Pages that link to "Q43549290"
Jump to navigation
Jump to search
The following pages link to Sequence-selective DNA binding drugs mithramycin A and chromomycin A3 are potent inhibitors of neuronal apoptosis induced by oxidative stress and DNA damage in cortical neurons (Q43549290):
Displaying 42 items.
- Targeting New Candidate Genes by Small Molecules Approaching Neurodegenerative Diseases (Q26771812) (← links)
- Epigenetic mechanisms of neurodegeneration in Huntington's disease (Q28297936) (← links)
- The crucial role of divalent metal ions in the DNA-acting efficacy and inhibition of the transcription of dimeric chromomycin A3 (Q28483713) (← links)
- Regulatory mechanism of endothelin receptor B in the cerebral arteries after focal cerebral ischemia (Q28542526) (← links)
- Egr-1 transactivates Bim gene expression to promote neuronal apoptosis (Q28564949) (← links)
- Pharmacology of epigenetics in brain disorders (Q33673025) (← links)
- Genetic diversity and striatal gene networks: focus on the heterogeneous stock-collaborative cross (HS-CC) mouse (Q33722841) (← links)
- Combined treatment of pancreatic cancer with mithramycin A and tolfenamic acid promotes Sp1 degradation and synergistic antitumor activity (Q33735387) (← links)
- Crystal structure of the [Mg2+-(chromomycin A3)2]-d(TTGGCCAA)2 complex reveals GGCC binding specificity of the drug dimer chelated by a metal ion (Q33832952) (← links)
- Deoxysugar transfer during chromomycin A3 biosynthesis in Streptomyces griseus subsp. griseus: new derivatives with antitumor activity (Q34316021) (← links)
- Novel GC-rich DNA-binding compound produced by a genetically engineered mutant of the mithramycin producer Streptomyces argillaceus exhibits improved transcriptional repressor activity: implications for cancer therapy. (Q34497376) (← links)
- Anticancer drug mithramycin interacts with core histones: An additional mode of action of the DNA groove binder (Q34585595) (← links)
- Proinflammatory Stimuli ControlN-Acylphosphatidylethanolamine-Specific Phospholipase D Expression in Macrophages (Q34715657) (← links)
- Histone deacetylase inhibitors prevent oxidative neuronal death independent of expanded polyglutamine repeats via an Sp1-dependent pathway (Q34923735) (← links)
- Combining betulinic acid and mithramycin a effectively suppresses pancreatic cancer by inhibiting proliferation, invasion, and angiogenesis (Q35632714) (← links)
- A novel mithramycin analogue with high antitumor activity and less toxicity generated by combinatorial biosynthesis (Q36090660) (← links)
- The specificity protein factor Sp1 mediates transcriptional regulation of P2X7 receptors in the nervous system (Q36492899) (← links)
- Chromatin as a target for the DNA-binding anticancer drugs. (Q36813011) (← links)
- Silencing Egr1 Attenuates Radiation-Induced Apoptosis in Normal Tissues while Killing Cancer Cells and Delaying Tumor Growth (Q36837385) (← links)
- Generation of new derivatives of the antitumor antibiotic mithramycin by altering the glycosylation pattern through combinatorial biosynthesis (Q36953571) (← links)
- Chemotherapy for the brain: the antitumor antibiotic mithramycin prolongs survival in a mouse model of Huntington's disease (Q36959352) (← links)
- Prolyl 4-hydroxylase activity-responsive transcription factors: from hydroxylation to gene expression and neuroprotection (Q36992563) (← links)
- Mithramycin is a gene-selective Sp1 inhibitor that identifies a biological intersection between cancer and neurodegeneration (Q37029655) (← links)
- Prospects and challenges for the development of new therapies for Ewing sarcoma (Q38053823) (← links)
- Transcriptional regulation of the human DNA methyltransferase 3A and 3B genes by Sp3 and Sp1 zinc finger proteins (Q38336777) (← links)
- The epigenetics of aging and neurodegeneration. (Q38527233) (← links)
- Chromomycin A2 induces autophagy in melanoma cells. (Q38931013) (← links)
- The chromomycin CmmA acetyltransferase: a membrane-bound enzyme as a tool for increasing structural diversity of the antitumour mithramycin (Q39588006) (← links)
- SP1 regulates a human SNAP-25 gene expression. (Q40025352) (← links)
- Transcriptional regulation of BACE1, the beta-amyloid precursor protein beta-secretase, by Sp1. (Q40581861) (← links)
- Premithramycinone G, an early shunt product of the mithramycin biosynthetic pathway accumulated upon inactivation of oxygenase MtmOII (Q42113467) (← links)
- Histone Deacetylase Inhibitors and Mithramycin A Impact a Similar Neuroprotective Pathway at a Crossroad between Cancer and Neurodegeneration. (Q42155982) (← links)
- Sp1 and Sp3 Are Oxidative Stress-Inducible, Antideath Transcription Factors in Cortical Neurons (Q42440875) (← links)
- Indirect readout in drug-DNA recognition: role of sequence-dependent DNA conformation (Q43042728) (← links)
- Histone Deacetylase Inhibition by Sodium Butyrate Chemotherapy Ameliorates the Neurodegenerative Phenotype in Huntington's Disease Mice (Q44619618) (← links)
- Effect of complex formation between Zn2+ ions and the anticancer drug mithramycin upon enzymatic activity of zinc(II)-dependent alcohol dehydrogenase (Q45224255) (← links)
- Inhibition of a Zn(II)-containing enzyme, alcohol dehydrogenase, by anticancer antibiotics, mithramycin and chromomycin A3. (Q46228001) (← links)
- Mithramycin A Alleviates Cognitive Deficits and Reduces Neuropathology in a Transgenic Mouse Model of Alzheimer's Disease (Q50520724) (← links)
- Manipulation of two regulatory genes for efficient production of chromomycins in Streptomyces reseiscleroticus. (Q55451092) (← links)
- Ferroptosis in Neurons and Cancer Cells Is Similar But Differentially Regulated by Histone Deacetylase Inhibitors (Q61795861) (← links)
- Inhibition of Amyloid-Beta Production, Associated Neuroinflammation, and Histone Deacetylase 2-Mediated Epigenetic Modifications Prevent Neuropathology in Alzheimer's Disease in vitro Model (Q89494061) (← links)
- Chromomycin A3 suppresses cholangiocarcinoma growth by induction of S phase cell cycle arrest and suppression of Sp1‑related anti‑apoptotic proteins (Q89989536) (← links)