Preventing AID, a physiological mutator, from deleterious activation: regulation of the genomic instability that is associated with antibody diversity (Q37704005): Difference between revisions

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Revision as of 04:02, 16 October 2022

scientific article published on 05 March 2010

Language	Label	Description	Also known as
English	Preventing AID, a physiological mutator, from deleterious activation: regulation of the genomic instability that is associated with antibody diversity	scientific article published on 05 March 2010

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

22 August 2017

1 reference

Europe PubMed Central

Preventing AID, a physiological mutator, from deleterious activation: regulation of the genomic instability that is associated with antibody diversity (English)

1 reference

Europe PubMed Central

PubMed publication ID

22 August 2017

1 reference

based on heuristic

inferred from title

5

object named as

Tasuku Honjo

1 reference

Europe PubMed Central

PubMed publication ID

22 August 2017

author name string

Hitoshi Nagaoka

1

1 reference

Europe PubMed Central

PubMed publication ID

22 August 2017

Thinh Huy Tran

2

1 reference

Europe PubMed Central

PubMed publication ID

22 August 2017

Maki Kobayashi

3

1 reference

Europe PubMed Central

PubMed publication ID

22 August 2017

Masatoshi Aida

4

1 reference

Europe PubMed Central

PubMed publication ID

22 August 2017

publication date

5 March 2010

1 reference

Europe PubMed Central

PubMed publication ID

22 August 2017

International Immunology

1 reference

Europe PubMed Central

PubMed publication ID

22 August 2017

22

1 reference

Europe PubMed Central

PubMed publication ID

22 August 2017

4

1 reference

Europe PubMed Central

PubMed publication ID

22 August 2017

227-235

1 reference

Europe PubMed Central

PubMed publication ID

22 August 2017

Expression of activation-induced cytidine deaminase in human hepatocytes via NF-kappaB signaling

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

The balance between Pax5 and Id2 activities is the key to AID gene expression

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

Mechanism and regulation of class switch recombination

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

Regulation of class switch recombination and somatic mutation by AID phosphorylation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

Infection of human B cells with Epstein-Barr virus results in the expression of somatic hypermutation-inducing molecules and in the accrual of oncogene mutations

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

AID is required for the chromosomal breaks in c-myc that lead to c-myc/IgH translocations

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

A target selection of somatic hypermutations is regulated similarly between T and B cells upon activation-induced cytidine deaminase expression

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

DNA demethylation in zebrafish involves the coupling of a deaminase, a glycosylase, and gadd45.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

C-terminal deletion of AID uncouples class switch recombination from somatic hypermutation and gene conversion.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

MicroRNA-155 is a negative regulator of activation-induced cytidine deaminase

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

Regulation of histone H4 acetylation by transcription factor E2A in Ig gene conversion.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

Palindromic but not G-rich sequences are targets of class switch recombination

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

Activation-induced cytidine deaminase: a dual role in class-switch recombination and somatic hypermutation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

Reprogramming towards pluripotency requires AID-dependent DNA demethylation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

Somatic hypermutagenesis in immunoglobulin genes. II. Influence of neighbouring base sequences on mutagenesis

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

HoxC4 binds to the promoter of the cytidine deaminase AID gene to induce AID expression, class-switch DNA recombination and somatic hypermutation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

Sibling rivalry in the E2F family

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

Separate domains of AID are required for somatic hypermutation and class-switch recombination

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

AID mediates hypermutation by deaminating single stranded DNA.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

Regulation of AID expression in the immune response

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

Organ-specific profiles of genetic changes in cancers caused by activation-induced cytidine deaminase expression

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

miR-181b negatively regulates activation-induced cytidine deaminase in B cells

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

Molecular mechanism of class switch recombination: linkage with somatic hypermutation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

AID to overcome the limitations of genomic information

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

Two levels of protection for the B cell genome during somatic hypermutation.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

MicroRNA-155 suppresses activation-induced cytidine deaminase-mediated Myc-Igh translocation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

DNA substrate length and surrounding sequence affect the activation-induced deaminase activity at cytidine

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

Beyond SHM and CSR: AID and related cytidine deaminases in the host response to viral infection

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

The mutation spectrum of purified AID is similar to the mutability index in Ramos cells and in ung(-/-)msh2(-/-) mice

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

TGF-beta signalling from cell membrane to nucleus through SMAD proteins

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

Estrogen directly activates AID transcription and function

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

Different isoforms of BSAP regulate expression of AID in normal and chronic lymphocytic leukemia B cells.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

Role of genomic instability and p53 in AID-induced c-myc-Igh translocations.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

The AID antibody diversification enzyme is regulated by protein kinase A phosphorylation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

Activation-induced cytidine deaminase expression and activity in the absence of germinal centers: insights into hyper-IgM syndrome

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

Human activation-induced cytidine deaminase causes transcription-dependent, strand-biased C to U deaminations

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

Instructive role of the transcription factor E2A in early B lymphopoiesis and germinal center B cell development

