Interplay between impaired calcium regulation and insulin signaling abnormalities in diabetic cardiomyopathy (Q37278004)

19 August 2017

1 reference

title

Interplay between impaired calcium regulation and insulin signaling abnormalities in diabetic cardiomyopathy (English)

1 reference

19 August 2017

1 reference

Djamel Lebeche

1 reference

19 August 2017

Amy J Davidoff

series ordinal

1 reference

19 August 2017

Roger J Hajjar

series ordinal

1 reference

19 August 2017

publication date

23 September 2008

1 reference

Nature Clinical Practice Cardiovascular Medicine

19 August 2017

published in

1 reference

19 August 2017

1 reference

19 August 2017

1 reference

19 August 2017

page(s)

715-724

1 reference

Diabetes, hypertension, and cardiovascular disease: an update

19 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

Restoration of contractile function in isolated cardiomyocytes from failing human hearts by gene transfer of SERCA2a

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

Role of PKC in autocrine regulation of rat ventricular K+ currents by angiotensin and endothelin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

Insulin signaling coordinately regulates cardiac size, metabolism, and contractile protein isoform expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

Diabetic cardiomyopathy revisited

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

7 January 2021

Increasing cardiovascular disease burden due to diabetes mellitus: the Framingham Heart Study

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

7 January 2021

New type of cardiomyopathy associated with diabetic glomerulosclerosis

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

7 January 2021

Echocardiographic evidence for the existence of a distinct diabetic cardiomyopathy (The Framingham Heart Study)

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

7 January 2021

Diabetic cardiomyopathy: recent evidence from mouse models of type 1 and type 2 diabetes

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

7 January 2021

Diabetic cardiomyopathy: the search for a unifying hypothesis

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

7 January 2021

Insulin-resistant cardiomyopathy clinical evidence, mechanisms, and treatment options

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

7 January 2021

Role of changes in cardiac metabolism in development of diabetic cardiomyopathy

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

7 January 2021

Diabetes mellitus induces changes in cardiac myosin of the rat

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

7 January 2021

Troponin subunits contribute to altered myosin ATPase activity in diabetic cardiomyopathy

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

7 January 2021

Restoration of diabetes-induced abnormal local Ca2+ release in cardiomyocytes by angiotensin II receptor blockade.

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

7 January 2021

Alterations in contractile properties and Ca2+ handling in streptozotocin-induced diabetic rat myocardium

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

7 January 2021

Calcium and potassium currents in ventricular myocytes isolated from diabetic rats

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

7 January 2021

Depressed cardiac sarcoplasmic reticular function from diabetic rats

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

7 January 2021

Decrease in sodium-calcium exchange and calcium currents in diabetic rat ventricular myocytes

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

7 January 2021

Effects of diabetes on ryanodine receptor Ca release channel (RyR2) and Ca2+ homeostasis in rat heart.

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

7 January 2021

Altered SR protein expression associated with contractile dysfunction in diabetic rat hearts

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

7 January 2021

Short-term diabetes alters K+ currents in rat ventricular myocytes

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

7 January 2021

Decreased L-type Ca2+ current in cardiac myocytes of type 1 diabetic Akita mice due to reduced phosphatidylinositol 3-kinase signaling

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

7 January 2021

Impaired SERCA function contributes to cardiomyocyte dysfunction in insulin resistant rats

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

7 January 2021

Decreased sarcoplasmic reticulum activity and contractility in diabetic db/db mouse heart

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

7 January 2021

Overexpression of the sarcoplasmic reticulum Ca(2+)-ATPase improves myocardial contractility in diabetic cardiomyopathy

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

7 January 2021

Diminished function and expression of the cardiac Na+-Ca2+ exchanger in diabetic rats: implication in Ca2+ overload

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

7 January 2021

Mechanisms of [Ca2+]i transient decrease in cardiomyopathy of db/db type 2 diabetic mice

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

7 January 2021

Mechanisms underlying depressed Na+/Ca2+ exchanger activity in the diabetic heart

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

7 January 2021

Effects of Na(+)/Ca(2+)-exchanger overexpression on excitation-contraction coupling in adult rabbit ventricular myocytes.

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

7 January 2021

Depressed PKA activity contributes to impaired SERCA function and is linked to the pathogenesis of glucose-induced cardiomyopathy

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

7 January 2021

Ryanodine receptors/calcium release channels in heart failure and sudden cardiac death

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

7 January 2021

Mitochondrial uncoupling: a key contributor to reduced cardiac efficiency in diabetes.

