Revision history of "Preventing AID, a physiological mutator, from deleterious activation: regulation of the genomic instability that is associated with antibody diversity" (Q37704005)

2 March 2024

• curprev 18:5018:50, 2 March 2024 Emijrpbot talk contribs 205,471 bytes +50 ‎Changed label, description and/or aliases in fr, pt, da: BOT - Fixing descriptions (3 languages): da, fr, pt undo
• curprev 18:5018:50, 2 March 2024 Emijrpbot talk contribs 205,421 bytes +3,742 ‎Changed label, description and/or aliases in bg, bn, el, eo, es, et, fa, fi, gl, he, hu, hy, ja, ka, ko, lt, nan, nb, nn, oc, pl, pt-br, ro, ru, sq, sr-ec, sr-el, tg, tg-cyrl, th, tl, ur, vi, wuu, yue, zh, zh-cn, zh-hans, zh-hant, zh-hk, zh-mo, zh-my, zh-sg, zh-tw: BOT - Adding descriptions (44 languages): bg, bn, el, eo, es, et, fa, fi, gl, he, hu, hy, ja, ka, ko, lt, nan, nb, nn, oc, pl, pt-br, ro, ru, sq, sr-ec, sr-el, tg, tg-cyrl, th, tl, ur, vi, wuu, yue, zh, zh-cn, zh-hans, zh-hant, zh-h... undo (restore)

16 October 2022

• curprev 04:0704:07, 16 October 2022 AdrianoRutz talk contribs 201,679 bytes +1,146 ‎Added reference to claim: cites work (P2860): The C-terminal region of activation-induced cytidine deaminase is responsible for a recombination function other than DNA cleavage in class switch recombination (Q37115233), batch #101293 undo Tag: quickstatements [2.0] (restore)
• curprev 04:0704:07, 16 October 2022 AdrianoRutz talk contribs 200,533 bytes +420 ‎Created claim: cites work (P2860): The C-terminal region of activation-induced cytidine deaminase is responsible for a recombination function other than DNA cleavage in class switch recombination (Q37115233), batch #101293 undo Tag: quickstatements [2.0] (restore)
• curprev 04:0604:06, 16 October 2022 AdrianoRutz talk contribs 200,113 bytes +1,146 ‎Added reference to claim: cites work (P2860): Negative regulation of activation-induced cytidine deaminase in B cells (Q34479651), batch #101293 undo Tag: quickstatements [2.0] (restore)
• curprev 04:0604:06, 16 October 2022 AdrianoRutz talk contribs 198,967 bytes +420 ‎Created claim: cites work (P2860): Negative regulation of activation-induced cytidine deaminase in B cells (Q34479651), batch #101293 undo Tag: quickstatements [2.0] (restore)
• curprev 04:0604:06, 16 October 2022 AdrianoRutz talk contribs 198,547 bytes +1,146 ‎Added reference to claim: cites work (P2860): AID expression levels determine the extent of cMyc oncogenic translocations and the incidence of B cell tumor development (Q36853393), batch #101293 undo Tag: quickstatements [2.0] (restore)
• curprev 04:0604:06, 16 October 2022 AdrianoRutz talk contribs 197,401 bytes +420 ‎Created claim: cites work (P2860): AID expression levels determine the extent of cMyc oncogenic translocations and the incidence of B cell tumor development (Q36853393), batch #101293 undo Tag: quickstatements [2.0] (restore)
• curprev 04:0604:06, 16 October 2022 AdrianoRutz talk contribs 196,981 bytes +1,146 ‎Added reference to claim: cites work (P2860): E-proteins directly regulate expression of activation-induced deaminase in mature B cells (Q44419402), batch #101293 undo Tag: quickstatements [2.0] (restore)
• curprev 04:0604:06, 16 October 2022 AdrianoRutz talk contribs 195,835 bytes +420 ‎Created claim: cites work (P2860): E-proteins directly regulate expression of activation-induced deaminase in mature B cells (Q44419402), batch #101293 undo Tag: quickstatements [2.0] (restore)
• curprev 04:0604:06, 16 October 2022 AdrianoRutz talk contribs 195,415 bytes +1,146 ‎Added reference to claim: cites work (P2860): Biochemical analysis of hypermutational targeting by wild type and mutant activation-induced cytidine deaminase (Q40515192), batch #101293 undo Tag: quickstatements [2.0] (restore)
• curprev 04:0504:05, 16 October 2022 AdrianoRutz talk contribs 194,269 bytes +420 ‎Created claim: cites work (P2860): Biochemical analysis of hypermutational targeting by wild type and mutant activation-induced cytidine deaminase (Q40515192), batch #101293 undo Tag: quickstatements [2.0] (restore)
