An approach to membrane protein structure without crystals. (Q30332082)

14 September 2017

An approach to membrane protein structure without crystals. (English)

1 reference

14 September 2017

1 reference

H Ronald Kaback

1 reference

14 September 2017

Paul L Sorgen

1 reference

14 September 2017

Yonglin Hu

series ordinal

1 reference

14 September 2017

Lan Guan

series ordinal

1 reference

14 September 2017

Mark E Girvin

series ordinal

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14 September 2017

language of work or name

English

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publication date

21 October 2002

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Proceedings of the National Academy of Sciences of the United States of America

14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

14037-14040

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Projection structure at 8 A resolution of the melibiose permease, an Na-sugar co-transporter from Escherichia coli

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137832

Changing the lactose permease of Escherichia coli into a galactose-specific symporter

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137832

Surface-exposed positions in the transmembrane helices of the lactose permease of Escherichia coli determined by intermolecular thiol cross-linking

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137832

Helices VII and X in the lactose permease of Escherichia coli: proximity and ligand-induced distance changes

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137832

Helix packing in the lactose permease of Escherichia coli: localization of helix VI.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137832

Site-directed sulfhydryl labeling of the lactose permease of Escherichia coli: helices IV and V that contain the major determinants for substrate binding

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137832

Projection structure and molecular architecture of OxlT, a bacterial membrane transporter.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137832

The kamikaze approach to membrane transport

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137832

Site-directed sulfhydryl labeling of the lactose permease of Escherichia coli: helix X.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137832

Site-directed sulfhydryl labeling of the lactose permease of Escherichia coli: N-ethylmaleimide-sensitive face of helix II.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137832

Site-directed sulfhydryl labeling of the lactose permease of Escherichia coli: helix VII.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137832

Thiol cross-linking of cytoplasmic loops in the lactose permease of Escherichia coli

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137832

Three-dimensional structure of the ion-coupled transport protein NhaA.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137832

Location of helix III in the lactose permease of Escherichia coli as determined by site-directed thiol cross-linking

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137832

Proximity relationships between helices I and XI or XII in the lactose permease of Escherichia coli determined by site-directed thiol cross-linking

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137832

Proximity between Glu126 and Arg144 in the lactose permease of Escherichia coli

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137832

Helix packing in the lactose permease of Escherichia coli determined by site-directed thiol cross-linking: helix I is close to helices V and XI.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137832

Tertiary contacts of helix V in the lactose permease determined by site-directed chemical cross-linking in situ

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137832

Site-directed chemical cross-linking demonstrates that helix IV is close to helices VII and XI in the lactose permease

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137832

Cys-scanning mutagenesis: a novel approach to structure function relationships in polytopic membrane proteins

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137832

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137832

Transmembrane helix tilting and ligand-induced conformational changes in the lactose permease determined by site-directed chemical crosslinking in situ

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137832

Fourier transform infrared spectroscopy reveals a rigid alpha-helical assembly for the tetrameric Streptomyces lividans K+ channel

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137832

Proximity of helices VIII (Ala273) and IX (Met299) in the lactose permease of Escherichia coli.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137832

Arginine 302 (helix IX) in the lactose permease of Escherichia coli is in close proximity to glutamate 269 (helix VIII) as well as glutamate 325.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137832

Helix proximity and ligand-induced conformational changes in the lactose permease of Escherichia coli determined by site-directed chemical crosslinking

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137832

A general method for determining helix packing in membrane proteins in situ: helices I and II are close to helix VII in the lactose permease of Escherichia coli

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137832

MOLMOL: a program for display and analysis of macromolecular structures

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137832

Purified lac permease and cytochrome o oxidase are functional as monomers.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137832

From membrane to molecule to the third amino acid from the left with a membrane transport protein

20 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.182552199

Torsion-angle molecular dynamics as a new efficient tool for NMR structure calculation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.182552199

Functional estimation of loop-helix boundaries in the lactose permease of Escherichia coli by single amino acid deletion analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.182552199

Ligand-induced changes in periplasmic loops in the lactose permease of Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.182552199

Tilting of helix I and ligand-induced changes in the lactose permease determined by site-directed chemical cross-linking in situ.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.182552199

Engineering a metal binding site within a polytopic membrane protein, the lactose permease of Escherichia coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.182552199

Use of designed metal-binding sites to study helix proximity in the lactose permease of Escherichia coli. 1. Proximity of helix VII (Asp237 and Asp240) with helices X (Lys319) and XI (Lys358).

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.182552199

Use of designed metal-binding sites to study helix proximity in the lactose permease of Escherichia coli. 2. Proximity of helix IX (Arg302) with helix X (His322 and Glu325).

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.182552199

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.182552199

The C-4 hydroxyl group of galactopyranosides is the major determinant for ligand recognition by the lactose permease of Escherichia coli

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137832

Two-dimensional crystallization of Escherichia coli lactose permease

26 November 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.182552199

A revised model for the structure and function of the lactose permease. Evidence that a face on transmembrane segment 2 is important for conformational changes

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.182552199

Fourier transform infrared analysis of purified lactose permease: a monodisperse lactose permease preparation is stably folded, alpha-helical, and highly accessible to deuterium exchange

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.182552199

Probing the conformation of the lactose permease of Escherichia coli by in situ site-directed sulfhydryl modification

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.182552199

21 January 2018

Identifiers

DOI

10.1073/PNAS.182552199

1 reference

14 September 2017

0 references

1 reference

14 September 2017

PubMed publication ID

12391320

1 reference