T cell antigen CD28 binds to the GRB-2/SOS complex, regulators of p21ras (Q28300793)

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scientific article

Language	Label	Description	Also known as
English	T cell antigen CD28 binds to the GRB-2/SOS complex, regulators of p21ras	scientific article

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scholarly article

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T cell antigen CD28 binds to the GRB-2/SOS complex, regulators of p21ras (English)

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author name string

H Schneider

1

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Y C Cai

2

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K V Prasad

3

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S E Shoelson

4

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C E Rudd

5

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language of work or name

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publication date

April 1995

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European Journal of Immunology

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25

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4

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1044-50

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The role of the CD28 receptor during T cell responses to antigen

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Activation of Ras in vitro and in intact fibroblasts by the Vav guanine nucleotide exchange protein

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Dbl and Vav mediate transformation via mitogen-activated protein kinase pathways that are distinct from those activated by oncogenic Ras

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The NFAT-1 DNA binding complex in activated T cells contains Fra-1 and JunB.

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Costimulation of T lymphocytes: the role of CD28, CTLA-4, and B7/BB1 in interleukin-2 production and immunotherapy

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The B7 and CD28 receptor families

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Cloning of B7-2: a CTLA-4 Counter-Receptor That Costimulates Human T Cell Proliferation

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B70 antigen is a second ligand for CTLA-4 and CD28

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Identification of an Alternative CTLA-4 Ligand Costimulatory for T Cell Activation

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Comparative analysis of B7-1 and B7-2 costimulatory ligands: expression and function

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The CD28 ligand B7/BB1 provides costimulatory signal for alloactivation of CD4+ T cells

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Activated human B lymphocytes express three CTLA-4 counterreceptors that costimulate T-cell activation

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Differential T cell costimulatory requirements in CD28-deficient mice

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Regulation of lymphokine messenger RNA stability by a surface-mediated T cell activation pathway

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Regulation of Interleukin-2 Gene Enhancer Activity by the T Cell Accessory Molecule CD28

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The role of the T cell costimulator B7-1 in autoimmunity and the induction and maintenance of tolerance to peripheral antigen

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T-cell antigen CD28 interacts with the lipid kinase phosphatidylinositol 3-kinase by a cytoplasmic Tyr(P)-Met-Xaa-Met motif

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Stimulation of CD28 triggers an association between CD28 and phosphatidylinositol 3-kinase in Jurkat T cells

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CD28 of T lymphocytes associates with phosphatidylinositol 3-kinase

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Two-step TCR zeta/CD3-CD4 and CD28 signaling in T cells: SH2/SH3 domains, protein-tyrosine and lipid kinases

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Binding of phosphatidylinositol-3-OH kinase to CD28 is required for T-cell signalling

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The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1

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Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation

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Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav

1 reference

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Nuclear factor of activated T cells contains Fos and Jun.

1 reference

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p21ras mediates control of IL-2 gene promoter function in T cell activation.

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Contingent genetic regulatory events in T lymphocyte activation

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Association of p21ras with phosphatidylinositol 3-kinase

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7 January 2021

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Phosphatidylinositol-3-OH kinase as a direct target of Ras

1 reference

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10.1002/EJI.1830250428

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