Killing activity of neutrophils is mediated through activation of proteases by K+ flux (Q24292504)

Cathepsin G

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Elastase, neutrophil expressed

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Myeloperoxidase

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Elastase, neutrophil expressed

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Neutrophil cytosolic factor 1

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Cathepsin G

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ORCID Public Data File 2021

Jürgen Roes

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Anthony W Segal

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Hui Lu

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author name string

Emer P Reeves

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Hugues Lortat Jacobs

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Carlo G M Messina

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Steve Bolsover

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Giorgio Gabella

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Eric O Potma

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Alice Warley

Bactericidal activity of aerobic and anaerobic polymorphonuclear neutrophils

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language of work or name

English

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publication date

21 March 2002

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published in

Nature

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volume

416

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issue

6878

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page(s)

291-7

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cites work

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7 January 2021

Biological defense mechanisms. The production by leukocytes of superoxide, a potential bactericidal agent

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Chronic granulomatous disease

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Mice lacking neutrophil elastase reveal impaired host defense against gram negative bacterial sepsis

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Impaired immunity and enhanced resistance to endotoxin in the absence of neutrophil elastase and cathepsin G

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Involvement of superoxide and myeloperoxidase in oxygen-dependent killing of Staphylococcus aureus by neutrophils

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The effect of the inhibitor diphenylene iodonium on the superoxide-generating system of neutrophils. Specific labelling of a component polypeptide of the oxidase

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The respiratory burst of phagocytic cells is associated with a rise in vacuolar pH

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Kinetics of oxygen consumption by phagocytosing human neutrophils

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7 January 2021

Intraphagosomal chlorination dynamics and yields determined using unique fluorescent bacterial mimics

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Internal pH of human neutrophil lysosomes

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The superoxide-generating NADPH oxidase of human neutrophils is electrogenic and associated with an H+ channel

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7 January 2021

Protein kinase C activates an H+ (equivalent) conductance in the plasma membrane of human neutrophils

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7 January 2021

Simultaneous activation of NADPH oxidase-related proton and electron currents in human neutrophils.

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7 January 2021

Chloride ion efflux regulates adherence, spreading, and respiratory burst of neutrophils stimulated by tumor necrosis factor-alpha (TNF) on biologic surfaces

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7 January 2021

Production of superoxide by neutrophils: a reappraisal

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Intracellular K+, Na+ and Cl- concentrations and membrane potential in human monocytes.

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Mechanisms of phagocytosis in macrophages

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7 January 2021

Hypertonic inhibition of exocytosis in neutrophils: central role for osmotic actin skeleton remodeling

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Antibacterial activity of cationic proteins from human granulocytes

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7 January 2021

Production of the superoxide adduct of myeloperoxidase (compound III) by stimulated human neutrophils and its reactivity with hydrogen peroxide and chloride

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7 January 2021

A kinetic analysis of the catalase activity of myeloperoxidase

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7 January 2021

Pathogenic mycobacteria disrupt the macrophage actin filament network

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7 January 2021

Evidence that the product of the human X-linked CGD gene, gp91-phox, is a voltage-gated H(+) pathway

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7 January 2021

Heme histidine ligands within gp91(phox) modulate proton conduction by the phagocyte NADPH oxidase

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7 January 2021

The gp91phox component of NADPH oxidase is not the voltage-gated proton channel in phagocytes, but it helps

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7 January 2021

Hydrogen peroxide utilization in myeloperoxidase-deficient leukocytes: a possible microbicidal control mechanism

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7 January 2021

Increased atherosclerosis in myeloperoxidase-deficient mice

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7 January 2021

Purification and some properties of myeloperoxidase and eosinophil peroxidase from human blood

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Characterization of the stromal cell-derived factor-1alpha-heparin complex

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7 January 2021

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On the role of bicarbonate as a hydrogen ion buffer in rat CNS neurones

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7 January 2021