(Q38218964)

31 August 2017

title

Transcriptional outcome of telomere signalling (English)

1 reference

31 August 2017

Jing Ye

1 reference

31 August 2017

Valérie M Renault

series ordinal

1 reference

31 August 2017

Karine Jamet

series ordinal

1 reference

31 August 2017

Eric Gilson

series ordinal

1 reference

31 August 2017

publication date

10 June 2014

1 reference

31 August 2017

published in

Nature Reviews Genetics

1 reference

31 August 2017

1 reference

31 August 2017

1 reference

31 August 2017

page(s)

491-503

1 reference

Switching and signaling at the telomere

31 August 2017

cites work

1 reference

Shelterin: the protein complex that shapes and safeguards human telomeres

21 January 2018

1 reference

One identity or more for telomeres?

21 January 2018

1 reference

Involvement of the silencer and UAS binding protein RAP1 in regulation of telomere length

21 January 2018

1 reference

Distortion of the DNA double helix by RAP1 at silencers and multiple telomeric binding sites.

21 January 2018

1 reference

A novel Rap1p-interacting factor, Rif2p, cooperates with Rif1p to regulate telomere length in Saccharomyces cerevisiae.

21 January 2018

1 reference

SIR proteins and the assembly of silent chromatin in budding yeast

21 January 2018

1 reference

Telomeric repeat containing RNA and RNA surveillance factors at mammalian chromosome ends

21 January 2018

1 reference

Developmentally regulated transcription of mammalian telomeres by DNA-dependent RNA polymerase II.

21 January 2018

1 reference

Position effect at S. cerevisiae telomeres: reversible repression of Pol II transcription

21 January 2018

1 reference

How telomeres are replicated

21 January 2018

1 reference

Telomeres and telomerase: the path from maize, Tetrahymena and yeast to human cancer and aging

21 January 2018

1 reference

21 January 2018

The telomere syndromes

1 reference

A telomere-dependent DNA damage checkpoint induced by prolonged mitotic arrest

21 January 2018

1 reference

Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation

21 January 2018

1 reference

Environmental stresses disrupt telomere length homeostasis

21 January 2018

1 reference

Reduced telomerase activity in human T lymphocytes exposed to cortisol

21 January 2018

1 reference

Accelerated telomere shortening in response to life stress

21 January 2018

1 reference

Telomere length in early life predicts lifespan.

21 January 2018

1 reference

A DNA damage checkpoint response in telomere-initiated senescence

21 January 2018

1 reference

DNA damage foci at dysfunctional telomeres

21 January 2018

1 reference

The genome-wide expression response to telomerase deletion in Saccharomyces cerevisiae

21 January 2018

1 reference

Telomere length regulates ISG15 expression in human cells

21 January 2018

1 reference

Telomerase: central regulator of all of the hallmarks of cancer

21 January 2018

1 reference

Telomere length influences cancer cell differentiation in vivo.

21 January 2018

1 reference

TRF2 inhibits a cell-extrinsic pathway through which natural killer cells eliminate cancer cells

21 January 2018

1 reference

RAP1 protects from obesity through its extratelomeric role regulating gene expression

21 January 2018

1 reference

Nontelomeric role for Rap1 in regulating metabolism and protecting against obesity

21 January 2018

1 reference

Rap1 relocalization contributes to the chromatin-mediated gene expression profile and pace of cell senescence

21 January 2018

1 reference

The function of telomere clustering in yeast: the circe effect.

21 January 2018

1 reference

The clustering of telomeres and colocalization with Rap1, Sir3, and Sir4 proteins in wild-type Saccharomyces cerevisiae

21 January 2018

1 reference

The biology of replicative senescence

21 January 2018

1 reference

Relocalization of telomeric Ku and SIR proteins in response to DNA strand breaks in yeast

21 January 2018

1 reference

MEC1-dependent redistribution of the Sir3 silencing protein from telomeres to DNA double-strand breaks

21 January 2018

1 reference

DNA damage triggers disruption of telomeric silencing and Mec1p-dependent relocation of Sir3p

21 January 2018

1 reference

Localization of telomeres and telomere-associated proteins in telomerase-negative Saccharomyces cerevisiae

21 January 2018

1 reference

Redistribution of silencing proteins from telomeres to the nucleolus is associated with extension of life span in S. cerevisiae.

21 January 2018

1 reference

The functional importance of telomere clustering: global changes in gene expression result from SIR factor dispersion

21 January 2018

1 reference

Rif1 and Rif2 shape telomere function and architecture through multivalent Rap1 interactions

21 January 2018

1 reference

Reduced histone biosynthesis and chromatin changes arising from a damage signal at telomeres

21 January 2018

1 reference

Sir3p phosphorylation by the Slt2p pathway effects redistribution of silencing function and shortened lifespan.

