A consensus statement outlines the best practices to refine animal welfare in rodent models of cancer. Their adoption will allow the standardization of experimental interventions, considering the characteristics of each cancer model, thereby improving the reproducibility and translational value of data obtained in rodents.
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Ritter, A.C., Cheleuitte-Nieves, C. & Lipman, N.S. The OBSERVE guidelines provide refinement criteria for rodent oncology models. Nat Protoc 19, 2831–2832 (2024). https://doi.org/10.1038/s41596-024-01008-9
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DOI: https://doi.org/10.1038/s41596-024-01008-9