• curprev 04:0504:05, 16 October 2022 AdrianoRutz talk contribs 193,849 bytes +1,146 ‎Added reference to claim: cites work (P2860): Transcription enhances AID-mediated cytidine deamination by exposing single-stranded DNA on the nontemplate strand (Q28190690), batch #101293 undo Tag: quickstatements [2.0] (restore)
• curprev 04:0504:05, 16 October 2022 AdrianoRutz talk contribs 192,703 bytes +420 ‎Created claim: cites work (P2860): Transcription enhances AID-mediated cytidine deamination by exposing single-stranded DNA on the nontemplate strand (Q28190690), batch #101293 undo Tag: quickstatements [2.0] (restore)
• curprev 04:0504:05, 16 October 2022 AdrianoRutz talk contribs 192,283 bytes +1,146 ‎Added reference to claim: cites work (P2860): Activation-induced cytidine deaminase expression in gastric cancer (Q46662259), batch #101293 undo Tag: quickstatements [2.0] (restore)
• curprev 04:0504:05, 16 October 2022 AdrianoRutz talk contribs 191,137 bytes +420 ‎Created claim: cites work (P2860): Activation-induced cytidine deaminase expression in gastric cancer (Q46662259), batch #101293 undo Tag: quickstatements [2.0] (restore)
• curprev 04:0504:05, 16 October 2022 AdrianoRutz talk contribs 190,717 bytes +1,146 ‎Added reference to claim: cites work (P2860): Expression of AID transgene is regulated in activated B cells but not in resting B cells and kidney (Q38291974), batch #101293 undo Tag: quickstatements [2.0] (restore)
• curprev 04:0504:05, 16 October 2022 AdrianoRutz talk contribs 189,571 bytes +420 ‎Created claim: cites work (P2860): Expression of AID transgene is regulated in activated B cells but not in resting B cells and kidney (Q38291974), batch #101293 undo Tag: quickstatements [2.0] (restore)
• curprev 04:0504:05, 16 October 2022 AdrianoRutz talk contribs 189,151 bytes +1,146 ‎Added reference to claim: cites work (P2860): Mimicry of CD40 signals by Epstein-Barr virus LMP1 in B lymphocyte responses (Q45746898), batch #101293 undo Tag: quickstatements [2.0] (restore)
• curprev 04:0504:05, 16 October 2022 AdrianoRutz talk contribs 188,005 bytes +420 ‎Created claim: cites work (P2860): Mimicry of CD40 signals by Epstein-Barr virus LMP1 in B lymphocyte responses (Q45746898), batch #101293 undo Tag: quickstatements [2.0] (restore)
• curprev 04:0504:05, 16 October 2022 AdrianoRutz talk contribs 187,585 bytes +1,146 ‎Added reference to claim: cites work (P2860): Cutting edge: DGYW/WRCH is a better predictor of mutability at G:C bases in Ig hypermutation than the widely accepted RGYW/WRCY motif and probably reflects a two-step activation-induced cytidine deaminase-triggered process (Q33198930), batch #101293 undo Tag: quickstatements [2.0] (restore)
• curprev 04:0504:05, 16 October 2022 AdrianoRutz talk contribs 186,439 bytes +420 ‎Created claim: cites work (P2860): Cutting edge: DGYW/WRCH is a better predictor of mutability at G:C bases in Ig hypermutation than the widely accepted RGYW/WRCY motif and probably reflects a two-step activation-induced cytidine deaminase-triggered process (Q33198930), batch #101293 undo Tag: quickstatements [2.0] (restore)
• curprev 04:0504:05, 16 October 2022 AdrianoRutz talk contribs 186,019 bytes +1,146 ‎Added reference to claim: cites work (P2860): B-cell receptor activation inhibits AID expression through calmodulin inhibition of E-proteins (Q36446170), batch #101293 undo Tag: quickstatements [2.0] (restore)
• curprev 04:0504:05, 16 October 2022 AdrianoRutz talk contribs 184,873 bytes +420 ‎Created claim: cites work (P2860): B-cell receptor activation inhibits AID expression through calmodulin inhibition of E-proteins (Q36446170), batch #101293 undo Tag: quickstatements [2.0] (restore)