21 January 2018

1 reference

Dynamics of Sir3 spreading in budding yeast: secondary recruitment sites and euchromatic localization

21 January 2018

1 reference

Regulating repression: roles for the sir4 N-terminus in linker DNA protection and stabilization of epigenetic states

21 January 2018

1 reference

Rif1 controls DNA replication timing in yeast through the PP1 phosphatase Glc7.

21 January 2018

1 reference

Highly expressed loci are vulnerable to misleading ChIP localization of multiple unrelated proteins

21 January 2018

1 reference

Telomeric localization of TRF2, a novel human telobox protein

21 January 2018

1 reference

Human telomeres contain two distinct Myb-related proteins, TRF1 and TRF2

21 January 2018

1 reference

Cytochrome c deficiency causes embryonic lethality and attenuates stress-induced apoptosis

21 January 2018

1 reference

Mammalian Rap1 controls telomere function and gene expression through binding to telomeric and extratelomeric sites

21 January 2018

1 reference

Human telomeric proteins occupy selective interstitial sites

21 January 2018

1 reference

Telomere-independent Rap1 is an IKK adaptor and regulates NF-kappaB-dependent gene expression

21 January 2018

1 reference

In vivo stoichiometry of shelterin components

21 January 2018

1 reference

PRL-3 activates NF-κB signaling pathway by interacting with RAP1

21 January 2018

1 reference

Control of human telomere length by TRF1 and TRF2

21 January 2018

1 reference

Protection of internal (TTAGGG)n repeats in Chinese hamster cells by telomeric protein TRF1.

21 January 2018

1 reference

TRF2 and apollo cooperate with topoisomerase 2alpha to protect human telomeres from replicative damage

21 January 2018

1 reference

The human TTAGGG repeat factors 1 and 2 bind to a subset of interstitial telomeric sequences and satellite repeats

21 January 2018

1 reference

Human intrachromosomal telomeric-like repeats: sequence organization and mechanisms of origin

21 January 2018

1 reference

Promoter-specific binding of Rap1 revealed by genome-wide maps of protein-DNA association

21 January 2018

1 reference

TRF2 promotes, remodels and protects telomeric Holliday junctions

21 January 2018

1 reference

The N-terminal domains of TRF1 and TRF2 regulate their ability to condense telomeric DNA.

21 January 2018

1 reference

Human Rap1 interacts directly with telomeric DNA and regulates TRF2 localization at the telomere

21 January 2018

1 reference

Telomere protection and TRF2 expression are enhanced by the canonical Wnt signalling pathway.

21 January 2018

1 reference

Dynamics of protein binding to telomeres in living cells: implications for telomere structure and function

21 January 2018

1 reference

Nontelomeric TRF2-REST interaction modulates neuronal gene silencing and fate of tumor and stem cells

21 January 2018

1 reference

Human Rif1 protein binds aberrant telomeres and aligns along anaphase midzone microtubules

21 January 2018

1 reference

53BP1 regulates DSB repair using Rif1 to control 5' end resection

21 January 2018

1 reference

Mouse Rif1 is a key regulator of the replication-timing programme in mammalian cells

21 January 2018

1 reference

Rif1 maintains telomere length homeostasis of ESCs by mediating heterochromatin silencing

21 January 2018

1 reference

Role of TRF2 in the assembly of telomeric chromatin.

21 January 2018

1 reference

TRF2 controls telomeric nucleosome organization in a cell cycle phase-dependent manner

21 January 2018

1 reference

TRF2 functions as a protein hub and regulates telomere maintenance by recognizing specific peptide motifs

21 January 2018

1 reference

The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.

21 January 2018

1 reference

TERRA RNA binding to TRF2 facilitates heterochromatin formation and ORC recruitment at telomeres

21 January 2018

1 reference

A chromatin-mediated mechanism for specification of conditional transcription factor targets

21 January 2018

1 reference

Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1alpha null mice

21 January 2018

1 reference

PGC-1alpha deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis

21 January 2018

1 reference

IKK-beta links inflammation to obesity-induced insulin resistance

21 January 2018

1 reference

Activation of innate immunity system during aging: NF-kB signaling is the molecular culprit of inflamm-aging

21 January 2018

1 reference

Loss of Rap1 induces telomere recombination in the absence of NHEJ or a DNA damage signal

21 January 2018

1 reference

TRF2 is in neuroglial cytoplasm and induces neurite-like processes

21 January 2018

1 reference

Telomere protection mechanisms change during neurogenesis and neuronal maturation: newly generated neurons are hypersensitive to telomere and DNA damage

21 January 2018

1 reference

The identification of zebrafish mutants showing alterations in senescence-associated biomarkers

21 January 2018

1 reference

TRF2 dysfunction elicits DNA damage responses associated with senescence in proliferating neural cells and differentiation of neurons.

