The forkhead transcription factor Foxo1 links insulin signaling to Pdx1 regulation of pancreatic beta cell growth (Q28508976)

24 January 2017

title

The forkhead transcription factor Foxo1 links insulin signaling to Pdx1 regulation of pancreatic beta cell growth (English)

1 reference

24 January 2017

1 reference

Insulin II

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Forkhead box A2

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Insulin receptor substrate 2

1 reference

Forkhead box O1

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Pancreatic and duodenal homeobox 1

1 reference

1 reference

1 reference

Domenico Accili

1 reference

24 January 2017

Tadahiro Kitamura

1 reference

24 January 2017

Jun Nakae

1 reference

24 January 2017

Yukari Kitamura

1 reference

24 January 2017

Yoshiaki Kido

1 reference

24 January 2017

William H. Biggs

1 reference

24 January 2017

Christopher V. E. Wright

1 reference

24 January 2017

Morris F. White

1 reference

24 January 2017

Karen C. Arden

1 reference

24 January 2017

language of work or name

English

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publication date

1 December 2002

1 reference

Journal of Clinical Investigation

24 January 2017

published in

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24 January 2017

volume

110

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24 January 2017

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24 January 2017

page(s)

1839–1847

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Pbx1 inactivation disrupts pancreas development and in Ipf1-deficient mice promotes diabetes mellitus

24 January 2017

cites work

1 reference

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19 March 2017

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The forkhead transcription factor Foxo1 (Fkhr) confers insulin sensitivity onto glucose-6-phosphatase expression

19 March 2017

1 reference

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Forkhead homologue in rhabdomyosarcoma functions as a bifunctional nuclear receptor-interacting protein with both coactivator and corepressor functions

19 March 2017

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Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1

19 March 2017

1 reference

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AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1

19 March 2017

1 reference

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Unified nomenclature for the winged helix/forkhead transcription factors

19 March 2017

1 reference

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Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

19 March 2017

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Disruption of IRS-2 causes type 2 diabetes in mice

19 March 2017

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Hormonal regulation of an islet-specific enhancer in the pancreatic homeobox gene STF-1

19 March 2017

1 reference

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Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells

19 March 2017

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Cellular survival: a play in three Akts

19 March 2017

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Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors

7 April 2017

1 reference

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Defective insulin secretion in pancreatic beta cells lacking type 1 IGF receptor

7 April 2017

1 reference

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Regulation of insulin action and pancreatic beta-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1.

29 September 2017

1 reference

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Pdx1 restores beta cell function in Irs2 knockout mice

29 September 2017

1 reference

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Diabetes mellitus and genetically programmed defects in beta-cell function

29 September 2017

1 reference

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A kinase in the life of the beta cell

29 September 2017

1 reference

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Preserved pancreatic beta-cell development and function in mice lacking the insulin receptor-related receptor

29 September 2017

1 reference

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Life and death of the pancreatic beta cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151657

Functional conservation of regulatory elements in the pdx-1 gene: PDX-1 and hepatocyte nuclear factor 3beta transcription factors mediate beta-cell-specific expression

29 September 2017

1 reference

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In vitro cultivation of human islets from expanded ductal tissue

29 September 2017

1 reference

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Hepatocyte nuclear factor 3beta is involved in pancreatic beta-cell-specific transcription of the pdx-1 gene

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151657

The insulin-pancreatic acinar axis

29 September 2017

1 reference

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Islet cells as a component of pancreatic ductal neoplasms. I. Experimental study: ductular cells, including islet cell precursors, as primary progenitor cells of tumors

29 September 2017

1 reference

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The IRS-2 gene on murine chromosome 8 encodes a unique signaling adapter for insulin and cytokine action.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151657

Foxa2 controls Pdx1 gene expression in pancreatic beta-cells in vivo.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151657

beta-cell-specific deletion of the Igf1 receptor leads to hyperinsulinemia and glucose intolerance but does not alter beta-cell mass

27 November 2018

1 reference

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Reduction in pancreatic transcription factor PDX-1 impairs glucose-stimulated insulin secretion

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151657

Regeneration of pancreatic beta cells from intra-islet precursor cells in an experimental model of diabetes

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151657

Disruption of insulin receptor substrate 2 causes type 2 diabetes because of liver insulin resistance and lack of compensatory beta-cell hyperplasia.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151657

Developmental expression of the homeodomain protein IDX-1 in mice transgenic for an IDX-1 promoter/lacZ transcriptional reporter.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151657

Irs-2 coordinates Igf-1 receptor-mediated beta-cell development and peripheral insulin signalling.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151657

Insulin stimulates phosphorylation of the forkhead transcription factor FKHR on serine 253 through a Wortmannin-sensitive pathway

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151657

Tissue-specific knockout of the insulin receptor in pancreatic beta cells creates an insulin secretory defect similar to that in type 2 diabetes.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151657

Association between islets of Langerhans and pancreatic ductal system in adult rat. Where endocrine and exocrine meet together?

27 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/12488434

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Characterization of immunoreactive components of insulin and somatostatin in canine pancreatic juice

1 reference

https://pubmed.ncbi.nlm.nih.gov/12488434

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Insulin administration enhances growth of the beta-cell mass in streptozotocin-treated newborn rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/12488434

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

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24 January 2017

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