antibacterial peptide LL-37 (Q1798192)

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peptide in Homo sapiens

• LL37
• LL-37
• CAMP(134-170)

edit

Language	Label	Description	Also known as
English	antibacterial peptide LL-37	peptide in Homo sapiens	LL37 LL-37 CAMP(134-170)

Statements

instance of

peptide

0 references

protein fragment

1 reference

stated in

UniProt

part of

Antimicrobial peptides

0 references

Cathelicidin LL-37 binds to bacterial cell wall

0 references

Neutrophil degranulation

0 references

PRTN3 cleaves CAMP(31-170) to generate CAMP(134-170)

0 references

Cathelicidin antimicrobial peptide

0 references

image of molecular model or crystal lattice model

Protein CAMP PDB 2FBS.png
700 × 300; 58 KB

depicts

ribbon diagram

0 references

found in taxon

Homo sapiens

0 references

encoded by

CAMP

0 references

molecular function

protein binding

determination method or standard

IPI

1 reference

retrieved

26 September 2017

stated in

Identification of the cathelicidin peptide LL-37 as agonist for the type I insulin-like growth factor receptor

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49913&geneProductId=UniProtKB:P49913

determination method or standard

IPI

cell component

intracellular anatomical structure

determination method or standard

IDA

1 reference

retrieved

26 September 2017

stated in

The expression of the gene coding for the antibacterial peptide LL-37 is induced in human keratinocytes during inflammatory disorders

GOA

curator

UniProt

UniProt protein ID

P49913

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49913&geneProductId=UniProtKB:P49913

determination method or standard

IDA

specific granule lumen

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49913

determination method or standard

TAS

tertiary granule lumen

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49913

determination method or standard

TAS

biological process

defense response

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49913

determination method or standard

IEA

innate immune response in mucosa

determination method or standard

IDA

1 reference

retrieved

8 April 2019

stated in

Antimicrobial peptides in the first line defence of human colon mucosa

GOA

curator

UniProt

UniProt protein ID

P49913

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49913

determination method or standard

IDA

innate immune response

determination method or standard

IDA

IMP

6 references

retrieved

26 September 2017

stated in

Kallikrein-mediated proteolysis regulates the antimicrobial effects of cathelicidins in skin

GOA

curator

UniProt

UniProt protein ID

P49913

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49913&geneProductId=UniProtKB:P49913

determination method or standard

IMP

retrieved

26 September 2017

stated in

FALL-39, a putative human peptide antibiotic, is cysteine-free and expressed in bone marrow and testis

GOA

curator

UniProt

UniProt protein ID

P49913

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49913&geneProductId=UniProtKB:P49913

determination method or standard

IDA

retrieved

26 September 2017

stated in

The expression of the gene coding for the antibacterial peptide LL-37 is induced in human keratinocytes during inflammatory disorders

GOA

curator

UniProt

UniProt protein ID

P49913

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49913&geneProductId=UniProtKB:P49913

determination method or standard

IDA

retrieved

26 September 2017

stated in

Postsecretory processing generates multiple cathelicidins for enhanced topical antimicrobial defense

GOA

curator

UniProt

UniProt protein ID

P49913

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49913&geneProductId=UniProtKB:P49913

determination method or standard

IDA

retrieved

26 September 2017

stated in

The Alzheimer's disease-associated amyloid beta-protein is an antimicrobial peptide

GOA

curator

UniProt

UniProt protein ID

P49913

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49913&geneProductId=UniProtKB:P49913

determination method or standard

IDA

retrieved

26 September 2017

stated in

Processing of seminal plasma hCAP-18 to ALL-38 by gastricsin: a novel mechanism of generating antimicrobial peptides in vagina

GOA

curator

UniProt

UniProt protein ID

P49913

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49913&geneProductId=UniProtKB:P49913

determination method or standard

IDA

killing by host of symbiont cells

determination method or standard

IDA

1 reference

retrieved

8 April 2019

stated in

Keratinocyte production of cathelicidin provides direct activity against bacterial skin pathogens

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49913

determination method or standard

IDA

defense response to bacterium

determination method or standard

IEA

IMP

TAS

4 references

retrieved

8 April 2019

stated in

The human gene FALL39 and processing of the cathelin precursor to the antibacterial peptide LL-37 in granulocytes

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49913

determination method or standard

TAS

retrieved

8 April 2019

stated in

Role of defensins in corneal epithelial barrier function against Pseudomonas aeruginosa traversal

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49913

determination method or standard

IMP

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P49913

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49913

determination method or standard

IEA

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49913

determination method or standard

IEA

antimicrobial humoral response

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49913

determination method or standard

TAS

neutrophil degranulation

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49913

determination method or standard

TAS

exact match

https://www.uniprot.org/uniprot/P49913#PRO_0000004724

0 references

Identifiers

ChEBI ID

81664

0 references

Guide to Pharmacology Ligand ID

5527

0 references

KEGG ID

C18313

0 references

Reactome ID

R-HSA-1222622

0 references

R-HSA-6799515

0 references

R-HSA-6801013

0 references

Google Knowledge Graph ID

/g/1232jc_c

0 references

PDB structure ID

4EYC

1 reference

stated in

UniProt

UniProt protein ID

P49913

retrieved

9 August 2016

language of work or name

English

2FBS

1 reference

stated in

UniProt

UniProt protein ID

P49913

retrieved

9 August 2016

language of work or name

English

2FBU

1 reference

stated in

UniProt

UniProt protein ID

P49913

retrieved

9 August 2016

language of work or name

English

2FCG

1 reference

stated in

UniProt

UniProt protein ID

P49913

retrieved

9 August 2016

language of work or name

English

2K6O

1 reference

stated in

UniProt

UniProt protein ID

P49913

retrieved

9 August 2016

language of work or name

English

Semantic Scholar topic ID

2745891

0 references

 

Sitelinks

Wikipedia(2 entries)

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• dewiki LL-37
• enwiki LL37

Wikibooks(0 entries)

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Wikinews(0 entries)

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Wikiquote(0 entries)

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Wikisource(0 entries)

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Wikiversity(0 entries)

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Wikivoyage(0 entries)

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Wiktionary(0 entries)

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Multilingual sites(0 entries)

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