About: PPADS

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

PPADS (pyridoxalphosphate-6-azophenyl-2',4'-disulfonic acid) is a selective purinergic P2X antagonist. It is able to block contractions of rabbit vas deferens induced by ATP or α,β,methylene-ATP. It appears to be relatively selective for P2X receptors, having no appreciable activity at α1 adrenergic, muscarinic M2 and M3, histamine H1, and adenosine A1 receptors.

Property	Value
dbo:abstract	PPADS (pyridoxalphosphate-6-azophenyl-2',4'-disulfonic acid) is a selective purinergic P2X antagonist. It is able to block contractions of rabbit vas deferens induced by ATP or α,β,methylene-ATP. It appears to be relatively selective for P2X receptors, having no appreciable activity at α1 adrenergic, muscarinic M2 and M3, histamine H1, and adenosine A1 receptors. (en)
dbo:alternativeName	PPADS (en)
dbo:iupacName	4-[(E)-{4-formyl-5-hydroxy-6-methyl-3-[(phosphonooxy)methyl]pyridin-2-yl}diazenyl]benzene-1,3-disulfonic acid (en)
dbo:thumbnail	wiki-commons:Special:FilePath/PPADS.svg?width=300
dbo:wikiPageID	32521721 (xsd:integer)
dbo:wikiPageLength	2740 (xsd:nonNegativeInteger)
dbo:wikiPageRevisionID	1077171271 (xsd:integer)
dbo:wikiPageWikiLink	dbr:Antagonist dbc:Azo_compounds dbc:Organophosphates dbc:Sulfonic_acids dbr:Muscarinic_acetylcholine_receptor_M2 dbr:Muscarinic_acetylcholine_receptor_M3 dbr:Adenosine_A1_receptor dbr:Adenosine_triphosphate dbr:Alpha-1_adrenergic_receptor dbr:Histamine_H1_receptor dbc:Pyridines dbr:P2X_receptor
dbp:imagefile	PPADS.svg (en)
dbp:imagesize	200 (xsd:integer)
dbp:iupacname	4 (xsd:integer)
dbp:othernames	PPADS (en)
dbp:wikiPageUsesTemplate	dbt:Chembox dbt:Chembox_Hazards dbt:Chembox_Identifiers dbt:Chembox_Properties dbt:Genito-urinary-drug-stub dbt:Reflist dbt:Cascite dbt:Ebicite dbt:Fdacite dbt:Purinergics
dct:subject	dbc:Azo_compounds dbc:Organophosphates dbc:Sulfonic_acids dbc:Pyridines
gold:hypernym	dbr:Antagonist
rdf:type	owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q11173 yago:WikicatAzoCompounds yago:WikicatOrganophosphates yago:WikicatSulfonicAcids yago:Abstraction100002137 yago:Acid114607521 yago:Base114618253 yago:Chemical114806838 yago:Cognition100023271 yago:Compound105870180 yago:Compound114818238 yago:Concept105835747 yago:Content105809192 yago:Idea105833840 yago:Insecticide114919948 yago:Material114580897 yago:Matter100020827 yago:Organophosphate114969994 yago:Part113809207 yago:Pesticide114980215 yago:PhysicalEntity100001930 yago:PsychologicalFeature100023100 yago:Pyridine114692510 yago:Relation100031921 dbo:ChemicalCompound dbo:Drug yago:Substance100019613 yago:SulfonicAcid114616508 yago:Whole105869584 yago:WikicatPyridines
rdfs:comment	PPADS (pyridoxalphosphate-6-azophenyl-2',4'-disulfonic acid) is a selective purinergic P2X antagonist. It is able to block contractions of rabbit vas deferens induced by ATP or α,β,methylene-ATP. It appears to be relatively selective for P2X receptors, having no appreciable activity at α1 adrenergic, muscarinic M2 and M3, histamine H1, and adenosine A1 receptors. (en)
rdfs:label	PPADS (en)
owl:sameAs	freebase:PPADS yago-res:PPADS wikidata:PPADS dbpedia-sh:PPADS dbpedia-sr:PPADS https://global.dbpedia.org/id/4srps
prov:wasDerivedFrom	wikipedia-en:PPADS?oldid=1077171271&ns=0
foaf:depiction	wiki-commons:Special:FilePath/PPADS.svg
foaf:isPrimaryTopicOf	wikipedia-en:PPADS
is dbo:wikiPageRedirects of	dbr:Pyridoxalphosphate-6-azophenyl-2',4'-disulfonic_acid
is dbo:wikiPageWikiLink of	dbr:Rostral_ventromedial_medulla dbr:P2RX4 dbr:P2RX7 dbr:P2X_purinoreceptor dbr:Pyridoxalphosphate-6-azophenyl-2',4'-disulfonic_acid
is foaf:primaryTopic of	wikipedia-en:PPADS