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

7 January 2021

Defective mitochondrial biogenesis: a hallmark of the high cardiovascular risk in the metabolic syndrome?

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

7 January 2021

Mitochondria: the hub of cellular Ca2+ signaling

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

7 January 2021

Regulation of contractile proteins in diabetic heart

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

7 January 2021

Depressed cardiac myofilament function in human diabetes mellitus

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

7 January 2021

Diminished Ca2+ sensitivity of skinned cardiac muscle contractility coincident with troponin T-band shifts in the diabetic rat

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

7 January 2021

Collagen cross-link breakers: a beginning of a new era in the treatment of cardiovascular changes associated with aging, diabetes, and hypertension

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

7 January 2021

Diabetes increases formation of advanced glycation end products on Sarco(endo)plasmic reticulum Ca2+-ATPase

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

7 January 2021

Chronic diabetes increases advanced glycation end products on cardiac ryanodine receptors/calcium-release channels

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

7 January 2021

Role of protein O-linked N-acetyl-glucosamine in mediating cell function and survival in the cardiovascular system

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

7 January 2021

Reversibility of diabetic cardiomyopathy with insulin in rats

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

7 January 2021

Myocardial insulin resistance and cardiac complications of diabetes.

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

7 January 2021

Convergence of glucose- and fatty acid-induced abnormal myocardial excitation-contraction coupling and insulin signalling

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

7 January 2021

Myocardial insulin action and the contribution of insulin resistance to the pathogenesis of diabetic cardiomyopathy.

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

7 January 2021

Insulin resistance and cardiovascular risk: New insights from molecular and cellular biology

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

7 January 2021

Contractile dysfunction in hypertrophied hearts with deficient insulin receptor signaling: possible role of reduced capillary density.

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

7 January 2021

Characterization of signal transduction and glucose transport in skeletal muscle from type 2 diabetic patients

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

7 January 2021

Molecular analysis of insulin resistance in isolated ventricular cardiomyocytes of obese Zucker rats

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

7 January 2021

Etiology of insulin resistance

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

7 January 2021

A conserved role for phosphatidylinositol 3-kinase but not Akt signaling in mitochondrial adaptations that accompany physiological cardiac hypertrophy.

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

7 January 2021

Cycling of O-linked beta-N-acetylglucosamine on nucleocytoplasmic proteins

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

7 January 2021

Mechanical and metabolic rescue in a type II diabetes model of cardiomyopathy by targeted gene transfer

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

7 January 2021

Insulin Receptor Substrate Proteins Create a Link between the Tyrosine Phosphorylation Cascade and the Ca2+-ATPases in Muscle and Heart

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

7 January 2021

Cardiac dysfunction induced by high-fat diet is associated with altered myocardial insulin signalling in rats

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

7 January 2021

Diabetic cardiomyocyte dysfunction and myocyte insulin resistance: role of glucose-induced PKC activity

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

7 January 2021

Insulin improves cardiomyocyte contractile function through enhancement of SERCA2a activity in simulated ischemia/reperfusion

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

7 January 2021

Glycogen synthase kinase-3beta regulates growth, calcium homeostasis, and diastolic function in the heart

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

7 January 2021

Insulin causes [Ca2+]i-dependent and [Ca2+]i-independent positive inotropic effects in failing human myocardium

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

7 January 2021

Phosphatidylinositol 3-kinase functionally compartmentalizes the concurrent G(s) signaling during beta2-adrenergic stimulation

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

7 January 2021

Akt induces enhanced myocardial contractility and cell size in vivo in transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

7 January 2021

Regulation of myocardial contractility and cell size by distinct PI3K-PTEN signaling pathways

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

7 January 2021

Cardiac sarcoplasmic reticulum calcium release and load are enhanced by subcellular cAMP elevations in PI3Kgamma-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

7 January 2021

Nuclear targeting of Akt enhances ventricular function and myocyte contractility

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

7 January 2021

Mechanism of enhanced cardiac function in mice with hypertrophy induced by overexpressed Akt.

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

7 January 2021

Insulin-Like Growth Factor-1 and PTEN Deletion Enhance Cardiac L-Type Ca 2+ Currents via Increased PI3Kα/PKB Signaling

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

7 January 2021

Insulin resistance in patients with cardiac hypertrophy

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1347

7 January 2021

Identifiers

DOI

10.1038/NCPCARDIO1347

1 reference

19 August 2017

1 reference