Propranolol

This article relies largely or entirely on a single source. Please help improve this article by introducing appropriate citations of additional sources.

Propanolol (brand names Bedranol, Beta-prograne, Half Beta-prograne) belongs to a group of medicines called beta blockers. It is used to treat heart problems, help with some of the symptoms of anxiety and prevent migraines.^[1]

For heart problems, propranolol can be taken to to:^[1]

• treat high blood pressure
• treat conditions that cause an irregular heartbeat (arrhythmia), like atrial fibrillation
• help prevent future heart disease, heart attacks and stroke
• help prevent chest pain caused by angina

Propranolol

Clinical data
Pronunciation	/proʊˈprænəˌlɑːl/
Trade names	Inderal, others
AHFS/Drugs.com	Monograph
License data	US DailyMed: Propranolol
Pregnancy category	AU: C
Routes of administration	Oral, rectal, intravenous
ATC code	C07AA05 (WHO)
Pharmacokinetic data
Bioavailability	26%
Protein binding	90%
Metabolism	Liver (extensive) CYP1A2, CYP2D6; minor: CYP2C19, CYP3A4
Metabolites	N-desisopropylpropranolol, 4'-hydroxypropanolol
Elimination half-life	4–5 hours
Excretion	Kidney (<1%)
Identifiers
CAS Number	525-66-6 Y
PubChem CID	4946
IUPHAR/BPS	564
DrugBank	DB00571 Y
ChemSpider	4777 Y
UNII	9Y8NXQ24VQ
KEGG	D08443 Y as HCl: D00483 Y
ChEBI	CHEBI:8499 Y
ChEMBL	ChEMBL27 Y
ECHA InfoCard	100.007.618
Chemical and physical data
Chirality	Racemic mixture
(verify)