Metabolism. Lysosomal amino acid transporter SLC38A9 signals arginine sufficiency to mTORC1 (Q24313010)

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Language	Label	Description	Also known as
English	Metabolism. Lysosomal amino acid transporter SLC38A9 signals arginine sufficiency to mTORC1	scientific article

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scholarly article

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Metabolism. Lysosomal amino acid transporter SLC38A9 signals arginine sufficiency to mTORC1 (English)

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Solute carrier family 38 member 9

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GOA release 2020-03-11

13

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Bernardo L. Sabatini

17

object named as

Bernardo L Sabatini

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David M. Sabatini

18

object named as

David M Sabatini

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author name string

Shuyu Wang

1

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Zhi-Yang Tsun

2

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Rachel L Wolfson

3

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Kuang Shen

4

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Gregory A Wyant

5

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Molly E Plovanich

6

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Elizabeth D Yuan

7

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Tony D Jones

8

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Lynne Chantranupong

9

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William Comb

10

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Tim Wang

11

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Liron Bar-Peled

12

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Christoph Straub

14

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Choah Kim

15

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Jiwon Park

16

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language of work or name

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publication date

9 January 2015

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347

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6218

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188-94

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A Tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4295826

19 March 2017

Ragulator is a GEF for the rag GTPases that signal amino acid levels to mTORC1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4295826

19 March 2017

mTOR signaling in growth control and disease

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4295826

19 March 2017

mTOR: from growth signal integration to cancer, diabetes and ageing

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4295826

19 March 2017

Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4295826

19 March 2017

The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4295826

19 March 2017

Identification and characterization of a lysosomal transporter for small neutral amino acids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4295826

19 March 2017

Amino acids and mTORC1: from lysosomes to disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4295826

19 March 2017

The Sestrins interact with GATOR2 to negatively regulate the amino-acid-sensing pathway upstream of mTORC1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4295826

19 March 2017

Spatial control of the TSC complex integrates insulin and nutrient regulation of mTORC1 at the lysosome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4295826

19 March 2017

Rapalogs and mTOR inhibitors as anti-aging therapeutics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4295826

19 March 2017

The novel lipid raft adaptor p18 controls endosome dynamics by anchoring the MEK-ERK pathway to late endosomes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4295826

19 March 2017

Localization of Rheb to the endomembrane is critical for its signaling function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4295826

19 March 2017

Sodium-coupled neutral amino acid (System N/A) transporters of the SLC38 gene family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4295826

19 March 2017

Isolation and characterization of human lysosomal membrane glycoproteins, h-lamp-1 and h-lamp-2. Major sialoglycoproteins carrying polylactosaminoglycan

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4295826

19 March 2017

mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H(+)-ATPase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4295826

7 April 2017

Regulation of the mTOR Complex 1 Pathway by Nutrients, Growth Factors, and Stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4295826

7 April 2017

An ATP-competitive mammalian target of rapamycin inhibitor reveals rapamycin-resistant functions of mTORC1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4295826

7 April 2017

Regulation of TORC1 by Rag GTPases in nutrient response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4295826

7 April 2017

Amino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4295826

7 April 2017

Suppression of lysosome function induces autophagy via a feedback down-regulation of MTOR complex 1 (MTORC1) activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4295826

27 September 2017

The folliculin tumor suppressor is a GAP for the RagC/D GTPases that signal amino acid levels to mTORC1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4295826

27 September 2017

Recruitment of folliculin to lysosomes supports the amino acid-dependent activation of Rag GTPases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4295826

27 September 2017

An extended proteome map of the lysosomal membrane reveals novel potential transporters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4295826

27 September 2017

Amino acid signalling upstream of mTOR

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4295826

27 September 2017

Regulation of mTORC1 by the Rag GTPases is necessary for neonatal autophagy and survival.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4295826

27 September 2017

Epidermal growth factor-induced vacuolar (H+)-atpase assembly: a role in signaling via mTORC1 activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4295826

27 September 2017

Rapamycin passes the torch: a new generation of mTOR inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4295826

27 September 2017

mTOR couples cellular nutrient sensing to organismal metabolic homeostasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4295826

27 September 2017

The evolutionary history and tissue mapping of amino acid transporters belonging to solute carrier families SLC32, SLC36, and SLC38.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4295826

27 September 2017

The eukaryotic plasma membrane as a nutrient-sensing device.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4295826

27 September 2017

Rapamycin: clinical results and future opportunities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4295826

27 September 2017

Dynamic aspects of vacuolar and cytosolic amino acid pools of Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4295826

27 September 2017

Novel role of the small GTPase Rheb: its implication in endocytic pathway independent of the activation of mammalian target of rapamycin

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1257132

21 January 2018

Distinct sensor pathways in the hierarchical control of SNAT2, a putative amino acid transceptor, by amino acid availability.

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1257132

21 January 2018

Arginine and Leucine regulate p70 S6 kinase and 4E-BP1 in intestinal epithelial cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4295826

29 November 2018

Lysosomal pool of free-amino acids

1 reference

https://pubmed.ncbi.nlm.nih.gov/25567906

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dietary arginine supplementation increases mTOR signaling activity in skeletal muscle of neonatal pigs

1 reference

https://pubmed.ncbi.nlm.nih.gov/25567906

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1126/SCIENCE.1257132

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

OpenCitations bibliographic resource ID

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Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

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Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

ResearchGate publication ID

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