Perforin pores in the endosomal membrane trigger the release of endocytosed granzyme B into the cytosol of target cells (Q24630734)

22 June 2017

title

Perforin pores in the endosomal membrane trigger the release of endocytosed granzyme B into the cytosol of target cells (English)

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identical protein binding

22 June 2017

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GOA release 2020-03-11

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GOA release 2020-03-11

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Steeve Boulant

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Tomas Kirchhausen

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22 June 2017

Judy Lieberman

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22 June 2017

Jerome Thiery

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22 June 2017

Dennis Keefe

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22 June 2017

Emmanuel Boucrot

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22 June 2017

Michael Walch

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22 June 2017

Denis Martinvalet

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22 June 2017

Ing Swie Goping

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22 June 2017

R Chris Bleackley

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22 June 2017

language of work or name

English

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publication date

19 June 2011

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22 June 2017

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22 June 2017

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22 June 2017

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22 June 2017

page(s)

770-777

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Human perforin employs different avenues to damage membranes

22 June 2017

cites work

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7 April 2017

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Structural/functional similarity between proteins involved in complement- and cytotoxic T-lymphocyte-mediated cytolysis

7 April 2017

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Perforin activates clathrin- and dynamin-dependent endocytosis, which is required for plasma membrane repair and delivery of granzyme B for granzyme-mediated apoptosis

7 April 2017

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7 April 2017

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7 April 2017

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7 April 2017

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7 April 2017

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7 April 2017

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Granzyme A activates another way to die

27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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Emission of membrane vesicles: roles in complement resistance, immunity and cancer

27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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Cytosolic delivery of granzyme B by bacterial toxins: evidence that endosomal disruption, in addition to transmembrane pore formation, is an important function of perforin

27 September 2017

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Microtubules are involved in bafilomycin A1-induced tubulation and Rab5-dependent vacuolation of early endosomes

27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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The isolation and characterization of a family of serine protease genes expressed in activated cytotoxic T lymphocytes

27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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The immunological synapse of CTL contains a secretory domain and membrane bridges.

30 May 2018

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Perforin triggers a plasma membrane-repair response that facilitates CTL induction of apoptosis

21 January 2018

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21 January 2018

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Assembly of two types of tubules with putative cytolytic function by cloned natural killer cells

28 November 2018

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New Paradigm for Lymphocyte Granule-mediated Cytotoxicity

21 January 2018

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Human perforin permeabilizing activity, but not binding to lipid membranes, is affected by pH

21 January 2018

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12 December 2020

A novel serine esterase expressed by cytotoxic T lymphocytes

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12 December 2020

Cytolytic T-cell granules: biochemical properties and functional specificity

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12 December 2020

Inhibition of the lytic activity of perforin (cytolysin) and of late complement components by proteoglycans

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12 December 2020

Bafilomycin A1, a specific inhibitor of vacuolar-type H(+)-ATPase, inhibits acidification and protein degradation in lysosomes of cultured cells

1 reference

12 December 2020

Characterization of Rab5:Q79L-stimulated endosome fusion

1 reference

12 December 2020

New paradigm for lymphocyte granule-mediated cytotoxicity. Target cells bind and internalize granzyme B, but an endosomolytic agent is necessary for cytosolic delivery and subsequent apoptosis

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12 December 2020

V-ATPase: a potential pH sensor

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12 December 2020

Identifiers

DOI

10.1038/NI.2050

1 reference

OpenCitations bibliographic resource ID

22 June 2017

2212661

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2212661

1 reference