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

Viral double-stranded RNA triggers Ig class switching by activating upper respiratory mucosa B cells through an innate TLR3 pathway involving BAFF.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

Sequence dependence of chromosomal R-loops at the immunoglobulin heavy-chain Smu class switch region

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

Helicobacter pylori infection triggers aberrant expression of activation-induced cytidine deaminase in gastric epithelium

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

Proteasomal degradation restricts the nuclear lifespan of AID

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

B cell-specific and stimulation-responsive enhancers derepress Aicda by overcoming the effects of silencers

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

Regulation of hypermutation by activation-induced cytidine deaminase phosphorylation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

Activation-induced cytidine deaminase shuttles between nucleus and cytoplasm like apolipoprotein B mRNA editing catalytic polypeptide 1

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

A novel mouse model of hepatocarcinogenesis triggered by AID causing deleterious p53 mutations.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

Identification of a ubiquitously active promoter of the murine activation-induced cytidine deaminase (AICDA) gene

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

Hepatitis C virus induces a mutator phenotype: enhanced mutations of immunoglobulin and protooncogenes

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

Discriminating intrinsic and antigen-selected mutational hotspots in immunoglobulin V genes

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

AID mutant analyses indicate requirement for class-switch-specific cofactors

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

Pip, a novel IRF family member, is a lymphoid-specific, PU.1-dependent transcriptional activator

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

Regulatory mechanisms that determine the development and function of plasma cells

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

Activation-induced cytidine deaminase acts as a mutator in BCR-ABL1-transformed acute lymphoblastic leukemia cells

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

Both DNA strands of antibody genes are hypermutation targets

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

AID produces DNA double-strand breaks in non-Ig genes and mature B cell lymphomas with reciprocal chromosome translocations

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

STAT6: its role in interleukin 4-mediated biological functions

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

Recent insights into HIV-1 Vif.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

Molecular mechanisms of E2F-dependent activation and pRB-mediated repression

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

C/EBP{beta} and its binding element are required for NF{kappa}B-induced COX2 expression following hypertonic stress

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

Transcription factor Pip can enhance DNA binding by E47, leading to transcriptional synergy involving multiple protein domains

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

The B cell mutator AID promotes B lymphoid blast crisis and drug resistance in chronic myeloid leukemia

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

EBV-Encoded Latent Membrane Protein 1 Cooperates with BAFF/BLyS and APRIL to Induce T Cell-Independent Ig Heavy Chain Class Switching

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

c-Myb repression of c-erbB-2 transcription by direct binding to the c-erbB-2 promoter

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

Role of AID in tumorigenesis

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

Activation-induced cytidine deaminase (AID) promotes B cell lymphomagenesis in Emu-cmyc transgenic mice

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

APOBEC3G: an intracellular centurion

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

Mechanisms promoting translocations in editing and switching peripheral B cells

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

AID is required for germinal center-derived lymphomagenesis

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

Molecular mechanisms of antibody somatic hypermutation.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

Mutation of BCL-6 gene in normal B cells by the process of somatic hypermutation of Ig genes

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

Effect of age on the immunoglobulin class switch

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

Negative regulation of CD4 gene expression by a HES-1-c-Myb complex

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

Processive AID-catalysed cytosine deamination on single-stranded DNA simulates somatic hypermutation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

AID protein expression in chronic lymphocytic leukemia/small lymphocytic lymphoma is associated with poor prognosis and complex genetic alterations

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

Constitutive expression of AID leads to tumorigenesis

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

The AID enzyme induces class switch recombination in fibroblasts

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

Induction of activation-induced cytidine deaminase gene expression by IL-4 and CD40 ligation is dependent on STAT6 and NFkappaB.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

AID-induced decrease in topoisomerase 1 induces DNA structural alteration and DNA cleavage for class switch recombination

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

Fine-structure analysis of activation-induced deaminase accessibility to class switch region R-loops

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

The activation-induced cytidine deaminase (AID) efficiently targets DNA in nucleosomes but only during transcription

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

Recent advances in tumor necrosis factor and CD40 signaling

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

BCL-6 mutations in normal germinal center B cells: evidence of somatic hypermutation acting outside Ig loci

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

Integrity of the AID serine-38 phosphorylation site is critical for class switch recombination and somatic hypermutation in mice

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

T-independent activation-induced cytidine deaminase expression, class-switch recombination, and antibody production by immature/transitional 1 B cells

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

AID enzyme-induced hypermutation in an actively transcribed gene in fibroblasts

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

Myb binding sites within the N-ras promoter repress transcription

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

Altering the spectrum of immunoglobulin V gene somatic hypermutation by modifying the active site of AID.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1093/INTIMM/DXQ023

Transcription-targeted DNA deamination by the AID antibody diversification enzyme

0 references

Identifiers

10.1093/INTIMM/DXQ023

1 reference

Europe PubMed Central

PubMed publication ID

22 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

22 August 2017

ResearchGate publication ID

0 references

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