• curprev 04:0504:05, 16 October 2022 AdrianoRutz talk contribs 184,453 bytes +1,146 ‎Added reference to claim: cites work (P2860): Different isoforms of the B-cell mutator activation-induced cytidine deaminase are aberrantly expressed in BCR-ABL1-positive acute lymphoblastic leukemia patients. (Q43275641), batch #101293 undo Tag: quickstatements [2.0] (restore)
• curprev 04:0504:05, 16 October 2022 AdrianoRutz talk contribs 183,307 bytes +420 ‎Created claim: cites work (P2860): Different isoforms of the B-cell mutator activation-induced cytidine deaminase are aberrantly expressed in BCR-ABL1-positive acute lymphoblastic leukemia patients. (Q43275641), batch #101293 undo Tag: quickstatements [2.0] (restore)
• curprev 04:0504:05, 16 October 2022 AdrianoRutz talk contribs 182,887 bytes +1,146 ‎Added reference to claim: cites work (P2860): Regulation of the germinal center gene program by interferon (IFN) regulatory factor 8/IFN consensus sequence-binding protein (Q36227838), batch #101293 undo Tag: quickstatements [2.0] (restore)
• curprev 04:0404:04, 16 October 2022 AdrianoRutz talk contribs 181,741 bytes +420 ‎Created claim: cites work (P2860): Regulation of the germinal center gene program by interferon (IFN) regulatory factor 8/IFN consensus sequence-binding protein (Q36227838), batch #101293 undo Tag: quickstatements [2.0] (restore)
• curprev 04:0404:04, 16 October 2022 AdrianoRutz talk contribs 181,321 bytes +1,146 ‎Added reference to claim: cites work (P2860): Nonclassic functions of human topoisomerase I: genome-wide and pharmacologic analyses (Q40079482), batch #101293 undo Tag: quickstatements [2.0] (restore)
• curprev 04:0404:04, 16 October 2022 AdrianoRutz talk contribs 180,175 bytes +419 ‎Created claim: cites work (P2860): Nonclassic functions of human topoisomerase I: genome-wide and pharmacologic analyses (Q40079482), batch #101293 undo Tag: quickstatements [2.0] (restore)
• curprev 04:0404:04, 16 October 2022 AdrianoRutz talk contribs 179,756 bytes +1,146 ‎Added reference to claim: cites work (P2860): Impact of phosphorylation and phosphorylation-null mutants on the activity and deamination specificity of activation-induced cytidine deaminase (Q33328760), batch #101293 undo Tag: quickstatements [2.0] (restore)
• curprev 04:0404:04, 16 October 2022 AdrianoRutz talk contribs 178,610 bytes +419 ‎Created claim: cites work (P2860): Impact of phosphorylation and phosphorylation-null mutants on the activity and deamination specificity of activation-induced cytidine deaminase (Q33328760), batch #101293 undo Tag: quickstatements [2.0] (restore)
• curprev 04:0404:04, 16 October 2022 AdrianoRutz talk contribs 178,191 bytes +1,146 ‎Added reference to claim: cites work (P2860): Conformational variants of duplex DNA correlated with cytosine-rich chromosomal fragile sites. (Q43167080), batch #101293 undo Tag: quickstatements [2.0] (restore)
• curprev 04:0404:04, 16 October 2022 AdrianoRutz talk contribs 177,045 bytes +419 ‎Created claim: cites work (P2860): Conformational variants of duplex DNA correlated with cytosine-rich chromosomal fragile sites. (Q43167080), batch #101293 undo Tag: quickstatements [2.0] (restore)
• curprev 04:0304:03, 16 October 2022 AdrianoRutz talk contribs 176,626 bytes +1,146 ‎Added reference to claim: cites work (P2860): The Targeting of Somatic Hypermutation Closely Resembles That of Meiotic Mutation (Q57234192), batch #101293 undo Tag: quickstatements [2.0] (restore)
• curprev 04:0304:03, 16 October 2022 AdrianoRutz talk contribs 175,480 bytes +419 ‎Created claim: cites work (P2860): The Targeting of Somatic Hypermutation Closely Resembles That of Meiotic Mutation (Q57234192), batch #101293 undo Tag: quickstatements [2.0] (restore)
• curprev 04:0304:03, 16 October 2022 AdrianoRutz talk contribs 175,061 bytes +1,146 ‎Added reference to claim: cites work (P2860): Activation-induced cytidine deaminase deaminates 5-methylcytosine in DNA and is expressed in pluripotent tissues: implications for epigenetic reprogramming (Q28284694), batch #101293 undo Tag: quickstatements [2.0] (restore)
