Inhibition of Hedgehog signaling antagonizes serous ovarian cancer growth in a primary xenograft model (Q27311622)

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17 January 2020

title

Inhibition of Hedgehog signaling antagonizes serous ovarian cancer growth in a primary xenograft model (English)

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17 January 2020

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17 January 2020

Darrell R Borger

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17 January 2020

Christopher K McCann

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17 January 2020

Whitfield B Growdon

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17 January 2020

Kashmira Kulkarni-Datar

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Michael D Curley

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17 January 2020

Jennifer L Proctor

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17 January 2020

Hana Sheikh

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17 January 2020

Igor Deyneko

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17 January 2020

Jeanne A Ferguson

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17 January 2020

Vinod Vathipadiekal

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17 January 2020

Michael J Birrer

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17 January 2020

Gayatry Mohapatra

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Lawrence R Zukerberg

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Rosemary Foster

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John R Macdougall

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17 January 2020

Bo R Rueda

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language of work or name

English

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publication date

29 November 2011

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17 January 2020

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volume

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issue

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page(s)

e28077

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Creative Commons Attribution 4.0 International

17 January 2020

start time

29 November 2011

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April 2022 Public Data File from Crossref

copyrighted

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cites work

Hedgehog signaling in animal development: paradigms and principles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226669

The Hedgehog and Wnt signalling pathways in cancer

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226669

Discovery of a potent and orally active hedgehog pathway antagonist (IPI-926)

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226669

Human homolog of patched, a candidate gene for the basal cell nevus syndrome

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226669

21 March 2017

Cancer statistics, 2009

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226669

Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226669

Targeting Hedgehog--a cancer stem cell pathway

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226669

Activation of hedgehog signaling is not a frequent event in ovarian cancers

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226669

Role of hedgehog signaling in ovarian cancer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226669

Aberrant activation of hedgehog signaling pathway in ovarian cancers: effect on prognosis, cell invasion and differentiation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226669

A paracrine requirement for hedgehog signalling in cancer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226669

Hedgehog signaling pathway: development of antagonists for cancer therapy

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226669

Melanomas require HEDGEHOG-GLI signaling regulated by interactions between GLI1 and the RAS-MEK/AKT pathways.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226669

Targeted therapy for cancer stem cells: the patched pathway and ABC transporters

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226669

Shifting paradigms in Hedgehog signaling

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226669

Hedgehog signal pathway is activated in ovarian carcinomas, correlating with cell proliferation: it's inhibition leads to growth suppression and apoptosis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226669

The hedgehog signaling pathway in cancer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226669

Melanoma, a tumor based on a mutant stem cell?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226669

Targeting medulloblastoma: small-molecule inhibitors of the Sonic Hedgehog pathway as potential cancer therapeutics

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226669

Therapeutic targeting of the Hedgehog-GLI pathway in prostate cancer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226669

Inhibition of prostate cancer proliferation by interference with SONIC HEDGEHOG-GLI1 signaling

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226669

Hedgehog signaling: progenitor phenotype in small-cell lung cancer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226669

Medulloblastoma growth inhibition by hedgehog pathway blockade

28 September 2017

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0028077

Expression profiling of serous low malignant potential, low-grade, and high-grade tumors of the ovary.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0028077

CD133 expression defines a tumor initiating cell population in primary human ovarian cancer

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226669

Targeting the Hedgehog pathway in cancer

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22140510

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0028077

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22140510%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

ADS bibcode

2011PLoSO...628077M

0 references

1 reference

2 references

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17 January 2020

PubMed publication ID

22140510

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22140510%20AND%20SRC:MED&resulttype=core&format=json