Diabetic cardiomyopathy: bench to bedside (Q26997062)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22999244%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

title

Diabetic cardiomyopathy: bench to bedside (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22999244%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1 reference

diabetic cardiomyopathy

1 reference

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22999244%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Joel D Schilling

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22999244%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

language of work or name

1 reference

9 August 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22999244%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

published in

Heart failure clinics

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22999244%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22999244%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22999244%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

page(s)

619-631

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22999244%20AND%20SRC:MED&resulttype=core&format=json

Fibrosis in diabetes complications: pathogenic mechanisms and circulating and urinary markers

13 February 2020

cites work

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Inflammation and metabolic disorders

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The transcriptional coactivators, PGC-1α and β, cooperate to maintain cardiac mitochondrial function during the early stages of insulin resistance

28 September 2017

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Role of differential signaling pathways and oxidative stress in diabetic cardiomyopathy

28 September 2017

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Insulin and the heart

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Lipotoxicity in type 2 diabetic cardiomyopathy

28 September 2017

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Myocardial oxygen consumption change predicts left ventricular relaxation improvement in obese humans after weight loss

28 September 2017

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New insights into insulin resistance in the diabetic heart

28 September 2017

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RAGE biology, atherosclerosis and diabetes

28 September 2017

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The adverse impact of diabetes mellitus on left ventricular remodeling and function in patients with severe aortic stenosis

28 September 2017

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Chronic Inhibition of Pyruvate Dehydrogenase in Heart Triggers an Adaptive Metabolic Response

28 September 2017

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Peroxisome Proliferator Activated Receptor-Alpha (PPARα) and PPAR Gamma Coactivator-1alpha (PGC-1α) Regulation of Cardiac Metabolism in Diabetes

28 September 2017

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Metformin use and mortality in ambulatory patients with diabetes and heart failure

28 September 2017

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Thiazolidinediones and Cardiovascular Risk — A Question of Balance

28 September 2017

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Comparison of patients with heart failure and preserved left ventricular ejection fraction among those with versus without diabetes mellitus

28 September 2017

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Myocardial fatty acid metabolism in health and disease

28 September 2017

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Substrate-specific derangements in mitochondrial metabolism and redox balance in the atrium of the type 2 diabetic human heart

28 September 2017

1 reference

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Clinical impact of left ventricular hypertrophy and implications for regression

28 September 2017

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Chronic glucagon-like peptide-1 infusion sustains left ventricular systolic function and prolongs survival in the spontaneously hypertensive, heart failure-prone rat.

28 September 2017

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Rodent models of diabetic cardiomyopathy.

28 September 2017

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Relation of severe coronary artery narrowing to insulin or thiazolidinedione use in patients with type 2 diabetes mellitus (from the Bypass Angioplasty Revascularization Investigation 2 Diabetes Study).

28 September 2017

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Diabetes, oxidative stress, nitric oxide and mitochondria function.

28 September 2017

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Superoxide production by NAD(P)H oxidase and mitochondria is increased in genetically obese and hyperglycemic rat heart and aorta before the development of cardiac dysfunction. The role of glucose-6-phosphate dehydrogenase-derived NADPH.

28 September 2017

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Mechanisms for increased myocardial fatty acid utilization following short-term high-fat feeding

28 September 2017

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Myocardial steatosis is an independent predictor of diastolic dysfunction in type 2 diabetes mellitus

28 September 2017

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Interplay between impaired calcium regulation and insulin signaling abnormalities in diabetic cardiomyopathy

28 September 2017

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Diabetic cardiomyopathy: insights into pathogenesis, diagnostic challenges, and therapeutic options

28 September 2017

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Aminoguanidine prevents the impairment of cardiac pumping mechanics in rats with streptozotocin and nicotinamide-induced type 2 diabetes

28 September 2017

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Reduced MMP-2 activity contributes to cardiac fibrosis in experimental diabetic cardiomyopathy.

28 September 2017

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Dyslipidaemia in type II diabetic mice does not aggravate contractile impairment but increases ventricular stiffness.

28 September 2017

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Diastolic dysfunction and abnormalities of the microcirculation in type 2 diabetes

28 September 2017

1 reference

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Effect of streptozotocin-induced diabetes on left ventricular function in adult rats: an in vivo Pinhole Gated SPECT study

28 September 2017

1 reference

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Tumor necrosis factor-alpha antagonism protects from myocardial inflammation and fibrosis in experimental diabetic cardiomyopathy

28 September 2017

1 reference

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Metformin, heart failure, and lactic acidosis: is metformin absolutely contraindicated?

