Lactose permease and the alternating access mechanism (Q24630374)

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English	Lactose permease and the alternating access mechanism	scientific article

Statements

instance of

scholarly article

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title

Lactose permease and the alternating access mechanism (English)

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author

Howard Ronald Kaback

series ordinal

3

object named as

H Ronald Kaback

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author name string

Irina Smirnova

series ordinal

1

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Vladimir Kasho

series ordinal

2

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language of work or name

English

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publication date

15 November 2011

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published in

Biochemistry

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volume

50

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issue

45

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page(s)

9684-93

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cites work

Crystal structure of lactose permease in complex with an affinity inactivator yields unique insight into sugar recognition

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PubMed Central

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7 April 2017

Crystal structure of a prokaryotic homologue of the mammalian oligopeptide-proton symporters, PepT1 and PepT2

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7 April 2017

Structure of a fucose transporter in an outward-open conformation

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7 April 2017

Structural determination of wild-type lactose permease

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PubMed Central

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7 April 2017

Structure and mechanism of the glycerol-3-phosphate transporter from Escherichia coli

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PubMed Central

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7 April 2017

Structure and mechanism of the lactose permease of Escherichia coli

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PubMed Central

reference URL

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7 April 2017

Structure of the multidrug transporter EmrD from Escherichia coli

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PubMed Central

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7 April 2017

The kamikaze approach to membrane transport

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PubMed Central

reference URL

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7 April 2017

Opening the periplasmic cavity in lactose permease is the limiting step for sugar binding

1 reference

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PubMed Central

reference URL

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27 September 2017

Cytoplasmic permeation pathway of neurotransmitter transporters

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PubMed Central

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27 September 2017

An early event in the transport mechanism of LacY protein: interaction between helices V and I.

1 reference

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PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210931

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27 September 2017

Probing the Periplasmic-Open State of Lactose Permease in Response to Sugar Binding and Proton Translocation

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PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210931

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27 September 2017

Sugar binding induces the same global conformational change in purified LacY as in the native bacterial membrane

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PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210931

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27 September 2017

Helix dynamics in LacY: helices II and IV

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PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210931

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27 September 2017

Probing of the rates of alternating access in LacY with Trp fluorescence

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210931

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27 September 2017

Residues gating the periplasmic pathway of LacY.

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210931

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27 September 2017

Residues in the H+ translocation site define the pKa for sugar binding to LacY.

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210931

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27 September 2017

Electrophysiological characterization of LacY.

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210931

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27 September 2017

Protonation and sugar binding to LacY.

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210931

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27 September 2017

Opening and closing of the periplasmic gate in lactose permease

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210931

retrieved

27 September 2017

Sugar binding induces an outward facing conformation of LacY.

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210931

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27 September 2017

Single-molecule FRET reveals sugar-induced conformational dynamics in LacY.

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210931

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27 September 2017

Membrane protein insertion: the biology-physics nexus

1 reference

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PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210931

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27 September 2017

Sugar transport across lactose permease probed by steered molecular dynamics

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210931

retrieved

27 September 2017

Site-directed alkylation and the alternating access model for LacY.

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210931

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27 September 2017

Energetics of ligand-induced conformational flexibility in the lactose permease of Escherichia coli

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210931

retrieved

27 September 2017

Sugar binding and protein conformational changes in lactose permease

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210931

retrieved

27 September 2017

Lessons from lactose permease

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210931

retrieved

27 September 2017

Structural evidence for induced fit and a mechanism for sugar/H+ symport in LacY.

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210931

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27 September 2017

Principles of selective ion transport in channels and pumps

1 reference

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PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210931

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27 September 2017

Structure and mechanism of the lactose permease

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210931

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27 September 2017

Interhelical packing modulates conformational flexibility in the lactose permease of Escherichia coli

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210931

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27 September 2017

A mutation in the lactose permease of Escherichia coli that decreases conformational flexibility and increases protein stability

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210931

retrieved

27 September 2017

Distance measurements in the nanometer range by pulse EPR.

