteasome inhibition

1 reference

https://pubmed.ncbi.nlm.nih.gov/16288920

12 December 2020

based on heuristic

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The crystal structures of severe acute respiratory syndrome virus main protease and its complex with an inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/16288920

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based on heuristic

inferred from PubMed ID database lookup

Beta-lactones as a new class of cysteine proteinase inhibitors: inhibition of hepatitis A virus 3C proteinase by N-Cbz-serine beta-lactone.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16288920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Foodborne outbreaks of hepatitis A in a low endemic country: an emerging problem?

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of the RNA binding and protein processing activities of poliovirus polypeptide 3CD by the viral RNA polymerase domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/16288920

12 December 2020

based on heuristic

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Structure of coronavirus main proteinase reveals combination of a chymotrypsin fold with an extra alpha-helical domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/16288920

12 December 2020

based on heuristic

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Crystal structure of foot-and-mouth disease virus 3C protease. New insights into catalytic mechanism and cleavage specificity

1 reference

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12 December 2020

based on heuristic

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Structure of 20S proteasome from yeast at 2.4 A resolution

1 reference

https://pubmed.ncbi.nlm.nih.gov/16288920

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based on heuristic

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Biochemical and genetic studies of the initiation of human rhinovirus 2 RNA replication: purification and enzymatic analysis of the RNA-dependent RNA polymerase 3D(pol).

1 reference

https://pubmed.ncbi.nlm.nih.gov/16288920

12 December 2020

based on heuristic

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Crystal structure of an inhibitor complex of the 3C proteinase from hepatitis A virus (HAV) and implications for the polyprotein processing in HAV

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.JMB.2005.09.074

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

PMC publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

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