• curprev 04:0304:03, 16 October 2022 AdrianoRutz talk contribs 173,915 bytes +419 ‎Created claim: cites work (P2860): Activation-induced cytidine deaminase deaminates 5-methylcytosine in DNA and is expressed in pluripotent tissues: implications for epigenetic reprogramming (Q28284694), batch #101293 undo Tag: quickstatements [2.0] (restore)
• curprev 04:0304:03, 16 October 2022 AdrianoRutz talk contribs 173,496 bytes +1,146 ‎Added reference to claim: cites work (P2860): Viral induction of AID is independent of the interferon and the Toll-like receptor signaling pathways but requires NF-kappaB. (Q36229720), batch #101293 undo Tag: quickstatements [2.0] (restore)
• curprev 04:0304:03, 16 October 2022 AdrianoRutz talk contribs 172,350 bytes +419 ‎Created claim: cites work (P2860): Viral induction of AID is independent of the interferon and the Toll-like receptor signaling pathways but requires NF-kappaB. (Q36229720), batch #101293 undo Tag: quickstatements [2.0] (restore)
• curprev 04:0304:03, 16 October 2022 AdrianoRutz talk contribs 171,931 bytes +1,146 ‎Added reference to claim: cites work (P2860): Discovery of activation-induced cytidine deaminase, the engraver of antibody memory (Q36845653), batch #101293 undo Tag: quickstatements [2.0] (restore)
• curprev 04:0304:03, 16 October 2022 AdrianoRutz talk contribs 170,785 bytes +419 ‎Created claim: cites work (P2860): Discovery of activation-induced cytidine deaminase, the engraver of antibody memory (Q36845653), batch #101293 undo Tag: quickstatements [2.0] (restore)
• curprev 04:0204:02, 16 October 2022 AdrianoRutz talk contribs 170,366 bytes +1,146 ‎Added reference to claim: cites work (P2860): AID-deficient Bcl-xL transgenic mice develop delayed atypical plasma cell tumors with unusual Ig/Myc chromosomal rearrangements (Q36229165), batch #101293 undo Tag: quickstatements [2.0] (restore)
• curprev 04:0204:02, 16 October 2022 AdrianoRutz talk contribs 169,220 bytes +419 ‎Created claim: cites work (P2860): AID-deficient Bcl-xL transgenic mice develop delayed atypical plasma cell tumors with unusual Ig/Myc chromosomal rearrangements (Q36229165), batch #101293 undo Tag: quickstatements [2.0] (restore)
• curprev 04:0204:02, 16 October 2022 AdrianoRutz talk contribs 168,801 bytes +1,146 ‎Added reference to claim: cites work (P2860): Transcription-targeted DNA deamination by the AID antibody diversification enzyme (Q28190732), batch #101293 undo Tag: quickstatements [2.0] (restore)
• curprev 04:0204:02, 16 October 2022 AdrianoRutz talk contribs 167,655 bytes +419 ‎Created claim: cites work (P2860): Transcription-targeted DNA deamination by the AID antibody diversification enzyme (Q28190732), batch #101293 undo Tag: quickstatements [2.0] (restore)
• curprev 04:0204:02, 16 October 2022 AdrianoRutz talk contribs 167,236 bytes +1,146 ‎Added reference to claim: cites work (P2860): Altering the spectrum of immunoglobulin V gene somatic hypermutation by modifying the active site of AID. (Q39756116), batch #101293 undo Tag: quickstatements [2.0] (restore)
• curprev 04:0204:02, 16 October 2022 AdrianoRutz talk contribs 166,090 bytes +419 ‎Created claim: cites work (P2860): Altering the spectrum of immunoglobulin V gene somatic hypermutation by modifying the active site of AID. (Q39756116), batch #101293 undo Tag: quickstatements [2.0] (restore)
• curprev 04:0204:02, 16 October 2022 AdrianoRutz talk contribs 165,671 bytes +1,146 ‎Added reference to claim: cites work (P2860): Myb binding sites within the N-ras promoter repress transcription (Q42442216), batch #101293 undo Tag: quickstatements [2.0] (restore)
• curprev 04:0204:02, 16 October 2022 AdrianoRutz talk contribs 164,525 bytes +419 ‎Created claim: cites work (P2860): Myb binding sites within the N-ras promoter repress transcription (Q42442216), batch #101293 undo Tag: quickstatements [2.0] (restore)