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In vivo 31P NMR measurement of glucose-6-phosphate in the rat muscle after exercise

Magn Reson Med. 1993 Sep;30(3):347-50. doi: 10.1002/mrm.1910300311.

Abstract

Comparison of 31P NMR spectra of the rat gastrocnemius, obtained in vivo and from PCA extracts, after electrically induced contractions, demonstrates that glucose-6-phosphate (G6P) is the major metabolite in the low-field part of the PME spectral region. In vivo 31P NMR can thus be used to measure the muscle G6P concentration after exercise.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Electric Stimulation
  • Glucose-6-Phosphate
  • Glucosephosphates / analysis*
  • Isometric Contraction / physiology*
  • Magnetic Resonance Spectroscopy*
  • Male
  • Muscles / chemistry
  • Muscles / metabolism*
  • Physical Exertion / physiology
  • Rats
  • Rats, Sprague-Dawley

Substances

  • Glucosephosphates
  • Glucose-6-Phosphate