Transient receptor potential mucolipin 1 (TRPML1) and two-pore channels are functionally independent organellar ion channels (Q35067713)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21540176%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

title

Transient receptor potential mucolipin 1 (TRPML1) and two-pore channels are functionally independent organellar ion channels (English)

1 reference

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30 January 2020

1 reference

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30 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21540176%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

Soichiro Yamaguchi

1 reference

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30 January 2020

Archana Jha

1 reference

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30 January 2020

Qin Li

1 reference

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30 January 2020

Abigail A Soyombo

1 reference

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30 January 2020

Dev Churamani

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30 January 2020

Eugen Brailoiu

1 reference

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30 January 2020

Shmuel Muallem

1 reference

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30 January 2020

language of work or name

English

0 references

publication date

3 May 2011

1 reference

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Journal of Biological Chemistry

30 January 2020

published in

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30 January 2020

volume

286

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30 January 2020

issue

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30 January 2020

page(s)

22934-22942

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describes a project that uses

30 January 2020

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3123061/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

A Role for the Ca2+ Channel TRPML1 in Gastric Acid Secretion, Based on Analysis of Knockout Mice

1 reference

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An NAADP-gated two-pore channel targeted to the plasma membrane uncouples triggering from amplifying Ca2+ signals

8 July 2018

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TPC2 is a novel NAADP-sensitive Ca2+ release channel, operating as a dual sensor of luminal pH and Ca2+

8 July 2018

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Two-pore channels: Regulation by NAADP and customized roles in triggering calcium signals

8 July 2018

1 reference

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Characterization of two-pore channel 2 (TPCN2)-mediated Ca2+ currents in isolated lysosomes

8 July 2018

1 reference

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Properties of the TRPML3 channel pore and its stable expansion by the Varitint-Waddler-causing mutation

8 July 2018

1 reference

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Purified TPC isoforms form NAADP receptors with distinct roles for Ca(2+) signaling and endolysosomal trafficking

8 July 2018

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Acidic calcium stores open for business: expanding the potential for intracellular Ca2+ signaling

8 July 2018

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Deviant nicotinic acid adenine dinucleotide phosphate (NAADP)-mediated Ca2+ signaling upon lysosome proliferation.

8 July 2018

1 reference

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Small molecule activators of TRPML3

8 July 2018

1 reference

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TPCs: Endolysosomal channels for Ca2+ mobilization from acidic organelles triggered by NAADP

8 July 2018

1 reference

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Aberrant Ca2+ handling in lysosomal storage disorders

8 July 2018

1 reference

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An ancestral deuterostome family of two-pore channels mediates nicotinic acid adenine dinucleotide phosphate-dependent calcium release from acidic organelles

8 July 2018

1 reference

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Essential requirement for two-pore channel 1 in NAADP-mediated calcium signaling

8 July 2018

1 reference

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Second messenger signaling: multiple receptors for NAADP.

8 July 2018

1 reference

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The two-pore channel TPCN2 mediates NAADP-dependent Ca(2+)-release from lysosomal stores

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123061

The Ca(2+) channel TRPML3 regulates membrane trafficking and autophagy

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123061

The calcium channel mucolipin-3 is a novel regulator of trafficking along the endosomal pathway

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123061

NAADP mobilizes calcium from acidic organelles through two-pore channels

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123061

Motor deficit in a Drosophila model of mucolipidosis type IV due to defective clearance of apoptotic cells.

8 July 2018

1 reference

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NAADP: a universal Ca2+ trigger

8 July 2018

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Niemann-Pick disease type C1 is a sphingosine storage disease that causes deregulation of lysosomal calcium

8 July 2018

1 reference

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Molecular characterization of a novel cell surface ADP-ribosyl cyclase from the sea urchin

8 July 2018

1 reference

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TRP-ML1 functions as a lysosomal NAADP-sensitive Ca2+ release channel in coronary arterial myocytes

8 July 2018

1 reference

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Membrane traffic and turnover in TRP-ML1-deficient cells: a revised model for mucolipidosis type IV pathogenesis

8 July 2018

1 reference

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A novel mode of TRPML3 regulation by extracytosolic pH absent in the varitint-waddler phenotype

8 July 2018

1 reference

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Lysosomal trafficking functions of mucolipin-1 in murine macrophages

8 July 2018

1 reference

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A helix-breaking mutation in TRPML3 leads to constitutive activity underlying deafness in the varitint-waddler mouse

8 July 2018

1 reference

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Activating mutation in a mucolipin transient receptor potential channel leads to melanocyte loss in varitint-waddler mice.

8 July 2018

1 reference

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Gain-of-function mutation in TRPML3 causes the mouse Varitint-Waddler phenotype

8 July 2018

1 reference

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Cell-permeant NAADP: a novel chemical tool enabling the study of Ca2+ signalling in intact cells

8 July 2018

1 reference

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Polarized calcium signaling in exocrine gland cells

8 July 2018

1 reference

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Reconstitution and characterization of a nicotinic acid adenine dinucleotide phosphate (NAADP)-sensitive Ca2+ release channel from liver lysosomes of rats

8 July 2018

1 reference

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Vacuolar calcium channels.

8 July 2018

1 reference

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Mucolipin-1 is a lysosomal membrane protein required for intracellular lactosylceramide traffic

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123061

Homer 1 mediates store- and inositol 1,4,5-trisphosphate receptor-dependent translocation and retrieval of TRPC3 to the plasma membrane.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123061

Two di-leucine motifs regulate trafficking of mucolipin-1 to lysosomes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123061

TRP-ML1 regulates lysosomal pH and acidic lysosomal lipid hydrolytic activity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123061

TRP-ML1 is a lysosomal monovalent cation channel that undergoes proteolytic cleavage

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123061

Caenorhabditis elegans functional orthologue of human protein h-mucolipin-1 is required for lysosome biogenesis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123061

Calcium signalling: dynamics, homeostasis and remodelling

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123061

NAADP mobilizes Ca(2+) from reserve granules, lysosome-related organelles, in sea urchin eggs

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123061

Mutations in Mcoln3 associated with deafness and pigmentation defects in varitint-waddler (Va) mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123061

Regulation of endocytosis by CUP-5, the Caenorhabditis elegans mucolipin-1 homolog

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123061

Two different but converging messenger pathways to intracellular Ca(2+) release: the roles of nicotinic acid adenine dinucleotide phosphate, cyclic ADP-ribose and inositol trisphosphate

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123061

Abnormal transport along the lysosomal pathway in mucolipidosis, type IV disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123061

A derivative of NADP mobilizes calcium stores insensitive to inositol trisphosphate and cyclic ADP-ribose

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123061

Identification of the gene causing mucolipidosis type IV.

8 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M110.210930

The vacuolar Ca2+-activated channel TPC1 regulates germination and stomatal movement

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M110.210930

Degeneration of an intracellular ion channel in the primate lineage by relaxation of selective constraints

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21540176

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M110.210930

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21540176%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21540176%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

PubMed publication ID

21540176

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21540176%20AND%20SRC:MED&resulttype=core&format=json