21 January 2018

1 reference

Nontelomeric splice variant of telomere repeat-binding factor 2 maintains neuronal traits by sequestering repressor element 1-silencing transcription factor

21 January 2018

1 reference

FoxO3 regulates neural stem cell homeostasis

21 January 2018

1 reference

FOXO3 shares common targets with ASCL1 genome-wide and inhibits ASCL1-dependent neurogenesis.

21 January 2018

1 reference

Genomic maps of long noncoding RNA occupancy reveal principles of RNA-chromatin interactions

21 January 2018

1 reference

TERT promotes epithelial proliferation through transcriptional control of a Myc- and Wnt-related developmental program

21 January 2018

1 reference

Telomerase modulates Wnt signalling by association with target gene chromatin

21 January 2018

1 reference

Reversible cell-cycle entry in adult kidney podocytes through regulated control of telomerase and Wnt signaling

21 January 2018

1 reference

Maintenance of tumor initiating cells of defined genetic composition by nucleostemin

21 January 2018

1 reference

Alternatively spliced telomerase reverse transcriptase variants lacking telomerase activity stimulate cell proliferation

21 January 2018

1 reference

Comparing effects of mTR and mTERT deletion on gene expression and DNA damage response: a critical examination of telomere length maintenance-independent roles of telomerase

21 January 2018

1 reference

Phenotypes in mTERT⁺/⁻ and mTERT⁻/⁻ mice are due to short telomeres, not telomere-independent functions of telomerase reverse transcriptase

21 January 2018

1 reference

Telomeres, a busy platform for cell signaling.

21 January 2018

1 reference

An investigation of the effects of the core protein telomerase reverse transcriptase on Wnt signaling in breast cancer cells

21 January 2018

1 reference

Telomerase directly regulates NF-κB-dependent transcription.

21 January 2018

1 reference

Wnt/β-catenin signaling regulates telomerase in stem cells and cancer cells

21 January 2018

1 reference

NF-kappa B regulates transcription of the mouse telomerase catalytic subunit

21 January 2018

1 reference

Human telomerase reverse transcriptase regulates MMP expression independently of telomerase activity via NF-κB-dependent transcription

21 January 2018

1 reference

Post-translational modifications of TRF1 and TRF2 and their roles in telomere maintenance.

21 January 2018

1 reference

Tankyrase, a poly(ADP-ribose) polymerase at human telomeres

21 January 2018

1 reference

Functional subdomain in the ankyrin domain of tankyrase 1 required for poly(ADP-ribosyl)ation of TRF1 and telomere elongation

21 January 2018

1 reference

TRF1 is degraded by ubiquitin-mediated proteolysis after release from telomeres

21 January 2018

1 reference

Functional interaction between poly(ADP-Ribose) polymerase 2 (PARP-2) and TRF2: PARP activity negatively regulates TRF2.

21 January 2018

1 reference

PARP1 Is a TRF2-associated poly(ADP-ribose)polymerase and protects eroded telomeres

21 January 2018

1 reference

Positive feedback between p53 and TRF2 during telomere-damage signalling and cellular senescence.

21 January 2018

1 reference

p300-mediated acetylation of TRF2 is required for maintaining functional telomeres

21 January 2018

1 reference

Mammalian telomeres end in a large duplex loop

21 January 2018

1 reference

SIR2 and SIR4 interactions differ in core and extended telomeric heterochromatin in yeast

21 January 2018

1 reference

A methyltransferase targeting assay reveals silencer-telomere interactions in budding yeast

21 January 2018

1 reference

Chromosome looping in yeast: telomere pairing and coordinated movement reflect anchoring efficiency and territorial organization

21 January 2018

1 reference

Homologous recombination generates T-loop-sized deletions at human telomeres

21 January 2018

1 reference

ERCC1/XPF protects short telomeres from homologous recombination in Arabidopsis thaliana

21 January 2018

1 reference

Cohabitation of insulators and silencing elements in yeast subtelomeric regions

21 January 2018

1 reference

A telomere-binding protein (TRF2/MTBP) from mouse nuclear matrix with motives of an intermediate filament-type rod domain

21 January 2018

1 reference

Identification of a perinuclear positioning element in human subtelomeres that requires A-type lamins and CTCF.

