Address
:
[go:
up one dir
,
main page
]
Include Form
Remove Scripts
Accept Cookies
Show Images
Show Referer
Rotate13
Base64
Strip Meta
Strip Title
Session Cookies
Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q37109670)
Watch
English
A GLI1-p53 inhibitory loop controls neural stem cell and tumour cell numbers
scientific article published on 12 February 2009
In more languages
default for all languages
No label defined
No description defined
edit
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
2647769
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19214186%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 January 2020
title
A GLI1-p53 inhibitory loop controls neural stem cell and tumour cell numbers
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
2647769
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19214186%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 January 2020
main subject
neural stem cell
1 reference
based on heuristic
inferred from title
author
Barbara Stecca
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
2647769
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19214186%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 January 2020
author name string
Ariel Ruiz i Altaba
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
2647769
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19214186%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 January 2020
language of work or name
English
0 references
publication date
12 February 2009
1 reference
stated in
Europe PubMed Central
PMC publication ID
2647769
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19214186%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 January 2020
published in
The EMBO Journal
1 reference
stated in
Europe PubMed Central
PMC publication ID
2647769
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19214186%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 January 2020
volume
28
1 reference
stated in
Europe PubMed Central
PMC publication ID
2647769
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19214186%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 January 2020
issue
6
1 reference
stated in
Europe PubMed Central
PMC publication ID
2647769
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19214186%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 January 2020
page(s)
663-676
1 reference
stated in
Europe PubMed Central
PMC publication ID
2647769
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19214186%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 January 2020
cites work
Novel human glioma-associated oncogene 1 (GLI1) splice variants reveal distinct mechanisms in the terminal transduction of the hedgehog signal
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647769
retrieved
14 September 2017
Hedgehog signaling overrides p53-mediated tumor suppression by activating Mdm2
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647769
retrieved
14 September 2017
Sonic Hedgehog regulates Hes1 through a novel mechanism that is independent of canonical Notch pathway signalling.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647769
retrieved
14 September 2017
The Gli code: an information nexus regulating cell fate, stemness and cancer.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647769
retrieved
14 September 2017
Cancer and ageing: convergent and divergent mechanisms
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647769
retrieved
14 September 2017
Induction of sonic hedgehog mediators by transforming growth factor-beta: Smad3-dependent activation of Gli2 and Gli1 expression in vitro and in vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647769
retrieved
14 September 2017
Genetic pathways to primary and secondary glioblastoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647769
retrieved
14 September 2017
Melanomas require HEDGEHOG-GLI signaling regulated by interactions between GLI1 and the RAS-MEK/AKT pathways.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647769
retrieved
14 September 2017
HEDGEHOG-GLI1 signaling regulates human glioma growth, cancer stem cell self-renewal, and tumorigenicity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647769
retrieved
14 September 2017
Increasing p16INK4a expression decreases forebrain progenitors and neurogenesis during ageing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647769
retrieved
14 September 2017
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647769
retrieved
14 September 2017
Selective modulation of Hedgehog/GLI target gene expression by epidermal growth factor signaling in human keratinocytes.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647769
retrieved
14 September 2017
alphaE-catenin controls cerebral cortical size by regulating the hedgehog signaling pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647769
retrieved
14 September 2017
Phosphoinositide 3-kinase and Akt are essential for Sonic Hedgehog signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647769
retrieved
14 September 2017
Jagged1 signals in the postnatal subventricular zone are required for neural stem cell self-renewal.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647769
retrieved
14 September 2017
Cooperative requirement of the Gli proteins in neurogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647769
retrieved
14 September 2017
Isolation of neural stem cells from the postnatal cerebellum
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647769
retrieved
14 September 2017
The p53 pathway: positive and negative feedback loops
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647769
retrieved
14 September 2017
Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647769
retrieved
14 September 2017
Inhibition of prostate cancer proliferation by interference with SONIC HEDGEHOG-GLI1 signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647769
retrieved
14 September 2017
Understanding the function-structure and function-mutation relationships of p53 tumor suppressor protein by high-resolution missense mutation analysis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647769
retrieved
14 September 2017
Sonic hedgehog regulates adult neural progenitor proliferation in vitro and in vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647769
retrieved
14 September 2017
