Pages that link to "Q54372999"
Jump to navigation
Jump to search
The following pages link to Evidence that DNA topoisomerase I is necessary for the cytotoxic effects of camptothecin. (Q54372999):
Displaying 50 items.
- Drugging topoisomerases: lessons and challenges (Q27000099) (← links)
- Rapamycin sensitivity in Saccharomyces cerevisiae is mediated by a peptidyl-prolyl cis-trans isomerase related to human FK506-binding protein (Q27934061) (← links)
- DNA topoisomerases and their poisoning by anticancer and antibacterial drugs (Q28284744) (← links)
- Comparison of in vitro activities of camptothecin and nitidine derivatives against fungal and cancer cells (Q28343739) (← links)
- Repair of topoisomerase-mediated DNA damage in bacteriophage T4 (Q28364144) (← links)
- Identification of the aminocatechol A-3253 as an in vitro poison of DNA topoisomerase I from Candida albicans (Q28368205) (← links)
- Pancreatic β-cell death in response to pro-inflammatory cytokines is distinct from genuine apoptosis (Q28476371) (← links)
- Decreased camptothecin sensitivity of the stem-cell-like fraction of Caco2 cells correlates with an altered phosphorylation pattern of topoisomerase I (Q28539951) (← links)
- DNA Topoisomerase I Inhibitors: Chemistry, Biology, and Interfacial Inhibition (Q29400901) (← links)
- Specific biomarkers for stochastic division patterns and starvation-induced quiescence under limited glucose levels in fission yeast (Q30501631) (← links)
- Oral topoisomerase 1 inhibitors in adult patients: present and future (Q33180133) (← links)
- Phase I and pharmacokinetic study of XR11576, an oral topoisomerase I and II inhibitor, administered on days 1-5 of a 3-weekly cycle in patients with advanced solid tumours (Q33207433) (← links)
- Phase I and pharmacological study of the new topoisomerase I inhibitor GI147211, using a daily x 5 intravenous administration (Q33495553) (← links)
- Global fitness profiling of fission yeast deletion strains by barcode sequencing (Q33600264) (← links)
- On the role of topoisomerase I in mediating the cytotoxicity of 9-aminoacridine-based anticancer agents (Q33753322) (← links)
- A novel norindenoisoquinoline structure reveals a common interfacial inhibitor paradigm for ternary trapping of the topoisomerase I-DNA covalent complex (Q33812633) (← links)
- Peptide sequencing and site-directed mutagenesis identify tyrosine-727 as the active site tyrosine of Saccharomyces cerevisiae DNA topoisomerase I. (Q33856425) (← links)
- A novel mutation in DNA topoisomerase I of yeast causes DNA damage and RAD9-dependent cell cycle arrest. (Q33960696) (← links)
- An antitumor drug-induced topoisomerase cleavage complex blocks a bacteriophage T4 replication fork in vivo (Q33961513) (← links)
- Conversion of topoisomerase I cleavage complexes on the leading strand of ribosomal DNA into 5'-phosphorylated DNA double-strand breaks by replication runoff (Q33963811) (← links)
- Bacteriophage T4 mutants hypersensitive to an antitumor agent that induces topoisomerase-DNA cleavage complexes. (Q33967883) (← links)
- SCT1 mutants suppress the camptothecin sensitivity of yeast cells expressing wild-type DNA topoisomerase I (Q34114381) (← links)
- Molecular and cytotoxic effects of camptothecin, a topoisomerase I inhibitor, on trypanosomes and Leishmania (Q34372472) (← links)
- Yeast glycosylation mutants are sensitive to aminoglycosides (Q34603353) (← links)
- Poly(ADP-ribose) polymerase and XPF–ERCC1 participate in distinct pathways for the repair of topoisomerase I-induced DNA damage in mammalian cells (Q34946954) (← links)
- Topoisomerase I is preferentially associated with normal SV40 replicative intermediates, but is associated with both replicating and nonreplicating SV40 DNAs which are deficient in histones (Q35072982) (← links)
- The Mechanism of Mus81-Mms4 Cleavage Site Selection Distinguishes It from the Homologous Endonuclease Rad1-Rad10 (Q35148358) (← links)
- Tyrosyl-DNA Phosphodiesterase 1 (Tdp1) inhibitors (Q35167579) (← links)
- Mus81-mediated DNA cleavage resolves replication forks stalled by topoisomerase I-DNA complexes (Q35670720) (← links)
- DNA repair functions that control sensitivity to topoisomerase-targeting drugs (Q35806761) (← links)
- Molecular characterization of irinotecan (SN-38) resistant human breast cancer cell lines (Q35902206) (← links)
- Tyrosyl-DNA phosphodiesterase 1 (TDP1) repairs DNA damage induced by topoisomerases I and II and base alkylation in vertebrate cells (Q35921514) (← links)
- The basis for camptothecin enhancement of DNA breakage by eukaryotic topoisomerase I. (Q35952975) (← links)
- Disruption of a topoisomerase-DNA cleavage complex by a DNA helicase (Q35955209) (← links)
- Induction of neuronal apoptosis by camptothecin, an inhibitor of DNA topoisomerase-I: evidence for cell cycle-independent toxicity (Q36237214) (← links)
- Topoisomerase I inhibitors: the relevance of prolonged exposure for present clinical development (Q36431807) (← links)
- Repair of topoisomerase I-mediated DNA damage (Q36557533) (← links)
- Topoisomerase I involvement in illegitimate recombination in Saccharomyces cerevisiae (Q36558770) (← links)
- Template topology and transcription: chromatin templates relaxed by localized linearization are transcriptionally active in yeast (Q36568321) (← links)
- Mutations in topoisomerase I as a self-resistance mechanism coevolved with the production of the anticancer alkaloid camptothecin in plants (Q36627605) (← links)
- A functional 125-kDa core polypeptide of fission yeast DNA topoisomerase II (Q36743780) (← links)
- Accelerating the discovery of biologically active small molecules using a high-throughput yeast halo assay (Q36870101) (← links)
- Immunohistochemical detection of DNA topoisomerase I in formalin fixed, paraffin wax embedded normal tissues and in ovarian carcinomas (Q37229378) (← links)
- Interfacial inhibitors: targeting macromolecular complexes (Q37968897) (← links)
- The Elephant and the Blind Men: Making Sense of PARP Inhibitors in Homologous Recombination Deficient Tumor Cells. (Q38142158) (← links)
- Differential expression of topoisomerase I and RAD52 protein in yeast reveals new facets of the mechanism of action of bisdioxopiperazine compounds (Q38273585) (← links)
- The role of topoisomerases and RNA transcription in the action of the antitumour benzonaphthyridine derivative SN 28049. (Q40028369) (← links)
- Topoisomerase I inhibitors and drug resistance (Q40028536) (← links)
- Camptothecin cytotoxicity in mammalian cells is associated with the induction of persistent double strand breaks in replicating DNA. (Q40504607) (← links)
- Yeast Saccharomyces cerevisiae as a model system to study the cytotoxic activity of the antitumor drug camptothecin (Q40694313) (← links)