Ribonukleaza P
| Ribonukleaza P | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| |||||||||
| Identifikatori | |||||||||
| EC broj | 3.1.26.5 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Ribonukleaza P (EC 3.1.26.5, RNaza P) je enzim.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Endonukleolitičko razlaganje RNK, uklanjanje 5'-ekstranukleotida sa tRNK prekursora
Ovaj enzim sadrži RNK. On je esencijalan za tRNK obradu.
Reference
- ↑ Bikoff, E.K. and Gefter, M.L. (1975). „In vitro synthesis of transfer RNA. I. Purification of required components”. J. Biol. Chem. 250: 6240-6247. PMID 1099089.
- ↑ Bikoff, E.K., La Rue, B.F. and Gefter, M.L. (1975). „In vitro synthesis of transfer RNA. II. Identification of required enzymatic activities”. J. Biol. Chem. 250: 6248-6255. PMID 1099090.
- ↑ Robertson, H.D., Altman, S. and Smith, J.D. (1972). „Purification and properties of a specific Escherichia coli ribonuclease which cleaves a tyrosine transfer ribonucleic acid presursor”. J. Biol. Chem. 247: 5243-5251. PMID 4560501.
Literatura
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.