DLX1 acts as a crucial target of FOXM1 to promote ovarian cancer aggressiveness by enhancing TGF-β/SMAD4 signaling (Q37697488)

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scientific article published on 05 September 2016

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English	DLX1 acts as a crucial target of FOXM1 to promote ovarian cancer aggressiveness by enhancing TGF-β/SMAD4 signaling	scientific article published on 05 September 2016

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scholarly article

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22 August 2017

DLX1 acts as a crucial target of FOXM1 to promote ovarian cancer aggressiveness by enhancing TGF-β/SMAD4 signaling (English)

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22 August 2017

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13 June 2020

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13 June 2020

Hextan Y S Ngan

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13 June 2020

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D W Chan

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W W Y Hui

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L M N Hui

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Y Qin

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R R Liang

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T H Y Leung

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D Xu

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K K L Chan

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K-M Yao

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B K Tsang

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5 September 2016

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22 August 2017

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13 June 2020

1404-1416

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13 June 2020

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Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International

5 September 2016

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TGFβ Signaling in Tumor Initiation, Epithelial-to-Mesenchymal Transition, and Metastasis

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23 August 2017

Overexpression of FOXM1 predicts poor prognosis and promotes cancer cell proliferation, migration and invasion in epithelial ovarian cancer

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23 August 2017

Sustained activation of SMAD3/SMAD4 by FOXM1 promotes TGF-β-dependent cancer metastasis

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23 August 2017

FOXM1b, which is present at elevated levels in cancer cells, has a greater transforming potential than FOXM1c.

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23 August 2017

Genome-wide mapping of FOXM1 binding reveals co-binding with estrogen receptor alpha in breast cancer cells

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23 August 2017

Targeting GRB7/ERK/FOXM1 signaling pathway impairs aggressiveness of ovarian cancer cells

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23 August 2017

DLX4 upregulates TWIST and enhances tumor migration, invasion and metastasis

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A novel FoxM1-caveolin signaling pathway promotes pancreatic cancer invasion and metastasis

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23 August 2017

Aberrant activation of ERK/FOXM1 signaling cascade triggers the cell migration/invasion in ovarian cancer cells

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23 August 2017

Integrated genomic analyses of ovarian carcinoma

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ChIP-Array: combinatory analysis of ChIP-seq/chip and microarray gene expression data to discover direct/indirect targets of a transcription factor

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Over-expression of FoxM1 leads to epithelial-mesenchymal transition and cancer stem cell phenotype in pancreatic cancer cells

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23 August 2017

Up-regulation of homeodomain genes, DLX1 and DLX2, by FLT3 signaling

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23 August 2017

Homeodomain protein DLX4 counteracts key transcriptional control mechanisms of the TGF-β cytostatic program and blocks the antiproliferative effect of TGF-β

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Deregulation of FoxM1b leads to tumour metastasis

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Mutually exclusive expression of DLX2 and DLX5/6 is associated with the metastatic potential of the human breast cancer cell line MDA-MB-231

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23 August 2017

Upregulation of DLX5 promotes ovarian cancer cell proliferation by enhancing IRS-2-AKT signaling

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The regulation of TGFbeta signal transduction

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23 August 2017

Overexpression of FOXG1 contributes to TGF-beta resistance through inhibition of p21WAF1/CIP1 expression in ovarian cancer

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23 August 2017

Generation of Cre-transgenic mice using Dlx1/Dlx2 enhancers and their characterization in GABAergic interneurons

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FoxM1B transcriptionally regulates vascular endothelial growth factor expression and promotes the angiogenesis and growth of glioma cells

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Dlx transcription factors promote migration through repression of axon and dendrite growth

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23 August 2017

A homeobox gene related to Drosophila distal-less promotes ovarian tumorigenicity by inducing expression of vascular endothelial growth factor and fibroblast growth factor-2

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23 August 2017

A cell-penetrating ARF peptide inhibitor of FoxM1 in mouse hepatocellular carcinoma treatment

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23 August 2017

FoxM1: at the crossroads of ageing and cancer

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Transforming growth factor-beta in cancer and metastasis

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Hematopoiesis controlled by distinct TIF1gamma and Smad4 branches of the TGFbeta pathway

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TRANSFAC and its module TRANSCompel: transcriptional gene regulation in eukaryotes

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Mice lacking Dlx1 show subtype-specific loss of interneurons, reduced inhibition and epilepsy

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FoxM1: a master regulator of tumor metastasis

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