The human MDM2 oncoprotein increases the transcriptional activity and the protein level of the p53 homolog p63. (Q40767774)

23 September 2017

title

The human MDM2 oncoprotein increases the transcriptional activity and the protein level of the p53 homolog p63. (English)

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23 September 2017

Maria Vivo

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Viola Calabrò

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Raffaele A Calogero

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Gelsomina Mansueto

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23 September 2017

Tiziana Parisi

series ordinal

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23 September 2017

Girolama La Mantia

series ordinal

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23 September 2017

language of work or name

English

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publication date

19 November 2001

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Journal of Biological Chemistry

23 September 2017

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inferred from page(s)

published in

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23 September 2017

volume

277

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23 September 2017

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23 September 2017

page(s)

2674-2681

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The p53 family: same response, different signals?

23 September 2017

cites work

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https://api.crossref.org/works/10.1074%2FJBC.M107173200

Regulation and function of the p53-related proteins: same family, different rules

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107173200

p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107173200

Cloning and functional analysis of human p51, which structurally and functionally resembles p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107173200

p73-deficient mice have neurological, pheromonal and inflammatory defects but lack spontaneous tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107173200

p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107173200

The yeast two-hybrid system reveals no interaction between p73 alpha and SV40 large T-antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107173200

p63 is a p53 homologue required for limb and epidermal morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107173200

Heterozygous germline mutations in the p53 homolog p63 are the cause of EEC syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107173200

Hay-Wells syndrome is caused by heterozygous missense mutations in the SAM domain of p63

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107173200

Nucleolar Arf sequesters Mdm2 and activates p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107173200

MDM2 suppresses p73 function without promoting p73 degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107173200

WAF1, a potential mediator of p53 tumor suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107173200

Suppression of Ras-mediated NIH3T3 transformation by p19ARF does not involve alterations of cell growth properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107173200

The human ARF cell cycle regulatory gene promoter is a CpG island which can be silenced by DNA methylation and down-regulated by wild-type p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107173200

Identification of a sequence element from p53 that signals for Mdm2-targeted degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107173200

Several hydrophobic amino acids in the p53 amino-terminal domain are required for transcriptional activation, binding to mdm-2 and the adenovirus 5 E1B 55-kD protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107173200

Mdm2 promotes the rapid degradation of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107173200

P19(ARF) stabilizes p53 by blocking nucleo-cytoplasmic shuttling of Mdm2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107173200

Regulation of p63 function by Mdm2 and MdmX.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107173200

Hdmx and Mdm2 can repress transcription activation by p53 but not by p63.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107173200

P63 and P73: P53 mimics, menaces and more

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107173200

Mdm2 binds p73 alpha without targeting degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107173200

MDM2 and MDMX bind and stabilize the p53-related protein p73

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107173200

21 January 2018

MDM2: life without p53.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107173200

MDM2--master regulator of the p53 tumor suppressor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107173200

MDM2 inhibits p300-mediated p53 acetylation and activation by forming a ternary complex with the two proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107173200

p63 and p73 transactivate differentiation gene promoters in human keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107173200

21 January 2018

Identifiers

DOI

10.1074/JBC.M107173200

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23 September 2017

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