28 September 2017

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Pioglitazone use and heart failure in patients with type 2 diabetes and preexisting cardiovascular disease: data from the PROactive study (PROactive 08).

28 September 2017

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Recipes for creating animal models of diabetic cardiovascular disease

28 September 2017

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Lipids in the heart: a source of fuel and a source of toxins

28 September 2017

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Regulators of G protein signalling: a spotlight on emerging functions in the cardiovascular system

28 September 2017

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Insulin-resistant heart exhibits a mitochondrial biogenic response driven by the peroxisome proliferator-activated receptor-alpha/PGC-1alpha gene regulatory pathway.

28 September 2017

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Diabetes and heart failure in the post-myocardial infarction patient

28 September 2017

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Diabetes in heart failure: prevalence and impact on outcome in the population

28 September 2017

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Role of changes in cardiac metabolism in development of diabetic cardiomyopathy

28 September 2017

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Cardiac myocyte apoptosis is associated with increased DNA damage and decreased survival in murine models of obesity

28 September 2017

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Reduced mitochondrial oxidative capacity and increased mitochondrial uncoupling impair myocardial energetics in obesity

28 September 2017

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28 September 2017

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Oxidative stress and stress signaling: menace of diabetic cardiomyopathy

28 September 2017

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Mitochondrial energy metabolism in heart failure: a question of balance

28 September 2017

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Cell death and diabetic cardiomyopathy

28 September 2017

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Disruption of leptin signaling contributes to cardiac hypertrophy independently of body weight in mice

28 September 2017

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Lipotoxicity: when tissues overeat

28 September 2017

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Lipoprotein lipase (LpL) on the surface of cardiomyocytes increases lipid uptake and produces a cardiomyopathy

28 September 2017

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A critical role for PPARalpha-mediated lipotoxicity in the pathogenesis of diabetic cardiomyopathy: modulation by dietary fat content.

28 September 2017

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A novel mouse model of lipotoxic cardiomyopathy

28 September 2017

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PPAR signaling in the control of cardiac energy metabolism

28 September 2017

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Advanced glycation end-products: a review

28 September 2017

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Left ventricular hypertrophy in hypertension: stimuli, patterns, and consequences

28 September 2017

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Mechanisms determining course and outcome of diabetic patients who have had acute myocardial infarction

28 September 2017

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Collagen remodelling in myocardia of patients with diabetes

28 September 2017

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New type of cardiomyopathy associated with diabetic glomerulosclerosis

28 September 2017

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Evidence for cardiomyopathy in familial diabetes mellitus

28 September 2017

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Type 1 diabetic cardiomyopathy in the Akita (Ins2WT/C96Y) mouse model is characterized by lipotoxicity and diastolic dysfunction with preserved systolic function

28 September 2017

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Nutrient stress activates inflammation and reduces glucose metabolism by suppressing AMP-activated protein kinase in the heart

31 May 2018

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Thiazolidinediones, metformin, and outcomes in older patients with diabetes and heart failure: an observational study

31 May 2018

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Catalase protects cardiomyocyte function in models of type 1 and type 2 diabetes

31 May 2018

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The epidemiology of cardiovascular disease in type 2 diabetes mellitus: how sweet it is … or is it?

31 May 2018

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Prevalence and mortality of acute myocardial infarction in patients with diabetes.

31 May 2018

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Determinants of Hospital Admission and Case Fatality in Diabetic Patients With Myocardial Infarction

31 May 2018

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Increased mortality of diabetics after acute myocardial infarction attributed to diffusely impaired left ventricular performance as assessed by echocardiography

31 May 2018

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Diabetes and cardiovascular disease. The Framingham study

31 May 2018

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Long-term severe diabetes only leads to mild cardiac diastolic dysfunction in Zucker diabetic fatty rats

31 May 2018

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A dipeptidyl peptidase-4 inhibitor, des-fluoro-sitagliptin, improves endothelial function and reduces atherosclerotic lesion formation in apolipoprotein E-deficient mice

28 November 2018

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Metformin therapy and prognosis of patients with heart failure and new-onset diabetes mellitus. A propensity-matched study in the community

28 November 2018

1 reference

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PKCβ inhibition with ruboxistaurin reduces oxidative stress and attenuates left ventricular hypertrophy and dysfunction in rats with streptozotocin-induced diabetes.

28 November 2018

1 reference

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Cardiac remodeling rather than disturbed myocardial energy metabolism is associated with cardiac dysfunction in diabetic rats

28 November 2018

1 reference

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Diabetes mellitus worsens diastolic left ventricular dysfunction in aortic stenosis through altered myocardial structure and cardiomyocyte stiffness.

