Two-pore channels form homo- and heterodimers (Q24337485)

Two pore segment channel 1

GOA release 2020-03-11

1 reference

identical protein binding

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Antony Giuseppe Galione

Antony Galione

0 references

Katja Rietdorf

0 references

Tim M Funnell

0 references

Margarida Ruas

0 references

Jennifer Heinemann

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John Parrington

Journal of Biological Chemistry

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language of work or name

English

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publication date

28 October 2011

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published in

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volume

286

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issue

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page(s)

37058-62

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cites work

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An NAADP-gated two-pore channel targeted to the plasma membrane uncouples triggering from amplifying Ca2+ signals

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Characterization of two-pore channel 2 (TPCN2)-mediated Ca2+ currents in isolated lysosomes

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An ancestral deuterostome family of two-pore channels mediates nicotinic acid adenine dinucleotide phosphate-dependent calcium release from acidic organelles

19 March 2017

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Transient receptor potential mucolipin 1 (TRPML1) and two-pore channels are functionally independent organellar ion channels

7 April 2017

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Membrane topology of NAADP-sensitive two-pore channels and their regulation by N-linked glycosylation.

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Heteromultimeric TRPML channel assemblies play a crucial role in the regulation of cell viability models and starvation-induced autophagy

27 September 2017

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Two-pore channels: Regulation by NAADP and customized roles in triggering calcium signals

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TPCs: Endolysosomal channels for Ca2+ mobilization from acidic organelles triggered by NAADP

27 September 2017

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27 September 2017

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The Ca(2+) channel TRPML3 regulates membrane trafficking and autophagy

27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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TRPML and lysosomal function

27 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3199452

Molecular determinants of TRP channel assembly

27 September 2017

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International Union of Pharmacology. L. Nomenclature and structure-function relationships of CatSper and two-pore channels.

27 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3199452

Homo- and heteromeric assembly of TRP channel subunits

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3199452

The epithelial calcium channels TRPV5 and TRPV6: regulation and implications for disease

27 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3199452

Ca2+-selective transient receptor potential V channel architecture and function require a specific ankyrin repeat

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3199452

Mammalian TRPC channel subunit assembly

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3199452

The three-dimensional structure of the cardiac L-type voltage-gated calcium channel: comparison with the skeletal muscle form reveals a common architectural motif

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3199452

Quantitative fluorescence resonance energy transfer measurements using fluorescence microscopy

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3199452

Inositol 1,4,5-trisphosphate receptors in endocrine cells: localization and association in hetero- and homotetramers

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3199452

Heterotetrameric complex formation of inositol 1,4,5-trisphosphate receptor subunits

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3199452

Nicotinic acid adenine dinucleotide phosphate (NAADP) regulates autophagy in cultured astrocytes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3199452

Interdomain Interactions Underlying Activation of Cyclic Nucleotide-Gated Channels

30 May 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C111.289835

Functional multimerization of mucolipin channel proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C111.289835

Dissecting intersubunit contacts in cyclic nucleotide-gated ion channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C111.289835

The role of intraorganellar Ca(2+) in late endosome-lysosome heterotypic fusion and in the reformation of lysosomes from hybrid organelles

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C111.289835

Identification of a tetramerization domain in the C terminus of the vanilloid receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C111.289835

NAADP as an intracellular messenger regulating lysosomal calcium-release channels

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21903581

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Asymmetric arrangement of auxiliary subunits of skeletal muscle voltage-gated l-type Ca(2+) channel

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21903581

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A potentially dynamic lysosomal role for the endogenous TRPML proteins

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21903581