(Q38732773)

5 September 2017

title

Hedgehog receptor function during craniofacial development (English)

1 reference

5 September 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26875496%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26875496%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26875496%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Guilherme M Xavier

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26875496%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Anahid A Birjandi

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26875496%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Finn Geoghegan

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26875496%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

language of work or name

English

0 references

publication date

11 February 2016

1 reference

5 September 2017

published in

Developmental Biology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26875496%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

volume

415

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26875496%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

issue

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26875496%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

page(s)

198-215

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26875496%20AND%20SRC:MED&resulttype=core&format=json

Context-dependent signal integration by the GLI code: the oncogenic load, pathways, modifiers and implications for cancer therapy

13 June 2020

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Mouse Dispatched homolog1 is required for long-range, but not juxtacrine, Hh signaling

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The cellular and molecular etiology of the craniofacial defects in the avian ciliopathic mutant talpid2.

7 January 2021

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Activity-dependent internalization of smoothened mediated by beta-arrestin 2 and GRK2

7 January 2021

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Dual roles for patched in sequestering and transducing Hedgehog

7 January 2021

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Sonic Hedgehog dependent phosphorylation by CK1α and GRK2 is required for ciliary accumulation and activation of smoothened

7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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Signaling by SHH rescues facial defects following blockade in the brain.

7 January 2021

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7 January 2021

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7 January 2021

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Hedgehog signalling in development of the secondary palate

7 January 2021

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Sonic hedgehog signalling inhibits palatogenesis and arrests tooth development in a mouse model of the nevoid basal cell carcinoma syndrome

7 January 2021

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Microform holoprosencephaly in mice that lack the Ig superfamily member Cdon.

7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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Mutations in Hedgehog acyltransferase (Hhat) perturb Hedgehog signaling, resulting in severe acrania-holoprosencephaly-agnathia craniofacial defects

7 January 2021

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Mouse suppressor of fused is a negative regulator of sonic hedgehog signaling and alters the subcellular distribution of Gli1

7 January 2021

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A Smoothened-Evc2 complex transduces the Hedgehog signal at primary cilia

7 January 2021

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7 January 2021

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Early Hedgehog signaling from neural to oral epithelium organizes anterior craniofacial development

7 January 2021

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7 January 2021

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7 January 2021

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The Ptch1(DL) mouse: a new model to study lambdoid craniosynostosis and basal cell nevus syndrome-associated skeletal defects

7 January 2021

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Small-molecule inhibitors of the AAA+ ATPase motor cytoplasmic dynein

7 January 2021

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Desensitization of G protein-coupled receptors and neuronal functions

7 January 2021

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A new gene, EVC2, is mutated in Ellis-van Creveld syndrome

7 January 2021

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G protein-coupled receptor-promoted trafficking of Gbeta1gamma2 leads to AKT activation at endosomes via a mechanism mediated by Gbeta1gamma2-Rab11a interaction

7 January 2021

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Pathogenesis of holoprosencephaly

7 January 2021

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Altered Neural Cell Fates and Medulloblastoma in Mouse patched Mutants

7 January 2021

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Overexpression of ptc1 inhibits induction of Shh target genes and prevents normal patterning in the neural tube

7 January 2021

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Conservation of the hedgehog/patched signaling pathway from flies to mice: induction of a mouse patched gene by Hedgehog

7 January 2021

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Cloning, mapping, and expression analysis of a gene encoding a novel mammalian EGF-related protein (SCUBE1).

7 January 2021

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The whereabouts of a morphogen: direct evidence for short- and graded long-range activity of hedgehog signaling peptides

7 January 2021

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Shh signaling within the dental epithelium is necessary for cell proliferation, growth and polarization

7 January 2021

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Pituitary stalk interruption syndrome: Case report of three cases with review of literature

7 January 2021

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Rhabdomyosarcomas and radiation hypersensitivity in a mouse model of Gorlin syndrome

7 January 2021

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A mammalian patched homolog is expressed in target tissues of sonic hedgehog and maps to a region associated with developmental abnormalities

7 January 2021

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Sonic hedgehog in the pharyngeal endoderm controls arch pattern via regulation of Fgf8 in head ectoderm

7 January 2021

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Expression of the Scube3 epidermal growth factor-related gene during early embryonic development in the mouse.

