Targeting the leukemia microenvironment by CXCR4 inhibition overcomes resistance to kinase inhibitors and chemotherapy in AML. (Q37234641)

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scientific article published on 27 October 2008

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English	Targeting the leukemia microenvironment by CXCR4 inhibition overcomes resistance to kinase inhibitors and chemotherapy in AML.	scientific article published on 27 October 2008

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instance of

scholarly article

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Europe PubMed Central

PMC publication ID

2699240

retrieved

19 August 2017

title

Targeting the leukemia microenvironment by CXCR4 inhibition overcomes resistance to kinase inhibitors and chemotherapy in AML. (English)

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Europe PubMed Central

PMC publication ID

2699240

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19 August 2017

main subject

chemotherapy

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inferred from title

leukemia

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inferred from title

author

Marina Konopleva

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13

object named as

Marina Konopleva

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Europe PubMed Central

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19 August 2017

PMC publication ID

2699240

Michael Andreeff

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Michael Andreeff

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Europe PubMed Central

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19 August 2017

PMC publication ID

2699240

Elihu Estey

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Elihu H Estey

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Europe PubMed Central

PMC publication ID

2699240

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19 August 2017

Mark J Levis

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Mark Levis

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PMC publication ID

2699240

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19 August 2017

Ismael Samudio

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Ismael J Samudio

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2699240

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19 August 2017

Xiaoyang Ling

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Xiaoyang Ling

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PMC publication ID

2699240

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19 August 2017

Sergej Konoplev

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Sergej Konoplev

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2699240

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19 August 2017

Zhihong Zeng

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Zhihong Zeng

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2699240

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19 August 2017

author name string

Yue Xi Shi

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2

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PMC publication ID

2699240

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19 August 2017

Rui-Yu Wang

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4

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2699240

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19 August 2017

Olga Frolova

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2699240

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19 August 2017

Joshua B Rubin

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8

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2699240

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19 August 2017

Robert R Negrin

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9

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2699240

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19 August 2017

language of work or name

English

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publication date

27 October 2008

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Europe PubMed Central

PMC publication ID

2699240

retrieved

19 August 2017

published in

Blood

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PMC publication ID

2699240

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19 August 2017

volume

113

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19 August 2017

issue

24

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2699240

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19 August 2017

page(s)

6215-6224

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2699240

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19 August 2017

describes a project that uses

ImageQuant

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11 June 2022

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2699240/fullTextXML

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Human bone marrow stromal cells prevent apoptosis and support the survival of chronic lymphocytic leukaemia cells in vitro

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Integrin function in chronic lymphocytic leukemia

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Chronic lymphocytic leukemic B cells but not normal B cells are rescued from apoptosis by contact with normal bone marrow stromal cells

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Changing bone marrow micro-environment during development of acute myeloid leukaemia in rats

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The chemokine receptor CXCR4 is required for the retention of B lineage and granulocytic precursors within the bone marrow microenvironment

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A highly sensitive strategy for SCID-repopulating cell assay by direct injection of primitive human hematopoietic cells into NOD/SCID mice bone marrow

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Perspectives: signal transduction. Cell survival demands some Rsk

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Functional response of leukaemic blasts to stromal cell-derived factor-1 correlates with preferential expression of the chemokine receptor CXCR4 in acute myelomonocytic and lymphoblastic leukaemia

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Stability and prognostic influence of FLT3 mutations in paired initial and relapsed AML samples

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Overexpression of CXCR4 predicts adverse overall and event-free survival in patients with unmutated FLT3 acute myeloid leukemia with normal karyotype

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Combining SDF-1/CXCR4 antagonism and chemotherapy in relapsed acute myeloid leukemia

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12 December 2020

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Identifiers

DOI

10.1182/BLOOD-2008-05-158311

1 reference

stated in

Europe PubMed Central

PMC publication ID

2699240

retrieved

19 August 2017

PMC publication ID

2699240

1 reference

stated in

Europe PubMed Central

PMC publication ID

2699240

retrieved

19 August 2017

PubMed publication ID

18955566

1 reference

stated in

Europe PubMed Central

PMC publication ID

2699240

retrieved

19 August 2017

ResearchGate publication ID

23423346

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