28 November 2018

1 reference

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Obesity promotes left ventricular concentric rather than eccentric geometric remodeling and hypertrophy independent of blood pressure.

28 November 2018

1 reference

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The roles of MMP-2/TIMP-2 in extracellular matrix remodelling in the hearts of STZ-induced diabetic rats

28 November 2018

1 reference

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Mitochondrial energetics in the heart in obesity-related diabetes: direct evidence for increased uncoupled respiration and activation of uncoupling proteins.

28 November 2018

1 reference

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Cardioprotective and anti-inflammatory effects of interleukin converting enzyme inhibition in experimental diabetic cardiomyopathy.

28 November 2018

1 reference

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Protection of cardiac mitochondria by overexpression of MnSOD reduces diabetic cardiomyopathy

28 November 2018

1 reference

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Mechanisms of [Ca2+]i transient decrease in cardiomyopathy of db/db type 2 diabetic mice

28 November 2018

1 reference

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Increased myocardial fatty acid metabolism in patients with type 1 diabetes mellitus

28 November 2018

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Myocardial infarction and heart failure in the db/db diabetic mouse

28 November 2018

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Screening for heart disease in diabetic subjects

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457018

Insulin-treated diabetes is associated with a marked increase in mortality in patients with advanced heart failure

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457018

Transgenic expression of fatty acid transport protein 1 in the heart causes lipotoxic cardiomyopathy

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457018

Glucagon-like peptide 1 can directly protect the heart against ischemia/reperfusion injury

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457018

Intramyocardial lipid accumulation in the failing human heart resembles the lipotoxic rat heart

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457018

The incidence of congestive heart failure associated with antidiabetic therapies

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457018

Streptozotocin directly impairs cardiac contractile function in isolated ventricular myocytes via a p38 map kinase-dependent oxidative stress mechanism

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457018

Effect of obesity and insulin resistance on myocardial substrate metabolism and efficiency in young women

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457018

Effects of glucagon-like peptide-1 in patients with acute myocardial infarction and left ventricular dysfunction after successful reperfusion

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457018

Activities of xanthine oxidoreductase and antioxidant enzymes in different tissues of diabetic rats

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457018

Streptozotocin-induced hyperglycemia exacerbates left ventricular remodeling and failure after experimental myocardial infarction

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457018

Metallothionein prevents diabetes-induced deficits in cardiomyocytes by inhibiting reactive oxygen species production

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457018

Age-dependent changes in metabolism, contractile function, and ischemic sensitivity in hearts from db/db mice

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457018

Defective intracellular Ca(2+) signaling contributes to cardiomyopathy in Type 1 diabetic rats

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457018

Adaptive increase in pyruvate dehydrogenase kinase 4 during starvation is mediated by peroxisome proliferator-activated receptor alpha.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457018

Impact of diabetes on cardiac structure and function: the strong heart study

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457018

Cardiovascular abnormalities in transgenic mice with reduced brown fat: an animal model of human obesity.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457018

Clinical course of myocardial infarction among diabetic patients

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457018

Overexpression of glutathione peroxidase attenuates myocardial remodeling and preserves diastolic function in diabetic heart

28 November 2018

1 reference

12 December 2020

Myocardial cell death in human diabetes

1 reference

12 December 2020

Changes in cardiac protein kinase C activities and isozymes in streptozotocin-induced diabetes

1 reference

12 December 2020

Type 2 diabetes is associated with left ventricular concentric remodeling in hypertensive patients

1 reference

12 December 2020

Expression of connective tissue growth factor is increased in injured myocardium associated with protein kinase C beta2 activation and diabetes

1 reference

12 December 2020

Acute myocardial infarction in diabetes mellitus and significance of congestive heart failure as a prognostic factor

1 reference

12 December 2020

Prevalence, clinical characteristics and outcome in patients with chronic heart failure and diabetes

1 reference

12 December 2020

Effects of diet-induced obesity on inflammation and remodeling after myocardial infarction

1 reference

12 December 2020

Diabetes increases apoptosis and necrosis in both ischemic and nonischemic human myocardium: role of caspases and poly-adenosine diphosphate-ribose polymerase

1 reference

12 December 2020

Cardiac steatosis in diabetes mellitus: a 1H-magnetic resonance spectroscopy study

1 reference

12 December 2020

Flow mediated dilatation and cardiac function in type 1 diabetes mellitus

1 reference

12 December 2020

10.1016/J.HFC.2012.06.007

Identifiers

DOI

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22999244%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22999244%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

PubMed publication ID

22999244

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22999244%20AND%20SRC:MED&resulttype=core&format=json