21 January 2018

1 reference

Human telomeres are tethered to the nuclear envelope during postmitotic nuclear assembly.

21 January 2018

1 reference

RAP1 and telomere structure regulate telomere position effects in Saccharomyces cerevisiae.

21 January 2018

1 reference

Telomere folding is required for the stable maintenance of telomere position effects in yeast

21 January 2018

1 reference

A haploid-specific transcriptional response to irradiation in Saccharomyces cerevisiae

21 January 2018

1 reference

Clustering heterochromatin: Sir3 promotes telomere clustering independently of silencing in yeast

21 January 2018

1 reference

Mutation of yeast Ku genes disrupts the subnuclear organization of telomeres

21 January 2018

1 reference

Ku-deficient yeast strains exhibit alternative states of silencing competence

21 January 2018

1 reference

Telomere position effect in human cells

21 January 2018

1 reference

Telomere length regulates the epigenetic status of mammalian telomeres and subtelomeres

21 January 2018

1 reference

Telomere length regulates TERRA levels through increased trimethylation of telomeric H3K9 and HP1α.

21 January 2018

1 reference

Telomere position effect regulates DUX4 in human facioscapulohumeral muscular dystrophy

21 January 2018

1 reference

Telomere shortening relaxes X chromosome inactivation and forces global transcriptome alterations

21 January 2018

1 reference

SIRT6 is required for maintenance of telomere position effect in human cells

21 January 2018

1 reference

Human telomeric position effect is determined by chromosomal context and telomeric chromatin integrity

21 January 2018

1 reference

The heterochromatin protein 1 prevents telomere fusions in Drosophila

21 January 2018

1 reference

Methylated TRF2 associates with the nuclear matrix and serves as a potential biomarker for cellular senescence.

21 January 2018

1 reference

Human telomeric protein TRF2 associates with genomic double-strand breaks as an early response to DNA damage.

21 January 2018

1 reference

Short telomeres compromise β-cell signaling and survival

21 January 2018

1 reference

DNA processing is not required for ATM-mediated telomere damage response after TRF2 deletion

21 January 2018

1 reference

Linking functional decline of telomeres, mitochondria and stem cells during ageing

21 January 2018

1 reference

Telomere length and type 2 diabetes in males, a premature aging syndrome

21 January 2018

1 reference

Telomeric and extra-telomeric roles for telomerase and the telomere-binding proteins

21 January 2018

1 reference

Telomere-binding protein Taz1 controls global replication timing through its localization near late replication origins in fission yeast

21 January 2018

1 reference

Protein phosphatase 1 recruitment by Rif1 regulates DNA replication origin firing by counteracting DDK activity

21 January 2018

1 reference

Rif1 controls DNA replication by directing Protein Phosphatase 1 to reverse Cdc7-mediated phosphorylation of the MCM complex

21 January 2018

1 reference

Mitochondrial localization of telomeric protein TIN2 links telomere regulation to metabolic control

21 January 2018

1 reference

The major reverse transcriptase-incompetent splice variant of the human telomerase protein inhibits telomerase activity but protects from apoptosis

21 January 2018

1 reference

Telomeric RNAs mark sex chromosomes in stem cells.

21 January 2018

1 reference

Telomere looping permits gene activation by a downstream UAS in yeast

21 January 2018

1 reference

RAP1 protein interacts with yeast telomeres in vivo: overproduction alters telomere structure and decreases chromosome stability

21 January 2018

1 reference

Mild Hyperoxia Shortens Telomeres and Inhibits Proliferation of Fibroblasts: A Model for Senescence?

31 March 2020

1 reference

Evidence for silencing compartments within the yeast nucleus: a role for telomere proximity and Sir protein concentration in silencer-mediated repression

31 March 2020

1 reference

Silencing of genes at nontelomeric sites in yeast is controlled by sequestration of silencing factors at telomeres by Rap 1 protein

31 March 2020

1 reference

Identification of human Rap1: implications for telomere evolution

31 March 2020

1 reference

Genome-wide YFP fluorescence complementation screen identifies new regulators for telomere signaling in human cells

31 March 2020

1 reference

TRF2-mediated stabilization of hREST4 is critical for the differentiation and maintenance of neural progenitors.

31 March 2020

1 reference

Human telomeres are attached to the nuclear matrix

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24913665

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NRG3743

1 reference

Dimensions Publication ID

31 August 2017

1015315311

0 references

1 reference