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210931

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27 September 2017

An approach to membrane protein structure without crystals.

1 reference

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PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210931

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27 September 2017

Families of transmembrane sugar transport proteins

1 reference

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PubMed Central

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27 September 2017

Helix packing in polytopic membrane proteins: role of glycine in transmembrane helix association

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PubMed Central

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27 September 2017

The preference of tryptophan for membrane interfaces.

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PubMed Central

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27 September 2017

Cys-scanning mutagenesis: a novel approach to structure function relationships in polytopic membrane proteins

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PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210931

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27 September 2017

The substrate-binding site in the lactose permease of Escherichia coli

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PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210931

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27 September 2017

Fourier transform infrared spectroscopy reveals a rigid alpha-helical assembly for the tetrameric Streptomyces lividans K+ channel

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PubMed Central

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27 September 2017

Exchange, efflux, and substrate binding by cysteine mutants of the lactose permease of Escherichia coli

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PubMed Central

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27 September 2017

Determination of helix-helix interactions in membranes by rotational resonance NMR

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PubMed Central

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27 September 2017

Purified reconstituted lac carrier protein from Escherichia coli is fully functional

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PubMed Central

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27 September 2017

Sequence specificity in the dimerization of transmembrane alpha-helices

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27 September 2017

Site-directed alkylation studies with LacY provide evidence for the alternating access model of transport

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PubMed Central

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30 May 2018

Clogging the periplasmic pathway in LacY.

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PubMed Central

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30 May 2018

The Cys154-->Gly mutation in LacY causes constitutive opening of the hydrophilic periplasmic pathway

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PubMed Central

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30 May 2018

Site-directed alkylation of LacY: effect of the proton electrochemical gradient

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PubMed Central

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30 May 2018

Direct sugar binding to LacY measured by resonance energy transfer

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PubMed Central

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30 May 2018

Site-directed sulfhydryl labeling of the lactose permease of Escherichia coli: N-ethylmaleimide-sensitive face of helix II.

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PubMed Central

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30 May 2018

Site-directed sulfhydryl labeling of the lactose permease of Escherichia coli: helix VII.

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PubMed Central

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30 May 2018

Toward understanding tryptophan fluorescence in proteins

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30 May 2018

Lactose transport coupled to proton movements in Escherichia coli

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30 May 2018

Stoicheiometry of lactose–proton symport across the plasma membrane of Escherichia coli

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30 May 2018

Role of transmembrane domain interactions in the assembly of class II MHC molecules

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30 May 2018

Characterization of purified, reconstituted site-directed cysteine mutants of the lactose permease of Escherichia coli.

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PubMed Central

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30 May 2018

Purification, reconstitution, and characterization of the lac permease of Escherichia coli.

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19 June 2018

cys154 Is important for lac permease activity in Escherichia coli.

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19 June 2018

The alternating-access mechanism of MFS transporters arises from inverted-topology repeats.

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28 November 2018

Structural characterization of the osmosensor ProP.

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28 November 2018

Cysteine-scanning mutagenesis of helix VI and the flanking hydrophilic domains on the lactose permease of Escherichia coli

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28 November 2018

Dead-Time Free Measurement of Dipole–Dipole Interactions between Electron Spins

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Monoclonal antibodies against the lac carrier protein from Escherichia coli. 2. Binding studies with membrane vesicles and proteoliposomes reconstituted with purified lac carrier protein

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Histidine-aromatic interactions in barnase. Elevation of histidine pKa and contribution to protein stability

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Substituted-cysteine accessibility method

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Fourier transform infrared analysis of purified lactose permease: a monodisperse lactose permease preparation is stably folded, alpha-helical, and highly accessible to deuterium exchange

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Identifiers

DOI

10.1021/BI2014294

1 reference

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1089756

OpenCitations bibliographic resource ID

1089756

1 reference

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1089756

PMC publication ID

3210931

1 reference

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1089756

PubMed publication ID

21995338

1 reference

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1089756

ResearchGate publication ID

51717144

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