Prohibitin co-localizes with Rb in the nucleus and recruits N-CoR and HDAC1 for transcriptional repression (Q24323389)

GOA release 2020-03-11

histone deacetylation

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GOA release 2020-03-11

author name string

Sheng Wang

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Gina Fusaro

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Jaya Padmanabhan

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Srikumar P Chellappan

Transcriptional control by E2F

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language of work or name

English

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publication date

5 December 2002

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8388-96

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cites work

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The cellular effects of E2F overexpression

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The retinoblastoma susceptibility gene product represses transcription when directly bound to the promoter

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Activation of SRF-regulated chromosomal templates by Rho-family GTPases requires a signal that also induces H4 hyperacetylation

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ETO, a target of t(8;21) in acute leukemia, makes distinct contacts with multiple histone deacetylases and binds mSin3A through its oligomerization domain

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Retinoblastoma protein meets chromatin

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Retinoblastoma protein recruits histone deacetylase to repress transcription

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Mammalian prohibitin proteins respond to mitochondrial stress and decrease during cellular senescence

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Nuclear receptors: coactivators, corepressors and chromatin remodeling in the control of transcription

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Linking the Rb and polycomb pathways

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A simplified formaldehyde fixation and immunoprecipitation technique for studying protein-DNA interactions

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Analysis of estrogen receptor interaction with a repressor of estrogen receptor activity (REA) and the regulation of estrogen receptor transcriptional activity by REA.

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The regulation of E2F by pRB-family proteins

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Differential regulation of Rb family proteins and prohibitin during camptothecin-induced apoptosis

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Chromatin remodeling and Rb activity

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Rb function in cell-cycle regulation and apoptosis

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Histone acetyltransferase complexes and their link to transcription

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7 January 2021

Prohibitin, an antiproliferative protein, is localized to mitochondria

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Expression of transcription factor E2F1 induces quiescent cells to enter S phase

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Role of E2F in cell cycle control and cancer

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Chromatin remodeling and transcriptional regulation

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7 January 2021

Rb interacts with histone deacetylase to repress transcription

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7 January 2021

ETO, a target of t(8;21) in acute leukemia, interacts with the N-CoR and mSin3 corepressors

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7 January 2021

Retinoblastoma protein represses transcription by recruiting a histone deacetylase

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7 January 2021

Regulation of E2F1 activity by acetylation

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7 January 2021

Prohibitin: potential role in senescence, development, and tumor suppression

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A mechanism for Rb/p130-mediated transcription repression involving recruitment of the CtBP corepressor

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An estrogen receptor-selective coregulator that potentiates the effectiveness of antiestrogens and represses the activity of estrogens

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The E2F transcription factors: key regulators of cell proliferation

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Rb targets histone H3 methylation and HP1 to promoters

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The mitochondrial PHB complex: roles in mitochondrial respiratory complex assembly, ageing and degenerative disease

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DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters

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7 January 2021

Mechanism of transcriptional repression of E2F by the retinoblastoma tumor suppressor protein.

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7 January 2021

Prohibitins regulate membrane protein degradation by the m-AAA protease in mitochondria

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7 January 2021

Immunolocalization and expression of prohibitin, a mitochondrial associated protein within the rat ovaries

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7 January 2021

Prohibitin, a potential tumor suppressor, interacts with RB and regulates E2F function

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205944

7 January 2021

Rb and prohibitin target distinct regions of E2F1 for repression and respond to different upstream signals

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205944

7 January 2021

Raf-1 physically interacts with Rb and regulates its function: a link between mitogenic signaling and cell cycle regulation

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205944

7 January 2021

Retinoblastoma protein switches the E2F site from positive to negative element

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205944

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Coactivator and corepressor complexes in nuclear receptor function

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7 January 2021

Exit from G1 and S phase of the cell cycle is regulated by repressor complexes containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205944

7 January 2021