Epigenetic silencing of Notch signaling in gastrointestinal cancers (Q27022485)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23085543%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

title

Epigenetic silencing of Notch signaling in gastrointestinal cancers (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23085543%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23085543%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23085543%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

Franco Bazzoli

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23085543%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

language of work or name

1 reference

19 October 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23085543%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23085543%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23085543%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23085543%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

page(s)

4323-4327

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23085543%20AND%20SRC:MED&resulttype=core&format=json

Jagged1-mediated Notch activation induces epithelial-to-mesenchymal transition through Slug-induced repression of E-cadherin

15 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552914

E-cadherin gene mutations provide clues to diffuse type gastric carcinomas

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552914

TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552914

HES and HERP families: multiple effectors of the Notch signaling pathway

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552914

Dll1- and dll4-mediated notch signaling are required for homeostasis of intestinal stem cells

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552914

Control of endodermal endocrine development by Hes-1

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552914

Notch and Wnt signals cooperatively control cell proliferation and tumorigenesis in the intestine

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552914

Sox9 regulates cell proliferation and is required for Paneth cell differentiation in the intestinal epithelium

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552914

SOX9 is required for the differentiation of paneth cells in the intestinal epithelium

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552914

The canonical Notch signaling pathway: unfolding the activation mechanism

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552914

Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552914

Notch1 counteracts WNT/β-catenin signaling through chromatin modification in colorectal cancer

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552914

Epigenetic regulation of Delta-Like1 controls Notch1 activation in gastric cancer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552914

Fine-tuning of the intracellular canonical Notch signaling pathway.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552914

Notch signaling modulates proliferation and differentiation of intestinal crypt base columnar stem cells.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552914

Oncogenic and tumor suppressor functions of Notch in cancer: it's NOTCH what you think.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552914

Notch signalling in solid tumours: a little bit of everything but not all the time

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552914

Genetic evidence that intestinal Notch functions vary regionally and operate through a common mechanism of Math1 repression

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552914

Complex interplay between β-catenin signalling and Notch effectors in intestinal tumorigenesis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552914

Mouse atonal homolog 1 directs intestinal progenitors to secretory cell rather than absorptive cell fate

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552914

Atonal homolog 1 is required for growth and differentiation effects of notch/gamma-secretase inhibitors on normal and cancerous intestinal epithelial cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552914

Loss of enteroendocrine cells in mice alters lipid absorption and glucose homeostasis and impairs postnatal survival

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552914

Cross-talk between miRNA and Notch signaling pathways in tumor development and progression

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552914

SAM pointed domain ETS factor (SPDEF) regulates terminal differentiation and maturation of intestinal goblet cells.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552914

Proteasomal degradation of Atoh1 by aberrant Wnt signaling maintains the undifferentiated state of colon cancer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552914

Notch and cancer: a double-edged sword

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552914

Intestine-specific ablation of mouse atonal homolog 1 (Math1) reveals a role in cellular homeostasis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552914

Reciprocal targeting of Hath1 and beta-catenin by Wnt glycogen synthase kinase 3beta in human colon cancer.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552914

Aberrant activation of notch signaling in human breast cancer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552914

Signaling pathways in intestinal development and cancer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552914

Hereditary diffuse gastric cancer: predominance of multiple foci of signet ring cell carcinoma in distal stomach and transitional zone

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552914

Glycosylation regulates Notch signalling.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552914

Neurogenin3 is differentially required for endocrine cell fate specification in the intestinal and gastric epithelium

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552914

The zinc-finger transcription factor Klf4 is required for terminal differentiation of goblet cells in the colon.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552914

Protein degradation: four E3s for the notch pathway

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552914

Requirement of Math1 for secretory cell lineage commitment in the mouse intestine

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552914

Ligand-induced cleavage and regulation of nuclear entry of Notch in Drosophila melanogaster embryos

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552914

E-cadherin germline mutations in familial gastric cancer.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552914

Molecular cloning of Notch, a locus affecting neurogenesis in Drosophila melanogaster

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552914

Intestinal stem cells lacking the Math1 tumour suppressor are refractory to Notch inhibitors.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552914

Cell Lineage metastability in Gfi1-deficient mouse intestinal epithelium

31 May 2018

1 reference

Crossref

https://api.crossref.org/works/10.4161%2FCC.22388

Epigenetic control of the E-cadherin gene (CDH1) by CpG methylation in colectomy samples of patients with ulcerative colitis

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.4161%2FCC.22388

Methylation of the CDH1 promoter as the second genetic hit in hereditary diffuse gastric cancer

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.4161%2FCC.22388

Ordinary colorectal adenocarcinoma vs. primary colorectal signet-ring cell carcinoma: study matched for age, gender, grade, and stage

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23085543

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

E-cadherin gene (CDH1) promoter methylation as the second hit in sporadic diffuse gastric carcinoma

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23085543

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

E-cadherin impairment increases cell survival through Notch-dependent upregulation of Bcl-2

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23085543

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.4161/CC.22388

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23085543%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23085543%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

PubMed publication ID

23085543

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23085543%20AND%20SRC:MED&resulttype=core&format=json