Characterization of the physical interaction of Gli proteins with SUFU proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647769
retrieved
14 September 2017
The Sonic Hedgehog-Gli pathway regulates dorsal brain growth and tumorigenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647769
retrieved
14 September 2017
Sequential actions of BMP receptors control neural precursor cell production and fate
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647769
retrieved
14 September 2017
Gli2 functions in FGF signaling during antero-posterior patterning
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647769
retrieved
14 September 2017
Mouse Gli1 mutants are viable but have defects in SHH signaling in combination with a Gli2 mutation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647769
retrieved
14 September 2017
Regulation of Gli2 and Gli3 activities by an amino-terminal repression domain: implication of Gli2 and Gli3 as primary mediators of Shh signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647769
retrieved
14 September 2017
Subventricular zone astrocytes are neural stem cells in the adult mammalian brain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647769
retrieved
14 September 2017
Gli proteins encode context-dependent positive and negative functions: implications for development and disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647769
retrieved
14 September 2017
Sonic hedgehog regulates the growth and patterning of the cerebellum
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647769
retrieved
14 September 2017
Activation of the transcription factor Gli1 and the Sonic hedgehog signalling pathway in skin tumours
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647769
retrieved
14 September 2017
Altered Neural Cell Fates and Medulloblastoma in Mouse patched Mutants
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647769
retrieved
14 September 2017
Gli1 is a target of Sonic hedgehog that induces ventral neural tube development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647769
retrieved
14 September 2017
Control of the reversibility of cellular quiescence by the transcriptional repressor HES1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647769
retrieved
29 September 2017
Genomic changes and gene expression profiles reveal that established glioma cell lines are poorly representative of primary human gliomas
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647769
retrieved
29 September 2017
A novel protein-processing domain in Gli2 and Gli3 differentially blocks complete protein degradation by the proteasome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647769
retrieved
29 September 2017
Transplanted glioma cells migrate and proliferate on host brain vasculature: a dynamic analysis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647769
retrieved
29 September 2017
Transcriptional activity of GLI1 is negatively regulated by protein kinase A.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647769
retrieved
29 September 2017
Mediation of Sonic Hedgehog-Induced Expression of COUP-TFII by a Protein Phosphatase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647769
retrieved
29 September 2017
Gli1 induces G2/M arrest and apoptosis in hippocampal but not tumor-derived neural stem cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647769
retrieved
27 June 2018
Dual degradation signals control Gli protein stability and tumor formation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647769
retrieved
27 June 2018
Regulation of Gli1 localization by the cAMP/protein kinase A signaling axis through a site near the nuclear localization signal
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647769
retrieved
27 June 2018
Sonic hedgehog controls stem cell behavior in the postnatal and adult brain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647769
retrieved
27 June 2018
P53 activity is essential for normal development in Xenopus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647769
retrieved
27 June 2018
PP2A:B56epsilon is required for eye induction and eye field separation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647769
retrieved
3 September 2018
Loss of p53 induces changes in the behavior of subventricular zone cells: implication for the genesis of glial tumors.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647769
retrieved
3 September 2018
p53 suppresses the self-renewal of adult neural stem cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647769
retrieved
3 September 2018
p21 loss compromises the relative quiescence of forebrain stem cell proliferation leading to exhaustion of their proliferation capacity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647769
retrieved
3 September 2018
Hedgehog-GLI signaling regulates the behavior of cells with stem cell properties in the developing neocortex.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647769
retrieved
3 September 2018
Loss of p53 but not ARF accelerates medulloblastoma in mice heterozygous for patched.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647769
retrieved
3 September 2018
GLI activates transcription through a herpes simplex viral protein 16-like activation domain.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647769
retrieved
3 September 2018
Antagonizing cAMP-dependent protein kinase A in the dorsal CNS activates a conserved Sonic hedgehog signaling pathway.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647769
retrieved
3 September 2018
Identifiers
DOI
10.1038/EMBOJ.2009.16
1 reference
stated in
Europe PubMed Central
PMC publication ID
2647769
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19214186%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 January 2020
PMC publication ID
2647769
1 reference
stated in
Europe PubMed Central
PMC publication ID
2647769
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19214186%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 January 2020
PubMed publication ID
19214186
1 reference
stated in
Europe PubMed Central
PMC publication ID
2647769
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19214186%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 January 2020
ResearchGate publication ID
24005213
0 references
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit