Prädiktive Wahrnehmungsprozesse: multisensorische Konsequenzen eigener Handlungen

Projekt A3 kombiniert Psychophysik, EEG und fMRT, um handlungsbezogene multisensorische Vorher- sagesprozesse besser zu verstehen. Wir werden kontextuelle Einflüsse und individuelle Unterschiede im Handlungs-Wahrnehmungs-Schaltkreis untersuchen; insbesondere ob aus der Analyse einzelner Handbewegungen abgleitete Mechanismen sich übertragen lassen auf (1) Handlungssequenzen, (2) Fußbewegungen und (3) natürliche Kontexte (z.B. Radfahren). Mit EEG und kombinierter EEG-fMRT werden wir den (4) Zeitverlauf der prädiktiven neuronalen Verarbeitung und (5) individuelle Unterschiede in Personen mit schizotypen Persönlichkeitszügen beleuchten. Und ob (6) gestörte multisensorische Vorhersagen zu einer Beeinträchtigung der Handlungswahrnehmung bei Patienten mit Schizophrenie führen. Unsere Forschung überträgt grundlagenwissenschaftliche Erkenntnisse in den klinischen Kontext um Mechanismen aufzudecken, die Beeinträchtigungen der Handlungsüberwachung unter natürlichen Bedingungen zugrunde liegen.

Neue Projektrelevante Veröffentlichungen

Ody, E., Straube, B., He, Y., & Kircher, T. (2023). Perception of self-generated and externally-generated visual stimuli: Evidence from EEG and behavior. Psychophysiology, 00, e14295. find paper

Belkis Ezgi Arikan, Dimitris Voudouris, Benjamin Straube, and Katja Fiehler (2023). Distinct role of central predictive mechanisms in tactile suppression. Available at SSRN 4622696 find preprint

Kavroulakis, E., van Kemenade, B. M., Arikan, B. E., Kircher, T., & Straube, B. (2022). The effect of self-generated versus externally generated actions on timing, duration, and amplitude of blood oxygen level dependent response for visual feedback processing. Human brain mapping, 43, no. 16 (2022): 4954-4969.. find paper

Kufer, K., Schmitter, C. V., Kircher, T., & Straube, B. (2024). Temporal recalibration in response to delayed visual feedback of active versus passive actions: an fMRI study.Scientific Reports, 14(1), 4632. find paper

Lubinus, C., Einhäuser, W., Schiller, F., Kircher, T., Straube, B.*, & van Kemenade, B. M.* (2022). Action-based predictions affect visual perception, neural processing, and pupil size, regardless of temporal predictability. NeuroImage, 263, 119601. find paper

Ody, E., Kircher, T., Straube, B., & He, Y. (2023). Pre-movement event-related potentials and multivariate pattern of EEG encode action outcome prediction. find paper

Rosenblum, L., Kreß, A., Arikan, B., Straube, B. & Bremmer, F. (2023). Neural correlates of visual and tactile path integration and their task related modulation. Scientific Reports 13, 9913. find paper

Schmitter, C. V., Kufer, K., Steinsträter, O., Sommer, J., Kircher, T., & Straube, B. (2023). Neural correlates of temporal recalibration to delayed auditory feedback of active and passive movements.Human Brain Mapping, 44(17), 6227-6244. find paper

Schmitter, C.V. & Straube, B. (2022). The impact of cerebellar transcranial direct current stimulation (tDCS) on sensorimotor and inter-sensory temporal recalibration. Frontiers in Human Neuroscience, 16, 998843. find paper

Ältere projektrelevante Veröffentlichungen

Acosta, H., Straube, B., & Kircher, T. (2019). Schizotypy and mentalizing: An fMRI study. Neuropsychologia, 124, 299-310. find paper

Arikan , B.E., van Kemenade , B.M., Straube, B., Harris, L.H., & Kircher , T. (2017). Voluntary and Involuntary Movements Widen the Window of Subjective Simultaneity. i-Perception, 8(4), 2041669517719297. find paper

Arikan, B. E., van Kemenade, B. M., Fiehler, K., Kircher, T., Drewing, K., & Straube, B. (2021). Different contributions of efferent and reafferent feedback to sensorimotor temporal recalibration. Scientific Reports, 11(1), 1-15. find paper

Arikan, B. E., van Kemenade, B. M., Podranski, K., Steinsträter, O., Straube, B., & Kircher, T. (2019). Perceiving your hand moving: BOLD suppression in sensory cortices and the role of the cerebellum in the detection of feedback delays. Journal of Vision, 19(14), 4-4. find paper

