Evidence that inositol polyphosphate 4-phosphatase type II is a tumor suppressor that inhibits PI3K signaling (Q34212404)

31 July 2017

title

Evidence that inositol polyphosphate 4-phosphatase type II is a tumor suppressor that inhibits PI3K signaling (English)

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31 July 2017

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31 July 2017

Julie Teruya-Feldstein

object named as

Julie Teruya-Feldstein

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Pier Paolo Pandolfi

object named as

Pier Paolo Pandolfi

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David Bowtell

object named as

David Bowtell

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31 July 2017

Leonardo Salmena

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31 July 2017

Christina Gewinner

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31 July 2017

Zhigang C Wang

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31 July 2017

Andrea Richardson

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31 July 2017

Dariush Etemadmoghadam

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31 July 2017

Jordi Barretina

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31 July 2017

William M Lin

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31 July 2017

Lucia Rameh

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31 July 2017

publication date

1 August 2009

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31 July 2017

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31 July 2017

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31 July 2017

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31 July 2017

page(s)

115-125

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Integrated genome-wide DNA copy number and expression analysis identifies distinct mechanisms of primary chemoresistance in ovarian carcinomas

31 July 2017

cites work

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Akt determines replicative senescence and oxidative or oncogenic premature senescence and sensitizes cells to oxidative apoptosis

5 July 2018

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The deubiquitinylation and localization of PTEN are regulated by a HAUSP-PML network

5 July 2018

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Modeling genomic diversity and tumor dependency in malignant melanoma

5 July 2018

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Recurrent gross mutations of the PTEN tumor suppressor gene in breast cancers with deficient DSB repair.

5 July 2018

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Serum withdrawal-induced accumulation of phosphoinositide 3-kinase lipids in differentiating 3T3-L6 myoblasts: distinct roles for Ship2 and PTEN.

5 July 2018

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High resolution melting for mutation scanning of TP53 exons 5-8

5 July 2018

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AKT/PKB signaling: navigating downstream

5 July 2018

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A new mouse model to explore the initiation, progression, and therapy of BRAFV600E-induced lung tumors

5 July 2018

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Discovery and validation of breast cancer subtypes

5 July 2018

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Distinct patterns of DNA copy number alteration are associated with different clinicopathological features and gene-expression subtypes of breast cancer

5 July 2018

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The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism

5 July 2018

1 reference

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Regulation of protein kinase B activity by PTEN and SHIP2 in human prostate-derived cell lines

5 July 2018

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The epithelial-mesenchymal transition: new insights in signaling, development, and disease

5 July 2018

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X chromosomal abnormalities in basal-like human breast cancer

5 July 2018

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High resolution genomic analysis of sporadic breast cancer using array-based comparative genomic hybridization

5 July 2018

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Akt-dependent transformation: there is more to growth than just surviving

5 July 2018

1 reference

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Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis

5 July 2018

1 reference

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Tumour biology: senescence in premalignant tumours

5 July 2018

1 reference

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A genetic screen for candidate tumor suppressors identifies REST

5 July 2018

1 reference

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Absence of the lipid phosphatase SHIP2 confers resistance to dietary obesity

5 July 2018

1 reference

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Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures

5 July 2018

1 reference

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Physiological functions of Pten in mouse tissues

5 July 2018

1 reference

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The phosphatidylinositol 3-Kinase AKT pathway in human cancer

5 July 2018

1 reference

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Modelling the molecular circuitry of cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957372

The phosphoinositide 3-kinase pathway

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957372

Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957372

Phosphatidylinositol 3' kinase signaling in mammary tumorigenesis.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957372

The PTEN tumor suppressor protein: an antagonist of phosphoinositide 3-kinase signaling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957372

Pten is essential for embryonic development and tumour suppression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957372

The cDNA cloning and characterization of inositol polyphosphate 4-phosphatase type II. Evidence for conserved alternative splicing in the 4-phosphatase family

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957372

Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957372

A specific product of phosphatidylinositol 3-kinase directly activates the protein kinase Akt through its pleckstrin homology domain.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957372

A stable human-derived packaging cell line for production of high titer retrovirus/vesicular stomatitis virus G pseudotypes

5 July 2018

1 reference

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The Isolation and Characterization of cDNA Encoding Human and Rat Brain Inositol Polyphosphate 4-Phosphatase

5 July 2018

1 reference

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A biomarker that identifies senescent human cells in culture and in aging skin in vivo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957372

Evidence for two distinct phosphatidylinositol kinases in fibroblasts. Implications for cellular regulation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957372

PDGF-dependent tyrosine phosphorylation stimulates production of novel polyphosphoinositides in intact cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957372

Small-molecule agonists of SHIP1 inhibit the phosphoinositide 3-kinase pathway in hematopoietic cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957372

A negative feedback signaling network underlies oncogene-induced senescence

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957372

Using array-comparative genomic hybridization to define molecular portraits of primary breast cancers.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957372

Mutational and LOH analyses of the chromosome 4q region in esophageal adenocarcinoma.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957372

Phosphatidylinositol 4-phosphatase type II is an erythropoietin-responsive gene.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957372

Oncogene-induced senescence as an initial barrier in lymphoma development

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957372

Deletions on chromosome 4 in sporadic and BRCA mutated tumors and association with pathological variables

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957372

Phosphatidylinositol (3,4,5)P3 is essential but not sufficient for protein kinase B (PKB) activation; phosphatidylinositol (3,4)P2 is required for PKB phosphorylation at Ser-473: studies using cells from SH2-containing inositol-5-phosphatase knockou

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957372

Human mammary epithelial cell transformation through the activation of phosphatidylinositol 3-kinase

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19647222

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

High Affinity Binding of Inositol Phosphates and Phosphoinositides to the Pleckstrin Homology Domain of RAC/Protein Kinase B and Their Influence on Kinase Activity

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19647222

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Gene structure, expression profiling and mutation analysis of the tumour suppressor SHIP1 in Caucasian acute myeloid leukaemia

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19647222

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CCR.2009.06.006

1 reference

31 July 2017

1 reference

31 July 2017

1 reference