Pages that link to "Q27676919"
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The following pages link to Biophysical Fragment Screening of the β 1 -Adrenergic Receptor: Identification of High Affinity Arylpiperazine Leads Using Structure-Based Drug Design (Q27676919):
Displaying 50 items.
- Large-scale production and protein engineering of G protein-coupled receptors for structural studies (Q26866010) (← links)
- Substrate Deconstruction and the Nonadditivity of Enzyme Recognition (Q27683622) (← links)
- Increasing Chemical Space Coverage by Combining Empirical and Computational Fragment Screens (Q27683679) (← links)
- Function-specific virtual screening for GPCR ligands using a combined scoring method (Q28276613) (← links)
- Functional Stability of the Human Kappa Opioid Receptor Reconstituted in Nanodiscs Revealed by a Time-Resolved Scintillation Proximity Assay (Q28551129) (← links)
- Identification of Protein Palmitoylation Inhibitors from a Scaffold Ranking Library (Q28821795) (← links)
- Discovery of β2 Adrenergic Receptor Ligands Using Biosensor Fragment Screening of Tagged Wild-Type Receptor. (Q31148599) (← links)
- Allosteric sodium in class A GPCR signaling (Q33931569) (← links)
- Discovery of GPCR ligands for probing signal transduction pathways (Q34582707) (← links)
- What can crystal structures of aminergic receptors tell us about designing subtype-selective ligands? (Q34785448) (← links)
- A new crystal structure fragment-based pharmacophore method for G protein-coupled receptors (Q35305286) (← links)
- Biosensor-based affinities and binding kinetics of small molecule antagonists to the adenosine A(2A) receptor reconstituted in HDL like particles (Q35620916) (← links)
- GPCR structure, function, drug discovery and crystallography: report from Academia-Industry International Conference (UK Royal Society) Chicheley Hall, 1-2 September 2014. (Q35830953) (← links)
- Twenty years on: the impact of fragments on drug discovery (Q36078186) (← links)
- Biophysics in drug discovery: impact, challenges and opportunities. (Q36102317) (← links)
- Pharmacological Analysis and Structure Determination of 7-Methylcyanopindolol-Bound β1-Adrenergic Receptor. (Q36316813) (← links)
- SPR-based fragment screening with neurotensin receptor 1 generates novel small molecule ligands (Q36373199) (← links)
- How Can Mutations Thermostabilize G-Protein-Coupled Receptors? (Q36421791) (← links)
- New paradigms in GPCR drug discovery. (Q37140411) (← links)
- The role of a sodium ion binding site in the allosteric modulation of the A(2A) adenosine G protein-coupled receptor (Q37381287) (← links)
- Structure-based and fragment-based GPCR drug discovery (Q38172457) (← links)
- Surface plasmon resonance (SPR) biosensors in pharmaceutical analysis (Q38307244) (← links)
- Fragment optimization for GPCRs by molecular dynamics free energy calculations: Probing druggable subpockets of the A 2A adenosine receptor binding site (Q38661496) (← links)
- Developments in SPR Fragment Screening. (Q38762947) (← links)
- GPCRs through the keyhole: the role of protein flexibility in ligand binding to β-adrenoceptors. (Q38830600) (← links)
- Weak-binding molecules are not drugs?-toward a systematic strategy for finding effective weak-binding drugs. (Q38897226) (← links)
- Molecular Modelling Approaches for the Analysis of Histamine Receptors and Their Interaction with Ligands (Q39007384) (← links)
- Fluorine NMR-based screening on cell membrane extracts. (Q39294587) (← links)
- Anthocyanin rich extract of Brassica oleracea L. alleviates experimentally induced myocardial infarction. (Q41200471) (← links)
- The Role of Cholesterol in Driving IAPP-Membrane Interactions. (Q42182958) (← links)
- A mutagenesis and screening strategy to generate optimally thermostabilized membrane proteins for structural studies (Q42327908) (← links)
- Sodium ion binding pocket mutations and adenosine A2A receptor function. (Q42469733) (← links)
- What can we learn from molecular dynamics simulations for GPCR drug design? (Q43155783) (← links)
- N-{[2-(4-Phenyl-piperazin-1-yl)-ethyl]-phenyl}-arylamides with dopamine D₂ and 5-Hydroxytryptamine 5HT(1A) activity: synthesis, testing, and molecular modeling (Q44392486) (← links)
- Structure-inspired design of β-arrestin-biased ligands for aminergic GPCRs. (Q46000473) (← links)
- Towards high throughput GPCR crystallography: In Meso soaking of Adenosine A2A Receptor crystals. (Q47222471) (← links)
- Intracellular Transfer of Na+ in an Active-State G-Protein-Coupled Receptor. (Q47241989) (← links)
- Exploring GPCR-Ligand Interactions with the Fragment Molecular Orbital (FMO) Method (Q47348707) (← links)
- A Structural Framework for GPCR Chemogenomics: What's In a Residue Number? (Q47348737) (← links)
- Exploration of the antagonist CP-376395 escape pathway for the corticotropin-releasing factor receptor 1 by random acceleration molecular dynamics simulations. (Q48296107) (← links)
- In silico studies targeting G-protein coupled receptors for drug research against Parkinson's disease. (Q52665081) (← links)
- Exploring G Protein-Coupled Receptors (GPCRs) Ligand Space via Cheminformatics Approaches: Impact on Rational Drug Design. (Q53076714) (← links)
- Emerging Paradigm of Intracellular Targeting of G Protein-Coupled Receptors. (Q53819708) (← links)
- Computational design of thermostabilizing point mutations for G protein-coupled receptors. (Q55261248) (← links)
- G protein-coupled receptors: the evolution of structural insight. (Q55278334) (← links)
- High-throughput identification of G protein-coupled receptor modulators through affinity mass spectrometry screening. (Q55354388) (← links)
- Enabling STD-NMR fragment screening using stabilized native GPCR: A case study of adenosine receptor. (Q55401243) (← links)
- Structure-based virtual screening for fragment-like ligands of the G protein-coupled histamine H4 receptor (Q56991394) (← links)
- How well does cholesteryl hemisuccinate mimic cholesterol in saturated phospholipid bilayers? (Q57889017) (← links)
- Three-dimensional descriptors for aminergic GPCRs: dependence on docking conformation and crystal structure (Q62654538) (← links)