Backasch, B., Sommer, J., Klöhn-Saghatolislam, F., Müller, M.J., Kircher, T.T., & Leube, D.T. (2014). Dysconnectivity of the inferior frontal gyrus: Implications for an impaired self-other distinction in patients with schizophrenia. Psychiatry Research, 223:202-209. find paper

Bitsch, F., Berger, P., Nagels, A., Falkenberg, I., & Straube, B. (2019). Impaired right temporoparietal junction–hippocampus connectivity in schizophrenia and its relevance for generating representations of other minds. Schizophrenia bulletin, 45(4), 934-945. find paper

Bitsch, F., Berger, P., Nagels, A., Falkenberg, I., & Straube, B. (2021). Characterizing the theory of mind network in schizophrenia reveals a sparser network structure. Schizophrenia Research, 228, 581-589. find paper

Choudhury, M., Steines, M., Nagels, A., Riedl, L., Kircher, T., & Straube, B. (2021). Neural Basis of Speech-Gesture Mismatch Detection in Schizophrenia Spectrum Disorders. Schizophrenia Bulletin. find paper

Cuevas, P., He, Y., Billino, J., Kozasa E. & Straube, B. (2021). Age-related effects on the neural processing of semantic complexity in a continuous narrative: Modulation by gestures already present in young to middle-aged adults. Neuropsychologia, 151:107725. find paper

Cuevas, P., Steines, M., He, Y., Nagels, A., Culham, J., & Straube, B. (2019). The facilitative effect of gestures on the neural processing of semantic complexity in a continuous narrative. NeuroImage, 195, 38-47. find paper

He, Y., Gebhardt, H., Steines, M., Sammer, G., Kircher, T., Nagels, A., & Straube, B. (2015). The EEG and fMRI signatures of neural integration: An investigation of meaningful gestures and corresponding speech. Neuropsychologia, 72, 27-42. find paper

He, Y., Luell, S., Muralikrishnan, R., Straube, B., & Nagels, A. (2020). Gesture's body orientation modulates the N400 for visual sentences primed by gestures. Human brain mapping, 41(17), 4901-4911. find paper

He, Y., Nagels, A., Schlesewsky, M., & Straube, B. (2018). The role of gamma oscillations during integration of metaphoric gestures and abstract speech. Frontiers in psychology, 9, 1348. find paper

He, Y., Steines, M., Sammer, G., Nagels, A., Kircher, T., & Straube, B. (2018). Action-related speech modulates beta oscillations during observation of tool-use gestures. Brain topography, 31(5), 838-847. find paper

He, Y., Steines, M., Sammer, G., Nagels, A., Kircher, T., & Straube, B. (2021). Modality-specific dysfunctional neural processing of social-abstract and non-social-concrete information in schizophrenia. NeuroImage: Clinical, 29, 102568. find paper

He, Y., Steines, M., Sommer, J., Gebhardt, H., Nagels, A., Sammer, G., Kircher, T., Straube, B. (2018). Spatial - temporal dynamics of gesture - speech integration: a simultaneous EEG-fMRI study. Brain Structure and Function, 223(7), 3073-3089. find paper

Kavroulakis, E., van Kemenade, B. M., Arikan, B. E., Kircher, T., & Straube, B. (2021). The effect of self-vs. externally generated actions on timing, duration and amplitude of BOLD response for visual feedback processing. bioRxiv. find preprint

Krala, M., van Kemenade, B., Straube, B., Kircher, T., & Bremmer, F. (2019). Predictive coding in a multisensory path integration task: An fMRI study. Journal of Vision, 19(11), 13-13. find paper

Lubinus, C., Einhaeuser, W., Schiller, F., Kircher, T., Straube, B., & van Kemenade, B. M. (2021). Action-based predictions affect visual perception, neural processing, and pupil size, regardless of temporal predictability. bioRxiv. find preprint

Nagels, A., Kircher, T., Grosvald, M., Steines, M., & Straube, B. (2019). Evidence for gesture-speech mismatch detection impairments in schizophrenia. Psychiatry research, 273, 15-21. find paper

Nagels, A., Kircher, T., Steines, M., Grosvald, M., & Straube, B. (2015). A brief self-rating scale for the assessment of individual differences in gesture perception and production. Learning and Individual Differences, 39, 73–80. find paper

Pazen, M., Uhlmann, L., van Kemenade, B. M., Steinsträter, O., Straube, B., & Kircher, T. (2020). Predictive perception of self-generated movements: Commonalities and differences in the neural processing of tool and hand actions. NeuroImage, 206, 116309. find paper