7 January 2021

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Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function

7 January 2021

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The kinesin-4 protein Kif7 regulates mammalian Hedgehog signalling by organizing the cilium tip compartment

7 January 2021

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Sonic hedgehogParticipates in Craniofacial Morphogenesis and Is Down-regulated by Teratogenic Doses of Retinoic Acid

7 January 2021

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Definition of critical periods for Hedgehog pathway antagonist-induced holoprosencephaly, cleft lip, and cleft palate

7 January 2021

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Scube2 mediates Hedgehog signalling in the zebrafish embryo

7 January 2021

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Essential role for ligand-dependent feedback antagonism of vertebrate hedgehog signaling by PTCH1, PTCH2 and HHIP1 during neural patterning

7 January 2021

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Cdon mutation and fetal ethanol exposure synergize to produce midline signaling defects and holoprosencephaly spectrum disorders in mice

7 January 2021

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Rescue of holoprosencephaly in fetal alcohol-exposed Cdon mutant mice by reduced gene dosage of Ptch1.

7 January 2021

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Unique organization of the frontonasal ectodermal zone in birds and mammals.

7 January 2021

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A SHH-responsive signaling center in the forebrain regulates craniofacial morphogenesis via the facial ectoderm

7 January 2021

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A zone of frontonasal ectoderm regulates patterning and growth in the face.

7 January 2021

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A dynamic Shh expression pattern, regulated by SHH and BMP signaling, coordinates fusion of primordia in the amniote face

7 January 2021

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Cilia and Hedgehog responsiveness in the mouse

7 January 2021

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Gli proteins in development and disease

7 January 2021

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The output of Hedgehog signaling is controlled by the dynamic association between Suppressor of Fused and the Gli proteins

7 January 2021

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G-protein-coupled receptors and localized signaling in the primary cilium during ventral neural tube patterning

7 January 2021

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Receptor-mediated endocytosis of soluble and membrane-tethered Sonic hedgehog by Patched-1

7 January 2021

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Hedgehog signaling in animal development: paradigms and principles

7 January 2021

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Boc and Gas1 each form distinct Shh receptor complexes with Ptch1 and are required for Shh-mediated cell proliferation

7 January 2021

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Hedgehog signaling in the neural crest cells regulates the patterning and growth of facial primordia

7 January 2021

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Scube activity is necessary for Hedgehog signal transduction in vivo

7 January 2021

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BOC, an Ig superfamily member, associates with CDO to positively regulate myogenic differentiation

7 January 2021

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GLI3 frameshift mutations cause autosomal dominant Pallister-Hall syndrome

7 January 2021

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Mutations in LRP2, which encodes the multiligand receptor megalin, cause Donnai-Barrow and facio-oculo-acoustico-renal syndromes

7 January 2021

1 reference

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The zebrafish-secreted matrix protein you/scube2 is implicated in long-range regulation of hedgehog signaling.

7 January 2021

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Mouse dispatched mutants fail to distribute hedgehog proteins and are defective in hedgehog signaling

7 January 2021

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The teratogenic effects of prenatal ethanol exposure are exacerbated by Sonic Hedgehog or GLI2 haploinsufficiency in the mouse.

7 January 2021

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Gli2 trafficking links Hedgehog-dependent activation of Smoothened in the primary cilium to transcriptional activation in the nucleus

7 January 2021

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The role of ciliary trafficking in Hedgehog receptor signaling

7 January 2021

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Radiological features in 82 patients with nevoid basal cell carcinoma (NBCC or Gorlin) syndrome

7 January 2021

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Clinical and radiological features in young individuals with nevoid basal cell carcinoma syndrome

7 January 2021

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Clinical manifestations in 105 persons with nevoid basal cell carcinoma syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Mammalian suppressor-of-fused modulates nuclear-cytoplasmic shuttling of Gli-1

7 January 2021

1 reference

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The Roles of Hedgehog Signaling in Upper Lip Formation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Disrupting hedgehog and WNT signaling interactions promotes cleft lip pathogenesis

7 January 2021

1 reference

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Sonic hedgehog signaling regulates reciprocal epithelial-mesenchymal interactions controlling palatal outgrowth

7 January 2021

1 reference

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Evidence that the WNT-inducible growth arrest-specific gene 1 encodes an antagonist of sonic hedgehog signaling in the somite

7 January 2021

1 reference

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Transdifferentiation of the ventral retinal pigmented epithelium to neural retina in the growth arrest specific gene 1 mutant

7 January 2021

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7 January 2021

1 reference

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Follow-up association studies of chromosome region 9q and nonsyndromic cleft lip/palate.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Fetal alcohol exposure impairs Hedgehog cholesterol modification and signaling.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Mouse Kif7/Costal2 is a cilia-associated protein that regulates Sonic hedgehog signaling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

