Mechanisms controlling the temporal degradation of Nek2A and Kif18A by the APC/C-Cdc20 complex (Q24307635)

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English	Mechanisms controlling the temporal degradation of Nek2A and Kif18A by the APC/C-Cdc20 complex	scientific article

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instance of

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title

Mechanisms controlling the temporal degradation of Nek2A and Kif18A by the APC/C-Cdc20 complex (English)

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author

Mercedes Pardo

object named as

Mercedes Pardo

series ordinal

4

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Jakob Nilsson

object named as

Jakob Nilsson

series ordinal

7

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Jonathon Noe Joseph Pines

object named as

Jonathon Pines

series ordinal

6

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author name string

Garry G Sedgwick

series ordinal

1

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Daniel G Hayward

series ordinal

2

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Barbara Di Fiore

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3

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Lu Yu

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5

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language of work or name

English

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publication date

23 January 2013

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published in

The EMBO Journal

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volume

32

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issue

2

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page(s)

303-14

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cites work

UBE2S elongates ubiquitin chains on APC/C substrates to promote mitotic exit

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The APC/C maintains the spindle assembly checkpoint by targeting Cdc20 for destruction

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19 March 2017

The human kinesin Kif18A is a motile microtubule depolymerase essential for chromosome congression

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19 March 2017

Early mitotic degradation of Nek2A depends on Cdc20-independent interaction with the APC/C

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19 March 2017

An architectural map of the anaphase-promoting complex

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19 March 2017

Checkpoint protein BubR1 acts synergistically with Mad2 to inhibit anaphase-promoting complex

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Checkpoint inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2

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19 March 2017

Cyclin A is destroyed in prometaphase and can delay chromosome alignment and anaphase

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19 March 2017

Structure of the mitotic checkpoint complex

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19 March 2017

Crystal structure of the APC10/DOC1 subunit of the human anaphase-promoting complex

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19 March 2017

The spindle-assembly checkpoint in space and time

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19 March 2017

Analysis of activator-binding sites on the APC/C supports a cooperative substrate-binding mechanism.

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19 March 2017

The WD40 propeller domain of Cdh1 functions as a destruction box receptor for APC/C substrates

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PubMed Central

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19 March 2017

Doc1 mediates the activity of the anaphase-promoting complex by contributing to substrate recognition.

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PubMed Central

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19 March 2017

The Doc1 subunit is a processivity factor for the anaphase-promoting complex.

1 reference

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PubMed Central

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19 March 2017

MAD3 encodes a novel component of the spindle checkpoint which interacts with Bub3p, Cdc20p, and Mad2p

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19 March 2017

An expanded Oct4 interaction network: implications for stem cell biology, development, and disease

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19 March 2017

TPR subunits of the anaphase-promoting complex mediate binding to the activator protein CDH1

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19 March 2017

Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores

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PubMed Central

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19 March 2017

APC/C-mediated destruction of the centrosomal kinase Nek2A occurs in early mitosis and depends upon a cyclin A-type D-box

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PubMed Central

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19 March 2017

Activity of the human centrosomal kinase, Nek2, depends on an unusual leucine zipper dimerization motif

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PubMed Central

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19 March 2017

Mitotic regulation of the APC activator proteins CDC20 and CDH1

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PubMed Central

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19 March 2017

Temporal and spatial control of cyclin B1 destruction in metaphase

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7 April 2017

Dephosphorylation of Cdc20 is required for its C-box-dependent activation of the APC/C

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PubMed Central

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27 September 2017

BubR1 blocks substrate recruitment to the APC/C in a KEN-box-dependent manner.

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PubMed Central

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27 September 2017

Cdc20 control of cell fate during prolonged mitotic arrest: do Cdc20 protein levels affect cell fate in response to antimitotic compounds?

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27 September 2017

An undecided coiled coil: the leucine zipper of Nek2 kinase exhibits atypical conformational exchange dynamics

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PubMed Central

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27 September 2017

Structural basis for the subunit assembly of the anaphase-promoting complex

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27 September 2017

Affinity, avidity, and kinetics of target sequence binding to LC8 dynein light chain isoforms.

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27 September 2017

How cyclin A destruction escapes the spindle assembly checkpoint

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PubMed Central

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27 September 2017

Progressive activation of CyclinB1-Cdk1 coordinates entry to mitosis

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PubMed Central

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27 September 2017

Structure of the anaphase-promoting complex/cyclosome interacting with a mitotic checkpoint complex

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27 September 2017

Cdc20 and Cks direct the spindle checkpoint-independent destruction of cyclin A.

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27 September 2017

Mad3p, a pseudosubstrate inhibitor of APCCdc20 in the spindle assembly checkpoint

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27 September 2017

Selective small-molecule inhibitor reveals critical mitotic functions of human CDK1

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27 September 2017

Spindle checkpoint regulates Cdc20p stability in Saccharomyces cerevisiae

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27 September 2017

Human securin proteolysis is controlled by the spindle checkpoint and reveals when the APC/C switches from activation by Cdc20 to Cdh1.

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27 September 2017

Mad2-Independent inhibition of APCCdc20 by the mitotic checkpoint protein BubR1.

1 reference

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PubMed Central

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27 September 2017

Spindle checkpoint silencing requires association of PP1 to both Spc7 and kinesin-8 motors.

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30 May 2018

How APC/C-Cdc20 changes its substrate specificity in mitosis

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30 May 2018

Substrate binding on the APC/C occurs between the coactivator Cdh1 and the processivity factor Doc1.

1 reference

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PubMed Central

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30 May 2018

Structures of APC/C(Cdh1) with substrates identify Cdh1 and Apc10 as the D-box co-receptor

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30 May 2018

The APC subunit Doc1 promotes recognition of the substrate destruction box.

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Crossref

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21 January 2018

The kinesin-8 Kif18A dampens microtubule plus-end dynamics.

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21 January 2018

APC/C Cdh1 targets aurora kinase to control reorganization of the mitotic spindle at anaphase

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21 January 2018

Genomic stability and tumour suppression by the APC/C cofactor Cdh1.

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21 January 2018

A mutual inhibition between APC/C and its substrate Mes1 required for meiotic progression in fission yeast

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Crossref

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21 January 2018

Bub1 and aurora B cooperate to maintain BubR1-mediated inhibition of APC/CCdc20.

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Crossref

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21 January 2018

Cubism and the cell cycle: the many faces of the APC/C

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21 January 2018

A Role for the Fizzy/Cdc20 Family of Proteins in Activation of the APC/C Distinct from Substrate Recruitment

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retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/EMBOJ.2012.335

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PMC publication ID

3553385

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PubMed publication ID

23288039

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ResearchGate publication ID

234050642

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