Riedl, L., Nagels, A., Sammer, G., & Straube, B. (2020). A multimodal speech-gesture training intervention for patients with schizophrenia and its neural underpinnings–the study protocol of a randomized controlled pilot trial. Frontiers in psychiatry, 11, 110. find paper

Schmalenbach, S.B., Billino, J., Kircher, T., van Kemenade, B.M., & Straube, B. (2017). Links between gestures and multisensory processing: individual differences suggest a compensation mechanism. Frontiers in Psychology, 8:1828 find paper

Schmitter, C., Steinsträter, O., Kircher, T., van Kemenade, B. M., & Straube, B. (2021). Commonalities and differences in predictive neural processing of discrete vs continuous action feedback. NeuroImage, 229, 117745. find paper

Schuelke, R., & Straube, B. (2017). Modulating the assessment of semantic speech–gesture relatedness via transcranial direct current stimulation of the left frontal cortex. Brain Stimulation, 10(2), 223–230. find paper

Schülke, R., & Straube, B. (2019). Transcranial direct current stimulation improves semantic speech–gesture matching in patients with schizophrenia spectrum disorder. Schizophrenia bulletin, 45(3), 522-530. find paper

Steines, M., Nagels, A., Kircher, T., & Straube, B. 2 (2021). The role of the left and right inferior frontal gyrus in processing metaphoric and unrelated co-speech gestures. NeuroImage, 237, 118182. find paper

Straube, B., Green, A., Sass, K., & Kircher, T. (2014). Superior Temporal Sulcus Disconnectivity During Processing of Metaphoric Gestures in Schizophrenia. Schizophrenia Bulletin, 40(4), 936-944. find paper

Straube, B., Green, A., Weis, S., & Kircher, T. (2012). A Supramodal Neural Network for Speech and Gesture Semantics: An fMRI Study. PLoS ONE, 7(11), e51207. find paper

Straube, B., He, Y., Steines, M., Gebhardt, H., Kircher, T., Sammer, G., & Nagels, A. (2013). Supramodal neural processing of abstract information conveyed by speech and gesture. Frontiers in Behavioral Neuroscience, 7, 120. find paper

Straube, B., van Kemenade, B. M., Arikan, B. E., Fiehler, K., Harris, L. R., Leube, D., & Kircher, T. (2017). Predicting the multisensory consequences of one's own action: BOLD suppression in auditory and visual cortices. PLOS ONE, 12(1), e0169131. find paper

Straube, B., van Kemenade, B.M., Kircher, T. & Schülke, R. (2020). Transcranial Direct Current Stimulation Improves Action-Outcome Monitoring in Schizophrenia Spectrum Disorder. Brain Communications, 2(2), fcaa151. find paper

Uhlmann, L., Pazen, M., van Kemenade, B. M., Steisträter, O., Harris, L.R., Kircher, T. & Straube, B (2020). Seeing your own or someone else's hand moving in accordance with your action: The neural interaction of agency and hand identity. Human Brain Mapping, 41, 2474-2489. find paper

Uhlmann, L., Pazen, M., van Kemenade, B.M., Kircher, T. & Straube, B. (2021). Neural correlates of self-other distinction in patients with schizophrenia spectrum disorders: The roles of agency and hand identity. Schizophrenia Bulletin, 47(5), 1399-1408. find paper

Van Kemenade, B. M., Kircher, T., Arikan, B. E., & Straube, B. (2016). Predicting the sensory consequences of one’s own action: First evidence for multisensory facilitation. Attention, Perception, & Psychophysics, 78(8), 2515-2526. find paper

van Kemenade, B.M., Arikan, B.E., Kircher, T., & Straube, B. (2017). The angular gyrus is a supramodal comparator area in action-outcome monitoring. Brain Structure and Function, 222(8), 3691-3703. find paper

Van Kemenade, B.M., Arikan, B.E., Podranski, K., Steinsträter, O., Kircher, T., & Straube, B. (2019). Distinct roles for the cerebellum, angular gyrus and middle temporal gyrus in action-feedback monitoring. Cerebral Cortex, 29(4), 1520-1531. find paper

Wende, K. C., Nagels, A., Stratmann, M., Chatterjee, A., Kircher, T., & Straube, B. (2015). Neural basis of altered physical and social causality judgements in schizophrenia. Schizophrenia Research, 161(2–3), 244–251. find paper

Wroblewski, A., He, Y., & Straube, B. (2020). Dynamic Causal Modelling suggests impaired effective connectivity in patients with schizophrenia spectrum disorders during gesture-speech integration. Schizophrenia research, 216, 175-183. find paper