The inductive role of Wnt-β-Catenin signaling in the formation of oral apparatus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Regulation of Sufu activity by p66β and Mycbp provides new insight into vertebrate Hedgehog signaling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Disruption of Scube2 Impairs Endochondral Bone Formation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

The decoupling of Smoothened from Galphai proteins has little effect on Gli3 protein processing and Hedgehog-regulated chick neural tube patterning

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Hedgehog-mediated patterning of the mammalian embryo requires transporter-like function of dispatched

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

A spontaneous mouse mutation, mesenchymal dysplasia (mes), is caused by a deletion of the most C-terminal cytoplasmic domain of patched (ptc)

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Contributions of PTCH gene variants to isolated cleft lip and palate

7 January 2021

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Molecular interactions coordinating the development of the forebrain and face.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Mechanisms that underlie co-variation of the brain and face

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Gas1 extends the range of Hedgehog action by facilitating its signaling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

The orphan G protein-coupled receptor, Gpr161, encodes the vacuolated lens locus and controls neurulation and lens development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

The mode of Hedgehog binding to Ihog homologues is not conserved across different phyla

7 January 2021

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Smoothened signal transduction is promoted by G protein-coupled receptor kinase 2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Patched1 is required in neural crest cells for the prevention of orofacial clefts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Multiple hits during early embryonic development: digenic diseases and holoprosencephaly

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Human developmental disorders and the Sonic hedgehog pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Mutations in PATCHED-1, the receptor for SONIC HEDGEHOG, are associated with holoprosencephaly

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Ptch2, a second mouse Patched gene is co-expressed with Sonic hedgehog

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

G-protein-coupled receptors, Hedgehog signaling and primary cilia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

The ciliary G-protein-coupled receptor Gpr161 negatively regulates the Sonic hedgehog pathway via cAMP signaling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Evc regulates a symmetrical response to Shh signaling in molar development.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

The mutational spectrum of the sonic hedgehog gene in holoprosencephaly: SHH mutations cause a significant proportion of autosomal dominant holoprosencephaly.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Oxysterol binding to the extracellular domain of Smoothened in Hedgehog signaling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Mice with a targeted mutation of patched2 are viable but develop alopecia and epidermal hyperplasia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Gli protein activity is controlled by multisite phosphorylation in vertebrate Hedgehog signaling.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Intraflagellar transport, cilia, and mammalian Hedgehog signaling: analysis in mouse embryonic fibroblasts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Complex interactions between genes controlling trafficking in primary cilia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Boc is a receptor for sonic hedgehog in the guidance of commissural axons

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Hair cycle regulation of Hedgehog signal reception

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Phosphorylation of Gli2 by protein kinase A is required for Gli2 processing and degradation and the Sonic Hedgehog-regulated mouse development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Patterning of palatal rugae through sequential addition reveals an anterior/posterior boundary in palatal development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Vertebrate homologs of Drosophila suppressor of fused interact with the gli family of transcriptional regulators

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Intraflagellar transport (IFT) role in ciliary assembly, resorption and signalling.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Identification of a palmitic acid-modified form of human Sonic hedgehog

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Roles for Hedgehog signaling in adult organ homeostasis and repair

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Holoprosencephaly: signaling interactions between the brain and the face, the environment and the genes, and the phenotypic variability in animal models and humans

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

The product of hedgehog autoproteolytic cleavage active in local and long-range signalling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Cdon promotes neural crest migration by regulating N-cadherin localization

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

EFCAB7 and IQCE regulate hedgehog signaling by tethering the EVC-EVC2 complex to the base of primary cilia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Holoprosencephaly and holoprosencephaly-like phenotype and GAS1 DNA sequence changes: Report of four Brazilian patients

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Disruption of Fgf10/Fgfr2b-coordinated epithelial-mesenchymal interactions causes cleft palate

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Mutations in the human Sonic Hedgehog gene cause holoprosencephaly

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Truncating loss-of-function mutations of DISP1 contribute to holoprosencephaly-like microform features in humans

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Loss-of-function mutations in the human GLI2 gene are associated with pituitary anomalies and holoprosencephaly-like features

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Patched1 regulates hedgehog signaling at the primary cilium

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Hedgehog signal transduction by Smoothened: pharmacologic evidence for a 2-step activation process

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Clinical characterization of individuals with deletions of genes in holoprosencephaly pathways by aCGH refines the phenotypic spectrum of HPE.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Patterning of the embryonic forebrain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Catching a Gli-mpse of Hedgehog

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

The Gli code: an information nexus regulating cell fate, stemness and cancer.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Ellis-van Creveld syndrome and Weyers acrodental dysostosis are caused by cilia-mediated diminished response to hedgehog ligands

