[go: up one dir, main page]

About: NhaD family

An Entity of Type: Thing, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

The NhaD family (TC# 2.A.62) belongs to the Ion Transporter (IT) Superfamily. A representative list of proteins belonging to the NhaD family can be found in the Transporter Classification Database. The NhaD Na+/H+ antiporter has been characterized from two Vibrio species: V. parahaemolyticus and V. cholerae and in the haloalkaliphile, . These proteins and their homologues are 400-500 aas long and exhibit 10-13 TMSs. They catalyze Na+/H+ and Li+/H+ antiport. They exhibit activity at basic pH (8-10) with no activity at pH 7.5. The Amylolytica antiporter has low Na+ affinity and has optimal activity at 600 mM Na+. Homologues are found in Pseudomonadota of all groups, Flavobacteriia, and Chlamydia. Distant homologues of the IT superfamily are ubiquitous.

Property Value
dbo:abstract
  • The NhaD family (TC# 2.A.62) belongs to the Ion Transporter (IT) Superfamily. A representative list of proteins belonging to the NhaD family can be found in the Transporter Classification Database. The NhaD Na+/H+ antiporter has been characterized from two Vibrio species: V. parahaemolyticus and V. cholerae and in the haloalkaliphile, . These proteins and their homologues are 400-500 aas long and exhibit 10-13 TMSs. They catalyze Na+/H+ and Li+/H+ antiport. They exhibit activity at basic pH (8-10) with no activity at pH 7.5. The Amylolytica antiporter has low Na+ affinity and has optimal activity at 600 mM Na+. Homologues are found in Pseudomonadota of all groups, Flavobacteriia, and Chlamydia. Distant homologues of the IT superfamily are ubiquitous. The generalized reaction catalyzed by NhaD is: nH+ (in) + mNa+ (out) ⇌ nH+ (out) + mNa+ (in). (en)
dbo:wikiPageExternalLink
dbo:wikiPageID
  • 49781600 (xsd:integer)
dbo:wikiPageLength
  • 6196 (xsd:nonNegativeInteger)
dbo:wikiPageRevisionID
  • 1084703448 (xsd:integer)
dbo:wikiPageWikiLink
dbp:revision
  • 699838558 (xsd:integer)
dbp:sourcepath
  • http://www.tcdb.org/search/result.php?tc=2.A.62|sourcearticle=2.A.62 The NhaD Na+:H+ Antiporter Family (en)
dbp:wikiPageUsesTemplate
dcterms:subject
rdfs:comment
  • The NhaD family (TC# 2.A.62) belongs to the Ion Transporter (IT) Superfamily. A representative list of proteins belonging to the NhaD family can be found in the Transporter Classification Database. The NhaD Na+/H+ antiporter has been characterized from two Vibrio species: V. parahaemolyticus and V. cholerae and in the haloalkaliphile, . These proteins and their homologues are 400-500 aas long and exhibit 10-13 TMSs. They catalyze Na+/H+ and Li+/H+ antiport. They exhibit activity at basic pH (8-10) with no activity at pH 7.5. The Amylolytica antiporter has low Na+ affinity and has optimal activity at 600 mM Na+. Homologues are found in Pseudomonadota of all groups, Flavobacteriia, and Chlamydia. Distant homologues of the IT superfamily are ubiquitous. (en)
rdfs:label
  • NhaD family (en)
owl:sameAs
prov:wasDerivedFrom
foaf:isPrimaryTopicOf
is dbo:wikiPageWikiLink of
is foaf:primaryTopic of
Powered by OpenLink Virtuoso    This material is Open Knowledge     W3C Semantic Web Technology     This material is Open Knowledge    Valid XHTML + RDFa
This content was extracted from Wikipedia and is licensed under the Creative Commons Attribution-ShareAlike 3.0 Unported License