Mutant TDP-43 and FUS cause age-dependent paralysis and neurodegeneration in C. elegans (Q27309039)

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English	Mutant TDP-43 and FUS cause age-dependent paralysis and neurodegeneration in C. elegans	scientific article

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instance of

scholarly article

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title

Mutant TDP-43 and FUS cause age-dependent paralysis and neurodegeneration in C. elegans (English)

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main subject

Caenorhabditis elegans

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neurodegeneration

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based on heuristic

inferred from title

author

Guy A. Rouleau

series ordinal

4

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Arnaud Tauffenberger

object named as

Arnaud Tauffenberger

series ordinal

2

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Alexandra Vaccaro

object named as

Alexandra Vaccaro

series ordinal

1

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Pierre Drapeau

series ordinal

5

object named as

Pierre Drapeau

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author name string

Dina Aggad

series ordinal

3

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J Alex Parker

series ordinal

6

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language of work or name

English

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publication date

2012

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published in

PLOS One

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volume

7

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issue

2

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page(s)

e31321

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copyright license

Creative Commons Attribution 4.0 International

start time

21 February 2012

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stated in

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

Mutations in UBQLN2 cause dominant X-linked juvenile and adult-onset ALS and ALS/dementia

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3283630

retrieved

21 March 2017

FUS and TARDBP but not SOD1 interact in genetic models of amyotrophic lateral sclerosis

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3283630

retrieved

21 March 2017

An ALS-linked mutant SOD1 produces a locomotor defect associated with aggregation and synaptic dysfunction when expressed in neurons of Caenorhabditis elegans

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3283630

retrieved

21 March 2017

Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3283630

retrieved

21 March 2017

TDP-43 and FUS in amyotrophic lateral sclerosis and frontotemporal dementia

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3283630

retrieved

21 March 2017

Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3283630

retrieved

21 March 2017

TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3283630

retrieved

21 March 2017

Identification and characterization of the vesicular GABA transporter

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3283630

retrieved

21 March 2017

TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3283630

retrieved

7 April 2017

Maintenance of C. elegans

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3283630

retrieved

7 April 2017

ALS: a disease of motor neurons and their nonneuronal neighbors

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3283630

retrieved

7 April 2017

Opposing activities protect against age-onset proteotoxicity

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3283630

retrieved

7 April 2017

ALS mutations in FUS cause neuronal dysfunction and death in Caenorhabditis elegans by a dominant gain-of-function mechanism

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3283630

retrieved

28 September 2017

The ALS-associated proteins FUS and TDP-43 function together to affect Drosophila locomotion and life span.

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3283630

retrieved

28 September 2017

Selective neuronal vulnerability in neurodegenerative diseases: from stressor thresholds to degeneration

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3283630

retrieved

28 September 2017

A yeast model of FUS/TLS-dependent cytotoxicity

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3283630

retrieved

28 September 2017

A Drosophila model of FUS-related neurodegeneration reveals genetic interaction between FUS and TDP-43.

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3283630

retrieved

28 September 2017

TDP-43 neurotoxicity and protein aggregation modulated by heat shock factor and insulin/IGF-1 signaling

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3283630

retrieved

28 September 2017

Phosphorylation Promotes Neurotoxicity in aCaenorhabditis elegansModel of TDP-43 Proteinopathy

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3283630

retrieved

28 September 2017

Amyotrophic lateral sclerosis-associated proteins TDP-43 and FUS/TLS function in a common biochemical complex to co-regulate HDAC6 mRNA.

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3283630

retrieved

28 September 2017

Coenzyme Q protects Caenorhabditis elegans GABA neurons from calcium-dependent degeneration

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3283630

retrieved

28 September 2017

ALS-associated mutations in TDP-43 increase its stability and promote TDP-43 complexes with FUS/TLS.

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3283630

retrieved

28 September 2017

Neurotoxic effects of TDP-43 overexpression in C. elegans

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3283630

retrieved

28 September 2017

TDP-43 and FUS/TLS: emerging roles in RNA processing and neurodegeneration

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3283630

retrieved

28 September 2017

A Drosophila model for TDP-43 proteinopathy

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3283630

retrieved

28 September 2017

Gain and loss of function of ALS-related mutations of TARDBP (TDP-43) cause motor deficits in vivo

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3283630

retrieved

28 September 2017

Genetics of motor neuron disorders: new insights into pathogenic mechanisms

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3283630

retrieved

28 September 2017

Mutations in FUS cause FALS and SALS in French and French Canadian populations

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3283630

retrieved

28 September 2017

A yeast TDP-43 proteinopathy model: Exploring the molecular determinants of TDP-43 aggregation and cellular toxicity

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3283630

retrieved

28 September 2017

The measurement and analysis of age-related changes in Caenorhabditis elegans

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3283630

retrieved

28 September 2017

Amyotrophic lateral sclerosis from bench to bedside

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3283630

retrieved

28 September 2017

Dietary restriction suppresses proteotoxicity and enhances longevity by an hsf-1-dependent mechanism in Caenorhabditis elegans

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3283630

retrieved

28 September 2017

TDP-43 A315T mutation in familial motor neuron disease

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3283630

retrieved

28 September 2017

Vigorous motor activity in Caenorhabditis elegans requires efficient clearance of dopamine mediated by synaptic localization of the dopamine transporter DAT-1.

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3283630

retrieved

28 September 2017

Immunohistochemistry

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3283630

retrieved

28 September 2017

GABA.

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3283630

retrieved

28 September 2017

Molecular biology of amyotrophic lateral sclerosis: insights from genetics

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3283630

retrieved

28 September 2017

The GABAergic nervous system of Caenorhabditis elegans

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3283630

retrieved

28 September 2017

Analysis of synaptic transmission in Caenorhabditis elegans using an aldicarb-sensitivity assay.

1 reference

stated in

Crossref

reference URL

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0031321

retrieved

21 January 2018

A conserved postsynaptic transmembrane protein affecting neuromuscular signaling in Caenorhabditis elegans.

1 reference

stated in

Crossref

reference URL

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0031321

retrieved

21 January 2018

An RNAi screen identifies genes that regulate GABA synapses

1 reference

stated in

Crossref

reference URL

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0031321

retrieved

21 January 2018

Pharmacologic reversal of cortical hyperexcitability in patients with ALS.

1 reference

stated in

Crossref

reference URL

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0031321

retrieved

21 January 2018

Cortical hyperexcitability may precede the onset of familial amyotrophic lateral sclerosis

1 reference

stated in

Crossref

reference URL

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0031321

retrieved

21 January 2018

Amyotrophic lateral sclerosis

1 reference

stated in

Crossref

reference URL

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0031321

retrieved

21 January 2018

Pathological hallmarks of amyotrophic lateral sclerosis/frontotemporal lobar degeneration in transgenic mice produced with TDP-43 genomic fragments

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3283630

retrieved

28 November 2018

Sirtuin inhibition protects from the polyalanine muscular dystrophy protein PABPN1.

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3283630

retrieved

28 November 2018

Stochastic and genetic factors influence tissue-specific decline in ageing C. elegans

1 reference

stated in

Crossref

reference URL

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0031321

retrieved

21 January 2018

Identifiers

DOI

10.1371/JOURNAL.PONE.0031321

1 reference

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

144372

ADS bibcode

2012PLoSO...731321V

0 references

OpenCitations bibliographic resource ID

144372

1 reference

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

144372

PMC publication ID

3283630

1 reference

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

144372

PubMed publication ID

22363618

1 reference

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

144372

ResearchGate publication ID

221859900

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