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Evc is a positive mediator of Ihh-regulated bone growth that localises at the base of chondrocyte cilia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Mutations in two nonhomologous genes in a head-to-head configuration cause Ellis-van Creveld syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Mutations in a new gene in Ellis-van Creveld syndrome and Weyers acrodental dysostosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Complete cloning and sequencing of rat gp330/"megalin," a distinctive member of the low density lipoprotein receptor gene family

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Cdon and Boc: Two transmembrane proteins implicated in cell-cell communication.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Shh/Boc signaling is required for sustained generation of ipsilateral projecting ganglion cells in the mouse retina.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

A phenotype-driven ENU mutagenesis screen identifies novel alleles with functional roles in early mouse craniofacial development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Specialized filopodia direct long-range transport of SHH during vertebrate tissue patterning

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Nevoid basal cell carcinoma syndrome with cleft lip and palate associated with the novel PTCH gene mutations

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Zebrafish con/disp1 reveals multiple spatiotemporal requirements for Hedgehog-signaling in craniofacial development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Gas1 is a pleiotropic regulator of cellular functions: from embryonic development to molecular actions in cancer gene therapy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Boc modifies the spectrum of holoprosencephaly in the absence of Gas1 function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Gas1 is a modifier for holoprosencephaly and genetically interacts with sonic hedgehog

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

LRP2/megalin is required for patterning of the ventral telencephalon

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

A GLI1-p53 inhibitory loop controls neural stem cell and tumour cell numbers

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Melanomas require HEDGEHOG-GLI signaling regulated by interactions between GLI1 and the RAS-MEK/AKT pathways.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Hh signaling regulates patterning and morphogenesis of the pharyngeal arch-derived skeleton

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Hedgehog activity controls opening of the primary mouth

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Fuz mutant mice reveal shared mechanisms between ciliopathies and FGF-related syndromes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Patched acts catalytically to suppress the activity of Smoothened

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

It's all in your head: new insights into craniofacial development and deformation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

The cell surface membrane proteins Cdo and Boc are components and targets of the Hedgehog signaling pathway and feedback network in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Facial clefting in Tp63 deficient mice results from altered Bmp4, Fgf8 and Shh signaling.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Mouse Disp1 is required in sonic hedgehog-expressing cells for paracrine activity of the cholesterol-modified ligand

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

A mechanism for vertebrate Hedgehog signaling: recruitment to cilia and dissociation of SuFu–Gli protein complexes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Dispatched and scube mediate the efficient secretion of the cholesterol-modified hedgehog ligand

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Protein kinase A acts at the basal body of the primary cilium to prevent Gli2 activation and ventralization of the mouse neural tube

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Hedgehog signaling is required for cranial neural crest morphogenesis and chondrogenesis at the midline in the zebrafish skull.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Structure of the human smoothened receptor bound to an antitumour agent

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Sonic hedgehog is required for cardiac outflow tract and neural crest cell development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Signaling integration in the rugae growth zone directs sequential SHH signaling center formation during the rostral outgrowth of the palate

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Kinetics of hedgehog-dependent full-length Gli3 accumulation in primary cilia and subsequent degradation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Defective forebrain development in mice lacking gp330/megalin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Closure of the posterior neuropore in the vl mutant mouse

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

The you gene encodes an EGF-CUB protein essential for Hedgehog signaling in zebrafish

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

A novel secreted, cell-surface glycoprotein containing multiple epidermal growth factor-like repeats and one CUB domain is highly expressed in primary osteoblasts and bones

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

SCUBE3 is an endogenous TGF-β receptor ligand and regulates the epithelial-mesenchymal transition in lung cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Scube1 is expressed during facial development in the mouse

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Scube3 is expressed in multiple tissues during development but is dispensable for embryonic survival in the mouse

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Sonic hedgehog is essential for first pharyngeal arch development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Smoothened transduces Hedgehog signal by forming a complex with Evc/Evc2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Identification of a novel family of cell-surface proteins expressed in human vascular endothelium

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Quantitative analyses link modulation of sonic hedgehog signaling to continuous variation in facial growth and shape

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Cdo functions at multiple points in the Sonic Hedgehog pathway, and Cdo-deficient mice accurately model human holoprosencephaly

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Bocmodifies the holoprosencephaly spectrum ofCdomutant mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Ocular abnormalities in mice lacking the immunoglobulin superfamily member Cdo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Smoothened mutants reveal redundant roles for Shh and Ihh signaling including regulation of L/R symmetry by the mouse node

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009

Pathogenesis of neural dysraphism in the mouse mutant vacuolated lens (vl).

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2016.02.009